162 completed, 54 unknown, 39 recruiting, 11 active not recruiting. 218 Not applicable, 11 Phase 2, 10 Phase 1, 5 Phase 4, 4 Early Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Whole Selves User Testing and Feasibility Study Whole Selves - Alcohol Use, Unspecified, Relationship, Social | Not applicable | Not yet recruiting | Boston University | 107 | 2027-09-01 | 2026-07-28 |
| Managing Hepatitis B (Hep. B) and Human Papilloma Virus (HPV) Related Cancers and Mental Health. Gardasil 9 vaccine, Hepatitis B Virus Vaccine(HBV), Cognitive Behavioral Therapy - Hepatitis B, Human Papilloma Virus | Phase 4 | Not yet recruiting | Eunice Dube | 2140 | 2027-01-30 | 2026-07-30 |
| Youth Emotional and Behavioral Treatment Study Cognitive Behavioral Therapy - Depression, Anxiety | Not applicable | Recruiting | Florida State University | 500 | 2026-05-07 | 2026-05-14 |
| Promoting Mental Health of Teachers and Caregiver Using a Personalized mHealth Toolkit in Uganda mHealth Toolkit for Wellness & Empowering Lives of School Community (mWEL) - Mental Health Literacy, Depression, Anxiety | Not applicable | Recruiting | NYU Langone Health | 1180 | 2026-04-22 | 2026-07-22 |
| ACT-based Parenting Program for Caregivers of Children With Hearing Loss Post-cochlear: A Pilot Randomised Controlled Trial ACT-based parenting program+usual care, Usual care - Hearing Loss, Stress | Not applicable | Not yet recruiting | Second Xiangya Hospital of Central South University | 64 | 2026-03-28 | 2026-03-17 |
| The COMParing App Support Strategies Study Introductory Coaching Session, Introductory Information Session, On-Demand Email or Text Support - Depression, Anxiety | Not applicable | Recruiting | University of Wisconsin, Madison | 688 | 2026-03-13 | 2026-10-29 |
| Weekly Dynamics of Psychopathological and Symptom Networks During Mindfulness-Based Interventions for Emotional Distress Mindfulness Intervention for Emotional Distress (self-guided version) - Depression, Anxiety, Emotional Disorders | Not applicable | Recruiting | Peking University | 500 | 2025-11-16 | 2026-04-27 |
| Integrating Inuit Knowledge Principles in Multi-Level Mental Health Clinical Trials Traditional Country Foods, Cultural Workshops - Depression, Anxiety | Early Phase 1 | Completed | University of Alberta | 29 | 2025-10-15 | 2026-10-23 |
| Clinical Outcomes of a Digital Mental Health Intervention for Moderate/Severe Depression and Anxiety BetterHelp - Depression, Anxiety, Mental Health Issue | Not applicable | Completed | Teladoc Health | 86 | 2025-10-06 | 2026-08-26 |
| Multidimensional Sleep Health Intervention to Optimize Concussion Recovery Sleep Intervention - Concussion (Diagnosis), Concussion, Mild Traumatic Brain Injury | Not applicable | Recruiting | University of Colorado, Denver | 54 | 2025-09-10 | 2026-06-18 |
| SUpport From PEeRs to Expand Access Study - Community Behavioral: Supported dCBT, Behavioral: Unsupported dCBT - Depression, Anxiety | Not applicable | Recruiting | University of California, Berkeley | 213 | 2025-08-18 | 2025-09-22 |
| Building Connections Treatment as Usual, Building Connections Intervention - Cancer Colorectal, Cancer Cervix | Not applicable | Recruiting | Massachusetts General Hospital | 3600 | 2025-08-07 | 2025-11-18 |
| Personalized Education and Pain Response in Chronic Pancreatitis Personalised education - Chronic Pancreatitis, Pain Syndrome | Not applicable | Not yet recruiting | Asian Institute of Gastroenterology, India | 114 | 2025-08-01 | 2025-07-30 |
| Developing Evidence-Based Cognitive Approaches to Improve Adjustment to Vision Loss Integrated Cognitive Behavioral Therapy (CBT) & Mindfulness Group Intervention for Adjustment to Vision Loss - Depression, Anxiety, Visual Impairment | Not applicable | Recruiting | The Chicago Lighthouse | 45 | 2025-07-14 | 2025-07-30 |
| Test of Target Engagement of Ambiguity Aversion Uncertainty-focused single session intervention, Maintaining a healthy lifestyle single session intervention - Intolerance of Uncertainty, Anxiety | Not applicable | Recruiting | Northwestern University | 140 | 2025-07-07 | 2026-05-26 |
| Acceptance and Commitment Therapy-based Intervention for Parents of a Child With Medical Complexity ACT-based intervention - Acceptance and Commitment Therapy, Child With Medical Complexity | Not applicable | Completed | The Hong Kong Polytechnic University | 24 | 2025-07-02 | 2026-09-16 |
