225 completed, 41 unknown, 22 withdrawn, 19 recruiting. 79 Not applicable, 65 Phase 3, 57 Phase 2, 51 Phase 4, 34 Phase 1.
Follow Eye Infections: new trials by email Literature Review of Eye Infections trials Research Report on Eye Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery Moxifloxacin, Placebo - Endophthalmitis | Phase 2 / Phase 3 | Not yet recruiting | Jason Ahee, M.D. | 60000 | 2027-06-01 | 2026-09-15 |
| Fluorometholone Study Adjunctive Topical Fluorometholone (FML) 0.1%, Standard Topical Antibiotic Therapy - Keratitis Bacterial, Corneal Ulcer (Diagnosis) | Phase 2 | Not yet recruiting | Vishal Jhanji | 174 | 2026-10-31 | 2026-06-10 |
| Vitrectomy Combined With Povidone-Iodine Vitreous Irrigation for Infectious Endophthalmitis Povidone-iodine intravitreal irrigation with povidone-iodine containing 0.0025% available iodine, BSS intravitreal irrigation solution - Endophthalmitis, Infectious Endophthalmitis | Not applicable | Not yet recruiting | Beijing Tongren Hospital | 38 | 2026-10-30 | 2026-10-22 |
| Evaluation of the Impact of Oral Ivermectin on Musca Sorbens Flies, Putative Vector of Trachoma Ivermectin - Survival of Flies Developing in Faecal Samples | Phase 4 | Not yet recruiting | London School of Hygiene and Tropical Medicine | 12 | 2026-07-01 | 2026-06-18 |
| Expanding Access to Preventive Chemotherapy Among Mobile and Migrant Populations Modified Mass Administration of Medicines Strategy, Albendazole 400 mg, Praziquantel 40 mg/kg - Onchocerciasis (River Blindness), Schistosomiasis | Not applicable | Recruiting | Uwemedimo Friday Ekpo | 5760 | 2026-07-01 | 2026-07-16 |
| Safety and Efficacy of SUM-191 for Patients With Bacterial Conjunctivitis SUM-191, Placebo - Bacterial Conjunctivitis | Phase 1 / Phase 2 | Recruiting | Senju USA, Inc. | 426 | 2026-06-25 | 2026-06-30 |
| Evaluation of Safety and Efficacy of Autologous LB-DTK-CMV in Patients With Antiviral-Resistant and Refractory Cytomegalovirus Retinitis. LB-DTK-CMV - CMV Retinitis | Not applicable | Recruiting | LucasBio | 5 | 2026-04-27 | 2026-07-01 |
| Efficacy of EPD-09-25 for Eyelid Hygiene Before and After Eye Surgery. EPD Eyelid wipes - Cataract Surgery, Ocular Infections | Not applicable | Not yet recruiting | VISUfarma SpA | 100 | 2026-04-01 | 2026-02-20 |
| Follow-up Compliance for Corneal Ulcer Patients With SMS Reminder SMS reminder - Corneal Ulcer | Not applicable | Recruiting | Seva Canada Society | 310 | 2026-02-23 | 2026-05-12 |
| RESTORE: Comparing Two Approaches to Repeat TT Surgery Performed by Integrated Eye Care Workers (IECWs) B-RAP, BLTR - Trachoma, Eye Diseases | Not applicable | Recruiting | University of North Carolina, Chapel Hill | 1000 | 2026-01-13 | 2026-04-13 |
| Targeting Immunosuppressive Treatment for Non-infectious Uveitis Using Aqueous Humor Cytokine Profiles to improve clinical practice in treatment of non-infective uveitis - Uveitis Posterior Non-Infectious, Inflammation Eye | Not applicable | Active not recruiting | University of Milan | 220 | 2025-11-15 | 2025-12-03 |
| Retrospective Chart Review of Patients With Acanthamoeba Keratitis Who Have Received 0.8 mg/mL Polihexanide as Part of the "Medicines in Special Situations" (Medicamentos en Situaciones Especiales) Program in Spain. PHMB 0.08% - Acanthamoeba Keratitis | Completed | SIFI SpA | 23 | 2025-10-30 | 2026-06-22 | |
| Clinical Study of Intrastromal Anti-VEGF Injection for Corneal Neovascularization. Intrastromal anti-VEGF injection and topical antiviral eye drops, Conventional antiviral topical ocular drops. - Herpes Simplex Keratitis, Corneal Neovascularization | Phase 1 / Phase 2 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 100 | 2025-10-01 | 2026-01-09 |
| Intrastromal Moxifloxacin as an Adjunctive Therapy in Recalcitrant Bacterial Keratitis Intrastromal moxifloxacin injection plus standard topical moxifloxacin therapy, Standard topical moxifloxacin therapy alone - Bacterial Keratitis, Recalcitrant Infectious Keratitis | Not applicable | Recruiting | Minia University | 60 | 2025-10-01 | 2026-09-10 |
| Fungal Ulcer Treatment Augmented With Natamycin and Cyclosporine A Cyclosporine A, Placebo Comparator: Placebo - Fungal Keratitis, Corneal Ulcer | Phase 3 | Recruiting | University of California, San Francisco | 150 | 2025-09-01 | 2026-06-05 |
