29 unknown. 29 Phase 2, 9 Phase 3, 8 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 29 | Unknown 29 |
| Phase 3 | 9 | Unknown 9 |
| Phase 1 | 8 | Unknown 8 |
Follow Dyssomnias: new trials by email Literature Review of Dyssomnias trials Research Report on Dyssomnias
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Randomized, Placebo-controlled Trial of Prednisone in Refractory Restless Legs Syndrome: a Pilot Study Prednisone, Placebo - Restless Legs Syndrome | Phase 1 / Phase 2 | Unknown | Scripps Health | 50 | 2024-10-01 | 2024-10-08 |
| Phase Ⅰb/Ⅱ Study of HS-10506 in Chinese Participants With Insomnia Disorder HS-10506, Placebo - Insomnia Disorder | Phase 1 / Phase 2 | Unknown | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 312 | 2024-05-01 | 2024-04-23 |
| Benefits of a Cannabidiolic Acid Topical Cream for the Treatment of Restless Leg Syndrome Chylobinoid Topical Cream - Restless Legs Syndrome | Phase 1 / Phase 2 | Unknown | Synthonics Inc | 10 | 2024-03-01 | 2024-08-28 |
| Impact of Early Ventilation in Stroke Outcomes in Patients With Sleep Apnea After First Ever Stroke Adaptive Servoventilation (ASV) therapy, Best medical treatment - Stroke, Sleep Apnea | Phase 2 | Unknown | Philips Portuguesa S.A. | 90 | 2024-02-27 | 2024-08-12 |
| SMILES: Study of Montelukast in Sickle Cell Disease Montelukast, Oral Placebo - Anemia, Sickle Cell, Sleep-Disordered Breathing | Phase 2 / Phase 3 | Unknown | Great Ormond Street Hospital for Children NHS Foundation Trust | 200 | 2023-10-16 | 2023-11-01 |
| A Pilot Study of Antioxidant Therapy in Obstructive Sleep Apnea Patients Alpha Lipoic Acid 600 MG Oral Tablet, Placebo - Obstructive Sleep Apnea of Adult | Phase 2 / Phase 3 | Unknown | University of British Columbia | 80 | 2022-06-01 | 2022-05-25 |
| Identifying Sleep Apnea Patients That Best Respond to Atomoxetine Plus Oxybutynin Therapy Atomoxetine, Oxybutynin - Obstructive Sleep Apnea | Phase 1 / Phase 2 | Unknown | Brigham and Women's Hospital | 22 | 2022-05-05 | 2023-10-18 |
| Biolab Zolpidem Orodispersible 1.0 mg, 1.75 mg and 3.5 mg to Treat Maintenance Insomnia Disorder. Zolpidem - Insomnia Disorder | Phase 2 / Phase 3 | Unknown | Biolab Sanus Farmaceutica | 366 | 2021-03-01 | 2020-07-27 |
| Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2 PurWet, FurFat, PurApo - Sequelae of; Infection, Post Infection Glomerulonephritis | Phase 1 / Phase 2 | Unknown | All Natural Medicine Clinic, LLC | 2000 | 2021-03-01 | 2021-05-26 |
| Treatment of Restless Legs Syndrome With the Hypocretin Antagonist Suvorexant Suvorexant, Placebo - Restless Legs Syndrome | Phase 2 | Unknown | Diego García-Borreguero, MD, PhD | 43 | 2019-02-01 | 2018-11-29 |
| Outcomes Mandate National Integration With Cannabis as Medicine Cannabis, Medical, RYAH-Medtech Inhaler - Chronic Pain, Chronic Pain Syndrome | Phase 2 | Unknown | OMNI Medical Services, LLC | 200000 | 2018-12-01 | 2022-06-02 |
| Knee Arthritis Treatment With Autologous Fragmented Adipose Tissue and PRP - Comparison of Two Treatment Methods autologous adipose tissue transfer, PRP injections - Osteo Arthritis Knee, Knee Osteoarthritis | Phase 2 | Unknown | Rehasport Clinic | 60 | 2018-07-30 | 2020-03-25 |
| A Study to Examine the Efficacy of a Therapeutic THX-110 for Obstructive Sleep Apnea THX-110 - Obstructive Sleep Apnea | Phase 2 | Unknown | Neurothera Labs Inc. | 30 | 2018-06-04 | 2018-08-24 |
| A Study of Oral BTD-001 in Adults With Idiopathic Hypersomnia Pentetrazol (PTZ), Placebo oral capsule - Idiopathic Hypersomnia | Phase 2 | Unknown | Balance Therapeutics | 80 | 2018-05-29 | 2020-04-29 |
| Mandibular Advancement Device for Treatment of Obstructive Sleep Apnea and Its Impact on Cardiac Remodeling Mandibular advancement device - Obstructive Sleep Apnea, Heart Failure | Phase 2 / Phase 3 | Unknown | National University of Singapore | 100 | 2018-05-01 | 2020-09-10 |