| Effects of Exercıse on Chronotype, Sleep Qualıty and Depressıon Symptom Level in Unıversıty Students Exercise - Depression, Anxiety, Chronotype | Not applicable | Active not recruiting | Aydin Adnan Menderes University | 54 | 2025-06-18 | 2025-10-02 |
| Psychological Adjustment to Long-term (PAL) Physical Conditions: A Randomised Cross-over Feasibility Trial of a Self-guided App Orbi - Depression, Anxiety, Chronic Disease | Not applicable | Completed | King's College London | 58 | 2025-06-10 | 2026-08-07 |
| Just-In-Time Adaptive Interventions (JITAIs) in a Digital Mental Health Intervention for Middle-Aged and Older Adults With Chronic Pain Just-In-Time Adaptive Interventions (JITAIs), Wysa for Chronic Pain - Chronic Pain, Depression, Anxiety | Not applicable | Recruiting | Washington University School of Medicine | 1000 | 2025-06-02 | 2026-05-05 |
| Sedentary Behavior and Depressive Symptoms Physical activity intervention, Standard of care - Depression, Anxiety | Not applicable | Recruiting | University of Sao Paulo General Hospital | 84 | 2025-06-01 | 2025-07-25 |
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Anxiety Disorders (289) · Depression (289) · Psychological Well-Being (22) · Stress Disorders, Post-Traumatic (17) · Sleep Initiation and Maintenance Disorders (13) · Motor Activity (11) · COVID-19 (9) · Stress, Psychological (9) · Chronic Pain (8) · Neoplasms (8) · Cognitive Dysfunction (7) · Breast Neoplasms (6) · Depressive Disorder (6) · Fatigue (6) · Pain (6)
Behavioral Symptoms (288) · Behavior (287) · Mental Disorders (284) · Pathological Conditions, Signs and Symptoms (53) · Signs and Symptoms (35) · Nervous System Diseases (32) · Pathologic Processes (25) · Neurologic Manifestations (24) · Personal Satisfaction (22) · Stress Disorders, Traumatic (20) · Trauma and Stressor Related Disorders (20) · Urogenital Diseases (19) · Infections (16) · Neoplasms (16) · Neurocognitive Disorders (15)
Cognitive Behavioral Therapy (10) · Mindfulness (6) · Therapeutics (6) · Mental Health (5) · Surveys and Questionnaires (5) · Exercise (4) · Standard of Care (3) · Transcranial Magnetic Stimulation (3) · Acceptance and Commitment Therapy (2) · Crisis Intervention (2) · Esketamine (2) · Eye Movement Desensitization Reprocessing (2) · Ketamine (2) · Mindfulness-Based Cognitive Therapy (2) · Psilocybin (2)
Stanford University (5) · Chinese University of Hong Kong (4) · University of Colorado, Denver (4) · Massachusetts General Hospital (3) · Mclean Hospital (3) · Montana State University (3) · Northwestern University (3) · The Hong Kong Polytechnic University (3) · University of Calgary (3) · University of California, Irvine (3) · University of Manitoba (3) · University of Regina (3) · University of Texas Southwestern Medical Center (3) · University of Wisconsin, Madison (3) · Washington University School of Medicine (3)
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Leslie E Roos, PhD (3) · David R Howell, PhD (2) · Fiona Yan-Yee Ho (2) · Heather Hadjistavropoulos, PhD (2) · Lianne Tomfohr-Madsen, PhD (2) · Stephen M Schueller, PhD (2) · Vikram Patel, PhD (2) · Xinghua Liu (2) · Abby L. Cheng, MD, MPHS (1) · Adrian Aguilera, PhD (1) · Adrian Lopresti, PhD (1) · Alejandro Martinez Rodriguez, Assistant (1) · Alethea Desrosiers (1) · Alex Clarke, MD (1)
PMID 10928201, PMID 14672796, PMID 14715399, PMID 16095934, PMID 16427171, PMID 17364516, PMID 18243894, PMID 19812460, PMID 20686627, PMID 21266141, PMID 22353021, PMID 22591515, PMID 22671966, PMID 22909316, PMID 23524595, PMID 23647804, PMID 25208108, PMID 25897757, PMID 27332879, PMID 28220089, PMID 28409729, PMID 29504794, PMID 29704969, PMID 3058677, PMID 30678679, PMID 31789601, PMID 3200278, PMID 32551797, PMID 32838678, PMID 33009852, PMID 33343425, PMID 33355633, PMID 33413109, PMID 33735647, PMID 33933665, PMID 33949959, PMID 33988517, PMID 34040886, PMID 34051772, PMID 34194374, PMID 34231203, PMID 34586075, PMID 35025538, PMID 35027938, PMID 35060914, PMID 35380673, PMID 35576997, PMID 35712448, PMID 35782290, PMID 35870990
2019 (2), P30CA012197 (2), K23HD113845 (1), K23MH120324 (1), K43TW011586 (1), P20GM104417 (1), P30DA029926 (1), R00AA030601 (1), R01CA258311 (1), R01HD108133 (1), R01MH116829 (1), R01MH124718 (1), R01MH126664 (1), R01MH131025 (1), R01MH131698 (1)