18 completed. 18 Phase 2, 5 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 18 | Completed 18 |
| Phase 3 | 5 | Completed 5 |
| Phase 1 | 2 | Completed 2 |
Follow Dysphagia: new trials by email Literature Review of Dysphagia trials Research Report on Dysphagia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment of Dysphagia and Ineffective Esophageal Motility With Prucalopride: A Pilot Study Prucalopride - Ineffective Esophageal Motility, Dysphagia | Phase 2 | Completed | University of Calgary | 28 | 2017-10-20 | 2020-03-25 |
| Novel Management of Airway Protection in Parkinson's Disease: A Clinical Trial EMST, smTAP - Parkinson's Disease, Dysphagia | Phase 2 | Completed | Teachers College, Columbia University | 65 | 2016-09-01 | 2023-12-22 |
| Effect of Afferent Oropharyngeal Pharmacological and Electrical Stimulation on Swallow Response and on Activation of Human Cortex in Stroke Patients With Oropharyngeal Dysphagia Dietary and oral hygiene recommendations, oral TRPV1 agonist, pharyngeal electrical stimulation - Dysphagia, Aspiration | Phase 2 | Completed | Hospital de Mataró | 100 | 2012-10-01 | 2017-02-09 |
| Manuka Honey in Preventing Esophagitis-Related Pain in Patients Receiving Chemotherapy and Radiation Therapy For Lung Cancer Manuka honey in liquid form, Manuka honey in lozenge form, Standard supportive care - Dysphagia, Lung Cancer | Phase 2 | Completed | Radiation Therapy Oncology Group | 163 | 2012-02-01 | 2017-08-31 |
| Tongue Pressure Profile Training for Dysphagia Post Stroke Tongue Pressure Profile Training, Tongue-Pressure Strength-and-Accuracy Training - Dysphagia | Phase 2 | Completed | Toronto Rehabilitation Institute | 14 | 2011-09-01 | 2016-02-08 |
| Neuromuscular Electrical Stimulation (NMES) Treatment Technique Therapy in the Management of Young Infants With Severe Dysphagia Neuromuscular electrical stimulation (NMES) - Dysphagia | Phase 2 | Completed | The Hospital for Sick Children | 10 | 2010-09-01 | 2015-07-20 |
| Identifying and Treating Arousal Related Deficits in Neglect and Dysphagia Modafinil, Placebo, Baseline - Spatial Neglect, Dysphagia | Phase 2 | Completed | University of Arkansas | 28 | 2010-03-01 | 2016-10-18 |
| Functional Electrical Stimulation in Irradiated Nasopharyngeal Carcinoma (NPC) Functional electrical stimulation, Exercise home program - Dysphagia | Phase 2 | Completed | National Taiwan University Hospital | 20 | 2008-07-01 | 2014-03-26 |
| Adjunctive Neuromuscular Electrical Stimulation for the Rehabilitation of Swallowing swallowing therapy - Dysphagia | Phase 2 / Phase 3 | Completed | University of Florida | 53 | 2008-04-01 | 2012-01-05 |
| Transcranial Direct Current Stimulation (TDCS) for Facilitating Swallowing Improvement After an Acute Unilateral Hemispheric Stroke tDCS, Sham - Dysphagia | Phase 1 / Phase 2 | Completed | Beth Israel Deaconess Medical Center | 19 | 2007-04-01 | 2014-02-28 |
| Pharyngocise Dose Response Study Pharyngocise - Dysphagia | Phase 2 / Phase 3 | Completed | University of Florida | 130 | 2006-06-01 | 2012-01-05 |
| Volitional Swallowing in Stroke Patients With Chronic Dysphagia Swallowing Training - Stroke, Dysphagia | Phase 2 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 34 | 2006-03-17 | 2017-07-02 |
| Nutritional Therapy for Stroke Patients Nutritional support - Stroke, Malnutrition | Phase 2 / Phase 3 | Completed | Ostfold Hospital Trust | 125 | 2005-05-01 | 2009-05-11 |
