Astra USA: Clinical Trials

9 completed, 1 unknown. 5 Not applicable, 2 Phase 1, 2 Phase 4, 1 Phase 3.

By phase and status

Phase	Trials	Status
Not applicable	5	Completed 4, Unknown 1
Phase 1	2	Completed 2
Phase 4	2	Completed 2
Phase 3	1	Completed 1

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
An Open Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies Foscarnet sodium - Herpes Simplex, HIV Infections	Not applicable	Completed	Astra USA			2005-06-24
The Pilot Study of Foscarnet Cream in the Treatment of Mucocutaneous Herpes Simplex Virus Infections in Immunocompromised Patients Unresponsive to Acyclovir Treatment Foscarnet sodium - Herpes Simplex, HIV Infections	Phase 1	Completed	Astra USA	12		2005-06-24
Safety and Efficacy of Intravenous Magnesium Sulfate in Modulating Changes in Symptoms and Divalent Cation Levels Associated With Foscavir Therapy: A Phase IV Randomized, Double-Blind, Placebo-Controlled, Cross-Over, Pilot Study Magnesium sulfate, Foscarnet sodium - Cytomegalovirus Infections, HIV Infections	Phase 4	Completed	Astra USA	12		2005-06-24
Phase III Multicenter, Open-Label, Randomized Trial of Induction Versus Induction Plus Maintenance Foscarnet ( Foscavir ) Therapy for Gastrointestinal CMV Disease Foscarnet sodium - HIV Infections, Gastrointestinal Diseases	Phase 3	Completed	Astra USA	145		2005-06-24
A Multicenter Study of Oral Versus Intravenous Hydration in AIDS Patients With CMV Retinitis Treated With Foscavir (Foscarnet Sodium) Foscarnet sodium - Cytomegalovirus Retinitis, HIV Infections	Phase 4	Completed	Astra USA	112		2005-06-24
An Open Study of Foscarnet Treatment First Episode CMV-Retinitis in AIDS Patients Foscarnet sodium - Cytomegalovirus Retinitis, HIV Infections	Not applicable	Completed	Astra USA			2005-06-24
A Study of Foscarnet Plus Ganciclovir in the Treatment of Cytomegalovirus of the Eye in Patients With AIDS Who Have Already Been Treated With Ganciclovir Foscarnet sodium, Ganciclovir - Cytomegalovirus Retinitis, HIV Infections	Phase 1	Completed	National Institute of Allergy and Infectious Diseases (NIAID)	30		2021-11-04
An Open, Multicenter Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies Foscarnet sodium - Herpes Simplex, HIV Infections	Not applicable	Completed	Astra USA			2005-06-24
A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Foscarnet sodium - Cytomegalovirus Retinitis, HIV Infections	Not applicable	Completed	Astra USA			2005-06-24
A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Who Have Not Had Success With Ganciclovir Foscarnet sodium - Cytomegalovirus Retinitis, HIV Infections	Not applicable	Unknown	Astra USA			2005-06-24

Conditions studied

Acquired Immunodeficiency Syndrome (10)  ·  HIV Infections (10)  ·  Cytomegalovirus Infections (7)  ·  AIDS-Related Opportunistic Infections (6)  ·  Cytomegalovirus Retinitis (5)  ·  Retinitis (5)  ·  Herpes Simplex (3)  ·  Multiple Acyl Coenzyme A Dehydrogenase Deficiency (2)  ·  Gastrointestinal Diseases (1)  ·  Hypocalcemia (1)  ·  Magnesium Deficiency (1)

Interventions

Foscarnet (10)  ·  Ganciclovir (1)  ·  Magnesium Sulfate (1)

Countries

United States (10)

Top investigators

Hardy WD (1)  ·  Jacobson MA (1)  ·  Wool GM (1)