49 completed, 6 unknown, 2 recruiting, 2 withdrawn. 25 Not applicable, 13 Phase 1, 8 Phase 2, 5 Phase 3, 4 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 25 | Completed 23, Unknown 2 |
| Phase 1 | 13 | Completed 11, Unknown 1, Withdrawn 1 |
| Phase 2 | 8 | Completed 7, Withdrawn 1 |
| Phase 3 | 5 | Completed 4, Terminated 1 |
| Phase 4 | 4 | Completed 4 |
Follow Multiple Acyl Coenzyme A Dehydrogenase Deficiency: new trials by email Literature Review of Multiple Acyl Coenzyme A Dehydrogenase Deficiency trials Research Report on Multiple Acyl Coenzyme A Dehydrogenase Deficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Natural History of MADD Multiple Acyl-CoA Dehydrogenase Deficiency | Recruiting | Icahn School of Medicine at Mount Sinai | 50 | 2026-10-01 | 2026-09-16 | |
| Topical Ganciclovir Versus Systemic Aciclovir in the Treatment of Herpetic Keratitis Acyclovir 400 MG, Ganciclovir (GCV) - Herpetic Keratitis | Not applicable | Completed | Al-Azhar University | 20 | 2024-10-01 | 2025-01-03 |
| Ganciclovir Resistant/Refractory Cytomegalovirus Infection in SOT Recipients and HSCT Patients Cytomegalovirus Infections | Recruiting | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 100 | 2023-06-19 | 2026-06-15 | |
| Selective Screening of Children for Hereditary Metabolic Diseases by Tandem Mass Spectrometry in Kazakhstan Obtaining Dry Blood Spots From Healthy Newborns (Aged 1-7 Days), Obtaining Dry Blood Spots From Healthy Children Aged 8 Days - 7 Years, Obtaining Dry Blood Spots From Healthy Children Aged 8-18 Years - Propionic/Methylmalonic Acidemias, Maple Syrup Urine Disease | Unknown | West Kazakhstan Medical University | 2250 | 2022-10-03 | 2023-06-18 | |
| Nexus of Risk: Sexual Assault, Alcohol Use, and Risky Sex Among College Women Ecological Momentary Intervention - Sexual Assault, Substance Use | Not applicable | Completed | University of New Mexico | 183 | 2018-10-01 | 2024-04-02 |
| (Val)Ganciclovir TDM in Transplant Recipients Ganciclovir, Valganciclovir - Cytomegalovirus Infections | Unknown | University Medical Center Groningen | 100 | 2018-05-25 | 2019-10-10 | |
| Observational Study Comparing the Efficacy of Ganciclovir as a Function of Blood Exposure to the Drug During a Curative or Preemptive Treatment Therapeutic Drug Monitoring - Solid Organ Transplantation | Unknown | Rennes University Hospital | 138 | 2017-02-21 | 2023-04-12 | |
| Study of Cytolytic Viral Activation Therapy (CVAT) for Recurrent/Metastatic Nasopharyngeal Carcinoma Gemcitabine, Valproic acid, Valganciclovir - Nasopharyngeal Carcinoma | Phase 1 | Unknown | Chang Gung Memorial Hospital | 18 | 2016-05-01 | 2016-05-16 |
| Fat and Sugar Metabolism During Exercise in Patients With Metabolic Myopathy Sugar - Metabolism, Inborn Errors, Lipid Metabolism, Inborn Errors | Not applicable | Unknown | Copenhagen University Hospital, Rigshospitalet | 60 | 2016-01-01 | 2019-10-16 |
| High-dose Intravitreal Injection of Ganciclovir for the Treatment of CMVR in HIV-negative Patients Ganciclovir - Infection Viral, Uveitis, Posterior | Not applicable | Completed | Aier School of Ophthalmology, Central South University | 33 | 2014-01-01 | 2018-07-26 |
| CMV Antiviral Prevention Strategies in D+R-Liver Transplants ("CAPSIL") Valganciclovir - Cytomegalovirus Infection | Phase 4 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 205 | 2012-10-29 | 2021-08-26 |