| Study to Evaluate Palifermin in the Reduction of Dysphagia in Patients With Locally Advanced Non-Small Cell Lung Cancer (NSCLC) Palifermin, Placebo, Radiotherapy - Dysphagia, Non-Small Cell Lung Cancer | Phase 2 | Completed | Swedish Orphan Biovitrum | 100 | 2005-01-01 | 2017-03-14 |
| Treatment of Dysphagia Using the Mendelsohn Maneuver Mendelsohn Maneuver - Stroke, Dysphagia | Phase 1 / Phase 2 | Completed | University of Arkansas | 18 | 2003-07-01 | 2018-03-20 |
| Effects of Age and Age-Related Diseases on Swallowing Lingual Strengthening - Dysphagia | Phase 2 | Completed | US Department of Veterans Affairs | 60 | 2002-01-01 | 2008-05-06 |
| Trial of Electrosurgical Incision Versus Bougie Dilation of Symptomatic Lower Esophageal (Schatzki's) Rings Bougie Dilation, Needle-knife incision - Lower Esophageal Ring, Dysphagia | Phase 2 / Phase 3 | Completed | University of Utah | 50 | 2001-08-01 | 2008-01-04 |
| Behavioural Intervention for Dysphagia in Acute Stroke behavioral swallowing exercises/ strategies - Dysphagia | Phase 2 / Phase 3 | Completed | Royal Perth Hospital | 300 | 1996-05-01 | 2006-05-05 |
Deglutition Disorders (18) · Stroke (8) · Carcinoma, Non-Small-Cell Lung (2) · Lung Neoplasms (2) · Cough (1) · Esophageal Ring, Lower (1) · Esophagitis (1) · Gastroesophageal Reflux (1) · Head and Neck Neoplasms (1) · Malnutrition (1) · Nasopharyngeal Carcinoma (1) · Pain (1) · Parkinson Disease (1) · Small Cell Lung Carcinoma (1) · Weight Loss (1)
Digestive System Diseases (18) · Esophageal Diseases (18) · Gastrointestinal Diseases (18) · Otorhinolaryngologic Diseases (18) · Pharyngeal Diseases (18) · Brain Diseases (9) · Central Nervous System Diseases (9) · Nervous System Diseases (9) · Cardiovascular Diseases (8) · Cerebrovascular Disorders (8) · Vascular Diseases (8) · Neoplasms (4) · Neoplasms by Site (4) · Pathological Conditions, Signs and Symptoms (3) · Respiratory Tract Diseases (3)
BaseLine dental cement (1) · Carboplatin (1) · Diet (1) · Electrodes (1) · Fibroblast Growth Factor 7 (1) · Modafinil (1) · Noble Gases (1) · Nutritional Support (1) · Paclitaxel (1) · Radiotherapy (1) · Range of Motion, Articular (1) · Transcranial Direct Current Stimulation (1) · Transcutaneous Electric Nerve Stimulation (1) · prucalopride (1) · salicylhydroxamic acid (1)
University of Arkansas (2) · University of Florida (2) · Beth Israel Deaconess Medical Center (1) · Hospital de Mataró (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · National Taiwan University Hospital (1) · Ostfold Hospital Trust (1) · Radiation Therapy Oncology Group (1) · Royal Perth Hospital (1) · Swedish Orphan Biovitrum (1) · Teachers College, Columbia University (1) · The Hospital for Sick Children (1) · Toronto Rehabilitation Institute (1) · US Department of Veterans Affairs (1) · University of Calgary (1)
United States (10) · Canada (3) · Australia (1) · Norway (1) · Spain (1)
Giselle Carnaby-Mann, PhD (2) · Catriona M Steele, Ph.D. (1) · Gary H McCullough, Ph.D. (1) · Gary McCullough, PhD (1) · Giselle D Mann, MPH,PhD (1) · Graeme Hankey, MBBS, MD, (1) · James A DiSario, M.D. (1) · Joanne Robbins, PhD (1) · John Fang, M.D. (1) · Lawrence B. Berk, MD, PhD (1) · Mark S Mennemeier, PhD (1) · Michelle Buresi, MD, PhD (1) · Pere Pere, Doctor (1) · Sandeep Kumar, MD (1)
PMID 16137276, PMID 16361020, PMID 17270511, PMID 17602265, PMID 20176418, PMID 20955603, PMID 21441148, PMID 23782628, PMID 30740545, PMID 36345090
R03DC004942 (1), R21HD054752 (1), R21HD055677 (1)