| Demographics and Clinical Characteristics of Ocular Inflammatory Diseases in Singapore No Intervention: Observational Cohort - Uveitis, Scleritis and Episcleritis | Active not recruiting | Singapore National Eye Centre | 200 | 2025-08-19 | 2025-09-16 | |
| Effects of Two Different Eye Care Practices on Eye Complications in Mechanically Ventilated Intensive Care Patients Control Group: Standard Eye Care Group, Intervention Group 1: Eye Care Using an Eye Care Kit, Intervention Group 2: Eye Care According to an Eye Care Protocol - Eye Care, Nursing Care | Not applicable | Recruiting | Istanbul Saglik Bilimleri University | 156 | 2025-07-01 | 2026-01-29 |
| Trachoma Elimination Study by Focused Antibiotic (TESFA) Azithromycin mass treatment, Azithromycin targeted treatment - Trachoma | Phase 4 | Withdrawn | Emory University | 2025-06-01 | 2025-07-16 | |
| Efficacy of Fusidic Acid 1% in the Treatment of Bacterial Conjunctivitis Fusidic Acid 1%, Placebo - Bacterial Conjunctivitis | Phase 3 | Recruiting | Baxis Pharmaceuticals, Inc. | 400 | 2025-03-21 | 2026-03-17 |
| Diagnosing Corneal Infection Corneal impression membrane (Millicell Cell Culture Insert, 12mm, hydrophilic PTFE 0.4µm (PICM01250)) - Corneal Ulcer (Diagnosis) | Withdrawn | University of Edinburgh | 2025-02-01 | 2026-02-27 |
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Cytomegalovirus Retinitis (64) · Endophthalmitis (58) · HIV Infections (57) · Corneal Ulcer (55) · Acquired Immunodeficiency Syndrome (46) · Trachoma (38) · Retinitis (37) · Conjunctivitis, Bacterial (35) · Cytomegalovirus Infections (32) · Multiple Acyl Coenzyme A Dehydrogenase Deficiency (32) · AIDS-Related Opportunistic Infections (25) · Keratitis (19) · Conjunctivitis (17) · Conjunctivitis, Viral (14)
Infections (331) · Eye Diseases (329) · Corneal Diseases (116) · Conjunctival Diseases (101) · Bacterial Infections and Mycoses (100) · Virus Diseases (97) · Eye Infections, Viral (92) · Bacterial Infections (83) · DNA Virus Infections (82) · Conjunctivitis (81) · Herpesviridae Infections (80) · Eye Infections, Bacterial (79) · Retinal Diseases (71) · Urogenital Diseases (70)
Azithromycin (32) · Ganciclovir (30) · Moxifloxacin (19) · Foscarnet (13) · Cidofovir (10) · Ivermectin (10) · Ophthalmic Solutions (10) · Gatifloxacin (9) · Lubricant Eye Drops (7) · besifloxacin (7) · Albendazole (6) · Acyclovir (5) · Povidone-Iodine (5) · Probenecid (5) · moxidectin (5)
University of California, San Francisco (24) · National Institute of Allergy and Infectious Diseases (NIAID) (21) · Alcon Research (9) · Hoffmann-La Roche (9) · National Eye Institute (NEI) (9) · Bausch & Lomb Incorporated (8) · Johns Hopkins University (8) · Laboratoires Thea (8) · London School of Hygiene and Tropical Medicine (7) · Federal University of São Paulo (6) · Johns Hopkins Bloomberg School of Public Health (6) · Laboratorios Sophia S.A de C.V. (5) · Merck Sharp & Dohme LLC (5) · NicOx (5) · University of Campinas, Brazil (5)
United States (131) · Brazil (21) · China (16) · France (16) · United Kingdom (15) · Canada (14) · Egypt (14) · India (14) · Ethiopia (11) · Italy (11) · Germany (10) · Mexico (6) · Poland (6) · Spain (6) · Taiwan (6)
Tom Lietman, MD (6) · Thomas M Lietman, MD (3) · Bala Ambati (2) · Catherine Oldenburg, ScD, MPH (2) · Douglas Jabs, MD (2) · Elodie Lebas, RN (2) · Emily Gower, PhD (2) · Emma Harding-Esch (2) · Fung-Rong Hu, MD (2) · Gerami D Seitzman, MD (2) · Hardy WD (2) · Jennifer Rose-Nussbaumer, MD (2)
PMID 31042791, PMID 31589610, PMID 32557558, PMID 21681652, PMID 22953007, PMID 34483270, PMID 35024776, PMID 10832689, PMID 11285665, PMID 11345344, PMID 11520759, PMID 11673290, PMID 11919489, PMID 12095806, PMID 12131029, PMID 12232843, PMID 12386069, PMID 12515932, PMID 12559647, PMID 14765348, PMID 15355406, PMID 15498605, PMID 15642810, PMID 15829742, PMID 16192248, PMID 16257309, PMID 16575115, PMID 16631047, PMID 16905024, PMID 16926355, PMID 17258535, PMID 17420365, PMID 17531690, PMID 17583820, PMID 17652708, PMID 17657018, PMID 17760640, PMID 17996212, PMID 18204773, PMID 18245962, PMID 18374301, PMID 18608899, PMID 18677274, PMID 18829631, PMID 19097643, PMID 19107048, PMID 19107050, PMID 19108788, PMID 19234342, PMID 19329003
U10EY008057 (3), 5UG1EY030833 (2), R01AI048789 (2), U10EY018573 (2), 1UG1EY028088 (1), 1UG1EY036891 (1), 2016 (1), 2019 (1), 2023 (1), K23EY019881 (1), R01EY031033 (1), U01AI027668 (1), U10EY015114 (1), U10EY022584 (1), U10EY022880 (1)