134 completed, 36 unknown, 24 recruiting, 7 active not recruiting. 218 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 218 | Completed 134, Unknown 36, Recruiting 24, Active not recruiting 7, Not yet recruiting 7, Enrolling by invitation 4, Terminated 4, Withdrawn 2 |
Follow Depression, Anxiety: new trials by email Literature Review of Depression, Anxiety trials Research Report on Depression, Anxiety
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Whole Selves User Testing and Feasibility Study Whole Selves - Alcohol Use, Unspecified, Relationship, Social | Not applicable | Not yet recruiting | Boston University | 107 | 2027-09-01 | 2026-07-28 |
| Youth Emotional and Behavioral Treatment Study Cognitive Behavioral Therapy - Depression, Anxiety | Not applicable | Recruiting | Florida State University | 500 | 2026-05-07 | 2026-05-14 |
| Promoting Mental Health of Teachers and Caregiver Using a Personalized mHealth Toolkit in Uganda mHealth Toolkit for Wellness & Empowering Lives of School Community (mWEL) - Mental Health Literacy, Depression, Anxiety | Not applicable | Recruiting | NYU Langone Health | 1180 | 2026-04-22 | 2026-07-22 |
| ACT-based Parenting Program for Caregivers of Children With Hearing Loss Post-cochlear: A Pilot Randomised Controlled Trial ACT-based parenting program+usual care, Usual care - Hearing Loss, Stress | Not applicable | Not yet recruiting | Second Xiangya Hospital of Central South University | 64 | 2026-03-28 | 2026-03-17 |
| The COMParing App Support Strategies Study Introductory Coaching Session, Introductory Information Session, On-Demand Email or Text Support - Depression, Anxiety | Not applicable | Recruiting | University of Wisconsin, Madison | 688 | 2026-03-13 | 2026-10-29 |
| Weekly Dynamics of Psychopathological and Symptom Networks During Mindfulness-Based Interventions for Emotional Distress Mindfulness Intervention for Emotional Distress (self-guided version) - Depression, Anxiety, Emotional Disorders | Not applicable | Recruiting | Peking University | 500 | 2025-11-16 | 2026-04-27 |
| Clinical Outcomes of a Digital Mental Health Intervention for Moderate/Severe Depression and Anxiety BetterHelp - Depression, Anxiety, Mental Health Issue | Not applicable | Completed | Teladoc Health | 86 | 2025-10-06 | 2026-08-26 |
| Multidimensional Sleep Health Intervention to Optimize Concussion Recovery Sleep Intervention - Concussion (Diagnosis), Concussion, Mild Traumatic Brain Injury | Not applicable | Recruiting | University of Colorado, Denver | 54 | 2025-09-10 | 2026-06-18 |
| SUpport From PEeRs to Expand Access Study - Community Behavioral: Supported dCBT, Behavioral: Unsupported dCBT - Depression, Anxiety | Not applicable | Recruiting | University of California, Berkeley | 213 | 2025-08-18 | 2025-09-22 |
| Building Connections Treatment as Usual, Building Connections Intervention - Cancer Colorectal, Cancer Cervix | Not applicable | Recruiting | Massachusetts General Hospital | 3600 | 2025-08-07 | 2025-11-18 |
| Personalized Education and Pain Response in Chronic Pancreatitis Personalised education - Chronic Pancreatitis, Pain Syndrome | Not applicable | Not yet recruiting | Asian Institute of Gastroenterology, India | 114 | 2025-08-01 | 2025-07-30 |
| Developing Evidence-Based Cognitive Approaches to Improve Adjustment to Vision Loss Integrated Cognitive Behavioral Therapy (CBT) & Mindfulness Group Intervention for Adjustment to Vision Loss - Depression, Anxiety, Visual Impairment | Not applicable | Recruiting | The Chicago Lighthouse | 45 | 2025-07-14 | 2025-07-30 |
| Test of Target Engagement of Ambiguity Aversion Uncertainty-focused single session intervention, Maintaining a healthy lifestyle single session intervention - Intolerance of Uncertainty, Anxiety | Not applicable | Recruiting | Northwestern University | 140 | 2025-07-07 | 2026-05-26 |
| Acceptance and Commitment Therapy-based Intervention for Parents of a Child With Medical Complexity ACT-based intervention - Acceptance and Commitment Therapy, Child With Medical Complexity | Not applicable | Completed | The Hong Kong Polytechnic University | 24 | 2025-07-02 | 2026-09-16 |
| Effects of Exercıse on Chronotype, Sleep Qualıty and Depressıon Symptom Level in Unıversıty Students Exercise - Depression, Anxiety, Chronotype | Not applicable | Active not recruiting | Aydin Adnan Menderes University | 54 | 2025-06-18 | 2025-10-02 |
