57 completed, 3 unknown, 2 recruiting, 2 withdrawn. 23 Not applicable, 13 Phase 2, 11 Phase 3, 8 Phase 1, 3 Phase 4.
Follow Cytomegalovirus Retinitis: new trials by email Literature Review of Cytomegalovirus Retinitis trials Research Report on Cytomegalovirus Retinitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Safety and Efficacy of Autologous LB-DTK-CMV in Patients With Antiviral-Resistant and Refractory Cytomegalovirus Retinitis. LB-DTK-CMV - CMV Retinitis | Not applicable | Recruiting | LucasBio | 5 | 2026-04-27 | 2026-07-01 |
| Clinical Study of High Concentration Ganciclovir Eye Drops in the Treatment of Cytomegalovirus Retinitis 2% Ganciclovir Eye Drops - Cytomegalovirus Retinitis, Ganciclovir Eye Drops | Early Phase 1 | Recruiting | Tianjin Medical University | 15 | 2023-07-01 | 2023-06-23 |
| Deep Learning-based System and AIDS-related Cytomegalovirus Retinitis Cytomegalovirus Retinitis | Completed | Kuifang Du | 50 | 2021-04-01 | 2021-07-21 | |
| Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care: - Adenovirus, Anesthesia | Completed | Daniel Benjamin | 3520 | 2011-11-01 | 2023-09-06 | |
| Efficacy of Elevated CD4 Counts on CMV Retinitis Acquired Immunodeficiency Syndrome, Cytomegalovirus Retinitis | Completed | National Eye Institute (NEI) | 15 | 2004-07-01 | 2008-03-04 | |
| Pharmacokinetics of Cidofovir During Continuous Venovenous Hemofiltration Cidofovir pharmacokinetics - Cytomegalovirus Retinitis, Acute Renal Failure | Phase 4 | Completed | Medical University of Vienna | 1 | 2002-03-01 | 2013-06-05 |
| Longitudinal Study of Ocular Complications of AIDS (LSOCA) HIV Infections, Acquired Immunodeficiency Syndrome | Completed | Johns Hopkins Bloomberg School of Public Health | 2392 | 1998-08-01 | 2015-06-12 | |
| Studies of Ocular Complications of AIDS (SOCA)--Ganciclovir-Cidofovir CMV Retinitis Trial (GCCRT) Ganciclovir implant and oral ganciclovir, Cidofovir intravenous - Cytomegalovirus Retinitis, HIV Infections | Phase 3 | Completed | Johns Hopkins Bloomberg School of Public Health | 61 | 1997-05-01 | 2016-03-14 |
| Immune Activity Against CVM Retinitis Acquired Immunodeficiency Syndrome, Cytomegalovirus Retinitis | Completed | National Eye Institute (NEI) | 15 | 1997-02-01 | 2008-03-04 | |
| A Comparison of Valganciclovir and Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes Valganciclovir, Ganciclovir - Cytomegalovirus Retinitis, HIV Infections | Phase 3 | Completed | Hoffmann-La Roche | 1997-01-01 | 2017-05-17 | |
| Studies of the Ocular Complications of AIDS (SOCA)--Monoclonal Antibody CMV Retinitis Trial (MACRT) MSL-109, Placebo - HIV Infections, Cytomegalovirus Retinitis | Phase 2 / Phase 3 | Completed | Johns Hopkins Bloomberg School of Public Health | 209 | 1995-09-01 | 2015-11-17 |
| Phase II Randomized Study of Cidofovir for Peripheral Cytomegalovirus Retinitis cidofovir - Cytomegalovirus Retinitis, Acquired Immunodeficiency Syndrome | Phase 2 | Completed | National Center for Research Resources (NCRR) | 90 | 1995-03-01 | 2005-06-24 |
| Studies of the Ocular Complications of AIDS (SOCA)--HPMPC Peripheral CMV Retinitis Trial (HPCRT) Cidofovir - HIV Infections, CMV Cytomegalovirus Retinitis | Phase 2 / Phase 3 | Completed | Johns Hopkins Bloomberg School of Public Health | 64 | 1994-04-01 | 2015-11-17 |
| Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT) Ganciclovir, Foscarnet - HIV Infections, Acquired Immunodeficiency Syndrome | Phase 3 | Completed | Johns Hopkins Bloomberg School of Public Health | 279 | 1992-12-01 | 2015-09-14 |
| Ganciclovir Implant Study for Cytomegalovirus Retinitis Sustained-Release Intraocular Drug Delivery System - HIV Infections, Acquired Immunodeficiency Syndrome | Phase 3 | Completed | National Eye Institute (NEI) | 1992-10-01 | 2009-09-17 | |