| Topical Administration of 0.15% Ganciclovir Gel for CMV Anterior Uveitis / Endotheliitis Ganciclovir - Cytomegalovirus Anterior Segment Infection, Anterior Uveitis | Not applicable | Completed | Singapore National Eye Centre | 29 | 2012-07-01 | 2015-11-18 |
| Cytomegalovirus Control in Critical Care Valaciclovir/Aciclovir, Valganciclovir/Ganciclovir - Critical Illness | Phase 2 | Completed | University Hospital Birmingham NHS Foundation Trust | 124 | 2012-01-01 | 2015-01-12 |
| Study Comparing Valganciclovir Versus Ganciclovir in Patients Following Allogeneic Stem Cell Transplantation Valganciclovir, Ganciclovir - Allogeneic Stem Cell Transplantation | Phase 3 | Terminated | Pierrel Research Europe GmbH | 212 | 2010-09-01 | 2012-12-10 |
| Ganciclovir 0,15% Ophthalmic Gel in the Treatment of Adenovirus Keratoconjuntivitis Ganciclovir, Artificial tear - Conjunctivitis, Viral, Adenoviridae Infections | Not applicable | Completed | Federal University of São Paulo | 33 | 2009-08-01 | 2011-05-06 |
| Valganciclovir for Treatment of Cytomegalovirus Infection in Solid Organ Transplant Patients Single arm (ganciclovir and valganciclovir) - Cytomegalovirus Infection | Phase 4 | Completed | Salvador Gil-Vernet | 21 | 2004-03-01 | 2011-09-21 |
| Valganciclovir in Congenital CMV Infants Valganciclovir, Ganciclovir - Cytomegalovirus Infections | Phase 1 / Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 24 | 2002-07-01 | 2011-02-07 |
| Neonatal CMV-Ganciclovir Follow-up Study Cytomegalovirus Infections | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 8 | 2001-09-01 | 2011-08-12 | |
| Prophylaxis With Ganciclovir Improves Graft Survival in Renal Allograft Recipients Ganciclovir - DNA Virus Infection, Herpesviridae Infections | Phase 4 | Completed | Lower Saxony Center for Nephrology | 150 | 2000-08-01 | 2006-09-13 |
| Preventing Cytomegalovirus (CMV) Organ Damage With Valganciclovir in People With HIV Valganciclovir - Cytomegalovirus Infections, HIV Infections | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 350 | 2000-08-01 | 2021-11-01 |
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HIV Infections (40) · Cytomegalovirus Infections (39) · Acquired Immunodeficiency Syndrome (36) · Cytomegalovirus Retinitis (30) · Retinitis (25) · AIDS-Related Opportunistic Infections (20) · Carnitine palmitoyl transferase 2 deficiency (2) · Colitis (2) · Medium chain acyl CoA dehydrogenase deficiency (2) · Metabolism, Inborn Errors (2) · Neoplasm Metastasis (2) · Systemic carnitine deficiency (2) · Trifunctional Protein Deficiency With Myopathy And Neuropathy (2) · VLCAD deficiency (2)
Amino Acid Metabolism, Inborn Errors (60) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (60) · Genetic Diseases, Inborn (60) · Metabolic Diseases (60) · Mitochondrial Diseases (60) · Nutritional and Metabolic Diseases (60) · Metabolism, Inborn Errors (58) · Infections (51) · Virus Diseases (50) · DNA Virus Infections (49) · Herpesviridae Infections (48) · Blood-Borne Infections (40) · Communicable Diseases (40) · Genital Diseases (40) · Immune System Diseases (40)
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PMID 38700045, PMID 39807668, PMID 15498605, PMID 19632953, PMID 19738014, PMID 22331114, PMID 23665863, PMID 26416517, PMID 28437539, PMID 29377953, PMID 30526535, PMID 30990523, PMID 31492716, PMID 32286644, PMID 32726431, PMID 38283151
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