| Psychological Adjustment to Long-term (PAL) Physical Conditions: A Randomised Cross-over Feasibility Trial of a Self-guided App Orbi - Depression, Anxiety, Chronic Disease | Not applicable | Completed | King's College London | 58 | 2025-06-10 | 2026-08-07 |
| Just-In-Time Adaptive Interventions (JITAIs) in a Digital Mental Health Intervention for Middle-Aged and Older Adults With Chronic Pain Just-In-Time Adaptive Interventions (JITAIs), Wysa for Chronic Pain - Chronic Pain, Depression, Anxiety | Not applicable | Completed | Washington University School of Medicine | 773 | 2025-06-02 | 2026-11-06 |
| Sedentary Behavior and Depressive Symptoms Physical activity intervention, Standard of care - Depression, Anxiety | Not applicable | Recruiting | University of Sao Paulo General Hospital | 84 | 2025-06-01 | 2025-07-25 |
| Generative Artificial Intelligence Intervention and Individual Psychological Counseling on Emotional Distress in Young Adults Generative Artificial Intelligence Intervention, Individual Psychological Counseling - Depression, Anxiety | Not applicable | Completed | Central University of Finance and Economics, China | 222 | 2025-05-20 | 2026-05-28 |
| 'Nurture and Play' - a Pilot Study Nurture and Play (NnP) - Depression, Anxiety, Intervention | Not applicable | Completed | Center for Clinical Research and Prevention | 20 | 2025-05-15 | 2026-10-22 |
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Anxiety Disorders (218) · Depression (218) · Psychological Well-Being (15) · Stress Disorders, Post-Traumatic (13) · Sleep Initiation and Maintenance Disorders (10) · Motor Activity (8) · Stress, Psychological (8) · Neoplasms (6) · Breast Neoplasms (5) · COVID-19 (5) · Chronic Pain (5) · Obesity (5) · Cognitive Dysfunction (4) · Fatigue (4) · Mental Disorders (4)
Behavioral Symptoms (217) · Behavior (216) · Mental Disorders (214) · Pathological Conditions, Signs and Symptoms (35) · Nervous System Diseases (24) · Signs and Symptoms (24) · Neurologic Manifestations (16) · Pathologic Processes (15) · Personal Satisfaction (15) · Stress Disorders, Traumatic (15) · Trauma and Stressor Related Disorders (15) · Urogenital Diseases (14) · Neoplasms (13) · Sleep Wake Disorders (11) · Dyssomnias (10)
Cognitive Behavioral Therapy (7) · Mindfulness (6) · Therapeutics (6) · Mental Health (4) · Exercise (3) · Standard of Care (3) · Acceptance and Commitment Therapy (2) · Crisis Intervention (2) · Transcranial Magnetic Stimulation (2) · Acupuncture Therapy (1) · Aging (1) · Anesthesia, General (1) · Bibliotherapy (1) · Caregivers (1) · Cholecalciferol (1)
Chinese University of Hong Kong (4) · Stanford University (4) · Massachusetts General Hospital (3) · Montana State University (3) · Northwestern University (3) · The Hong Kong Polytechnic University (3) · University of California, Irvine (3) · University of Colorado, Denver (3) · University of Manitoba (3) · University of Wisconsin, Madison (3) · Harvard University (2) · Peking University (2) · Rutgers, The State University of New Jersey (2) · Sangath (2) · The University of Hong Kong (2)
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Leslie E Roos, PhD (3) · Fiona Yan-Yee Ho (2) · Lianne Tomfohr-Madsen, PhD (2) · Stephen M Schueller, PhD (2) · Vikram Patel, PhD (2) · Xinghua Liu (2) · Abby L. Cheng, MD, MPHS (1) · Adrian Aguilera, PhD (1) · Adrian Lopresti, PhD (1) · Alejandro Martinez Rodriguez, Assistant (1) · Alethea Desrosiers (1) · Alexandra Adams, MD, Ph.D (1) · Alexandra L Terrill, PhD (1) · Alexandru Burlacu, MD, PhD (1)
PMID 10928201, PMID 14672796, PMID 16427171, PMID 17364516, PMID 18243894, PMID 19812460, PMID 20686627, PMID 21266141, PMID 22353021, PMID 22591515, PMID 22671966, PMID 22909316, PMID 23647804, PMID 25897757, PMID 28220089, PMID 28409729, PMID 29504794, PMID 29704969, PMID 3058677, PMID 30678679, PMID 31789601, PMID 3200278, PMID 32838678, PMID 33009852, PMID 33343425, PMID 33355633, PMID 33413109, PMID 33933665, PMID 33949959, PMID 33988517, PMID 34040886, PMID 34051772, PMID 34194374, PMID 34231203, PMID 34586075, PMID 35025538, PMID 35027938, PMID 35576997, PMID 35712448, PMID 35782290, PMID 36064436, PMID 36384735, PMID 36459760, PMID 36471891, PMID 36576188, PMID 36810120, PMID 36895006, PMID 37046290, PMID 37071612, PMID 37310781
2019 (2), P30CA012197 (2), K23HD113845 (1), K23MH120324 (1), K43TW011586 (1), P20GM104417 (1), R00AA030601 (1), R01CA258311 (1), R01MH116829 (1), R01MH124718 (1), R01MH126664 (1), R01MH131025 (1), R01MH131698 (1), R01MH131989 (1), R01MH133266 (1)