| Studies of the Ocular Complications of AIDS (SOCA)--Foscarnet-Ganciclovir CMV Retinitis Trial (FGCRT) Foscarnet, Ganciclovir - HIV Infections, Cytomegalovirus Retinitis | Phase 3 | Completed | Johns Hopkins Bloomberg School of Public Health | 234 | 1990-03-01 | 2015-10-22 |
| A Study to Evaluate the Effects of Stopping Maintenance Therapy for Cytomegalovirus (CMV) Retinitis After Effective Anti-HIV Therapy Cytomegalovirus Retinitis, HIV Infections | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 75 | 2008-07-30 | ||
| A Study of Ganciclovir in the Treatment of Cytomegalovirus of the Eyes Ganciclovir - Cytomegalovirus Retinitis, HIV Infections | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 25 | 2021-11-04 | |
| A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Who Cannot Use Ganciclovir Foscarnet sodium - Cytomegalovirus Retinitis, HIV Infections | Phase 2 | Withdrawn | National Institute of Allergy and Infectious Diseases (NIAID) | 2021-11-04 | ||
| Suppression of Cytomegalovirus Retinitis Utilizing High Dose Intravenous Acyclovir and Oral Zidovudine in Patients With AIDS Zidovudine, Acyclovir - Cytomegalovirus Retinitis, HIV Infections | Not applicable | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 25 | 2021-11-02 |
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HIV Infections (57) · Acquired Immunodeficiency Syndrome (46) · Retinitis (36) · Cytomegalovirus Infections (32) · Multiple Acyl Coenzyme A Dehydrogenase Deficiency (30) · AIDS-Related Opportunistic Infections (25) · Neutropenia (2) · Acute Kidney Injury (1) · Adenoviridae Infections (1) · Anxiety Disorders (1) · Arrhythmias, Cardiac (1) · Autistic Disorder (1) · Autoimmune Diseases (1) · Bipolar Disorder (1)
DNA Virus Infections (64) · Eye Diseases (64) · Eye Infections (64) · Eye Infections, Viral (64) · Herpesviridae Infections (64) · Virus Diseases (64) · Infections (63) · Retinal Diseases (63) · Urogenital Diseases (62) · Genital Diseases (61) · Immune System Diseases (61) · RNA Virus Infections (61) · Blood-Borne Infections (60) · Communicable Diseases (60) · Immunologic Deficiency Syndromes (60)
Ganciclovir (27) · Foscarnet (13) · Cidofovir (10) · Probenecid (5) · fomivirsen (4) · sevirumab (4) · Valganciclovir (3) · Zidovudine (3) · sargramostim (2) · Acyclovir (1) · Alfentanil (1) · Amikacin (1) · Aminocaproic Acid (1) · Antibodies, Monoclonal (1) · Bosentan (1)
National Institute of Allergy and Infectious Diseases (NIAID) (21) · Hoffmann-La Roche (9) · Johns Hopkins Bloomberg School of Public Health (6) · Astra USA (4) · Ionis Pharmaceuticals, Inc. (4) · Gilead Sciences (3) · National Eye Institute (NEI) (3) · Roche Global Development (3) · Agouron Pharmaceuticals (1) · American National Red Cross (1) · Chiron Corporation (1) · Daniel Benjamin (1) · Kuifang Du (1) · LucasBio (1) · Medical University of Vienna (1)
United States (51) · Canada (6) · China (2) · United Kingdom (2) · Austria (1) · Israel (1) · Puerto Rico (1) · Singapore (1) · South Korea (1)
Douglas Jabs, MD (2) · Hardy WD (2) · MA Jacobson (2) · Borucki M (1) · Brosgart C (1) · C Crumpacker (1) · CA Benson (1) · CS Crumpacker (1) · Chao Chen (1) · Chi Hornik, PharmD (1) · Craig C (1) · Curtis Meinert, PhD (1) · Dankner W (1) · David V. Weinberg (1) · Doug A Jabs, MD (1)
PMID 31042791, PMID 11919489, PMID 12232843, PMID 12559647, PMID 15498605, PMID 16192248, PMID 24614374, PMID 24949994, PMID 26039810, PMID 26926644, PMID 27522443, PMID 28137820, PMID 28290120, PMID 28779462, PMID 29084742, PMID 29271816, PMID 29435949, PMID 29677389, PMID 30790601, PMID 31317556, PMID 31548185, PMID 31814149, PMID 32324313, PMID 32497307, PMID 33029806, PMID 33903114, PMID 34302290, PMID 35370711, PMID 35491971, PMID 41247430, PMID 9400786
U10EY008057 (3), U01AI027668 (1)