| Melatonin 3mg and 5mg Compared to Cognitive Behavioral Therapy for Insomnia (CBT-I) in the Treatment of Insomnia CBT-I plus placebo, CBT-I plus Melatonin 3 mg, CBT-I plus Melatonin 5 mg - Insomnia Disorder | Phase 2 / Phase 3 | Unknown | Ache Laboratorios Farmaceuticos S.A. | 307 | 2018-03-22 | 2020-09-03 |
| Vitamin D in the Treatment of Primary Restless Legs Syndrome Vitamin D - Restless Legs Syndrome | Phase 2 / Phase 3 | Unknown | King Abdulaziz University | 106 | 2015-12-01 | 2015-04-06 |
| Night Balance for Positional Obstructive Sleep Apnea Syndrome (POSAS) Positional vibrator belt - Obstructive Sleep Apnea (OSAS) | Phase 2 / Phase 3 | Unknown | Glostrup University Hospital, Copenhagen | 100 | 2014-05-01 | 2014-04-15 |
| Ketogenic Diet Treatment of Obesity With Co-morbid Type 2 Diabetes Mellitus and/or Obstructive Sleep Apnea Ketogenic diet, Orlistat, Standardized diet - Obesity, Diabetes | Phase 2 | Unknown | Mid-Atlantic Epilepsy and Sleep Center, LLC | 150 | 2014-01-01 | 2018-08-17 |
| Effects of Metoprolol and Amlodipine on Cardiac Remodeling, Arrhythmias and Blood Pressure Variation in Hypertensive Patients With Sleep Apnea Syndrome Amlodipine, metoprolol - Sleep Apnea Syndrome, Hypertension | Phase 2 / Phase 3 | Unknown | First Affiliated Hospital of Harbin Medical University | 20 | 2013-10-01 | 2017-02-15 |
Showing 20 of 29. Sign in to see all of them.
Sleep Apnea, Obstructive (10) · Sleep Initiation and Maintenance Disorders (7) · Sleep Apnea Syndromes (6) · Restless Legs Syndrome (5) · Anemia, Sickle Cell (2) · Anxiety Disorders (2) · Bipolar Disorder (2) · Depression (2) · Heart Failure (2) · Hypertension (2) · Respiratory Aspiration (2) · Stress Disorders, Post-Traumatic (2) · Acquired Immunodeficiency Syndrome (1) · Ageusia (1) · Amyotrophic Lateral Sclerosis (1)
Nervous System Diseases (29) · Sleep Disorders, Intrinsic (29) · Sleep Wake Disorders (28) · Respiratory Tract Diseases (17) · Respiration Disorders (16) · Apnea (15) · Mental Disorders (12) · Sleep Apnea Syndromes (10) · Pathological Conditions, Signs and Symptoms (8) · Cardiovascular Diseases (6) · Parasomnias (5) · Pathologic Processes (5) · Signs and Symptoms (5) · Behavior (4)
Amlodipine (1) · Atomoxetine Hydrochloride (1) · Carbon Dioxide (1) · Diet, Carbohydrate-Restricted (1) · Diet, Ketogenic (1) · Diet, Protein-Restricted (1) · Exercise (1) · Medical Marijuana (1) · Melatonin (1) · Metoprolol (1) · Occlusal Splints (1) · Orlistat (1) · Pentylenetetrazole (1) · Prednisone (1) · Tablets (1)
Imperial College London (2) · Ache Laboratorios Farmaceuticos S.A. (1) · All India Institute of Medical Sciences (1) · All Natural Medicine Clinic, LLC (1) · Balance Therapeutics (1) · Biolab Sanus Farmaceutica (1) · Brigham and Women's Hospital (1) · Diego García-Borreguero, MD, PhD (1) · First Affiliated Hospital of Harbin Medical University (1) · Glostrup University Hospital, Copenhagen (1) · Great Ormond Street Hospital for Children NHS Foundation Trust (1) · Jiangsu Hansoh Pharmaceutical Co., Ltd. (1) · King Abdulaziz University (1) · Liaoyang Central Hospital (1) · Mid-Atlantic Epilepsy and Sleep Center, LLC (1)
United States (8) · United Kingdom (3) · Canada (2) · China (2) · Austria (1) · Brazil (1) · Czechia (1) · Denmark (1) · France (1) · Germany (1) · Hungary (1) · India (1) · Israel (1) · Italy (1) · Poland (1)
Darrel P Francis, MD (2) · Andrei V. Alexandrov, MD (1) · Claire C. Bourguet, Ph.D. (1) · Colin M. Shapiro, MBBCh, PhD (1) · Dr. Ryan O Lakin, MD JD (1) · Fenella Kirkham, MA MB Bchir (1) · Jessica Kepplinger, MD (1) · Kristen H Archbold, PhD, RN (1) · Mark Esguerra, MD (1) · Mauro Crippa Jr. (1) · Morgan Lam (1) · Pavel Klein, M.D. (1) · Pawel Bakowski, MD PhD (1) · Philip Toennesen, M.D., Ph.D. (1) · Rachel Jen, MD (1)
PMID 23941576, PMID 30430372, PMID 32434498, PMID 33927689, PMID 34629091