10 completed, 1 unknown. 11 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Completed 10, Unknown 1 |
| Phase 2 | 2 | Completed 2 |
Follow Cytomegalovirus Retinitis: new trials by email Literature Review of Cytomegalovirus Retinitis trials Research Report on Cytomegalovirus Retinitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Studies of Ocular Complications of AIDS (SOCA)--Ganciclovir-Cidofovir CMV Retinitis Trial (GCCRT) Ganciclovir implant and oral ganciclovir, Cidofovir intravenous - Cytomegalovirus Retinitis, HIV Infections | Phase 3 | Completed | Johns Hopkins Bloomberg School of Public Health | 61 | 1997-05-01 | 2016-03-14 |
| A Comparison of Valganciclovir and Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes Valganciclovir, Ganciclovir - Cytomegalovirus Retinitis, HIV Infections | Phase 3 | Completed | Hoffmann-La Roche | 1997-01-01 | 2017-05-17 | |
| Studies of the Ocular Complications of AIDS (SOCA)--Monoclonal Antibody CMV Retinitis Trial (MACRT) MSL-109, Placebo - HIV Infections, Cytomegalovirus Retinitis | Phase 2 / Phase 3 | Completed | Johns Hopkins Bloomberg School of Public Health | 209 | 1995-09-01 | 2015-11-17 |
| Studies of the Ocular Complications of AIDS (SOCA)--HPMPC Peripheral CMV Retinitis Trial (HPCRT) Cidofovir - HIV Infections, CMV Cytomegalovirus Retinitis | Phase 2 / Phase 3 | Completed | Johns Hopkins Bloomberg School of Public Health | 64 | 1994-04-01 | 2015-11-17 |
| Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT) Ganciclovir, Foscarnet - HIV Infections, Acquired Immunodeficiency Syndrome | Phase 3 | Completed | Johns Hopkins Bloomberg School of Public Health | 279 | 1992-12-01 | 2015-09-14 |
| Ganciclovir Implant Study for Cytomegalovirus Retinitis Sustained-Release Intraocular Drug Delivery System - HIV Infections, Acquired Immunodeficiency Syndrome | Phase 3 | Completed | National Eye Institute (NEI) | 1992-10-01 | 2009-09-17 | |
| Studies of the Ocular Complications of AIDS (SOCA)--Foscarnet-Ganciclovir CMV Retinitis Trial (FGCRT) Foscarnet, Ganciclovir - HIV Infections, Cytomegalovirus Retinitis | Phase 3 | Completed | Johns Hopkins Bloomberg School of Public Health | 234 | 1990-03-01 | 2015-10-22 |
| A Treatment Protocol for the Use of Intravenous Ganciclovir in AIDS Patients With Immediately Sight-Threatening CMV Retinitis Ganciclovir - Cytomegalovirus Retinitis, HIV Infections | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 2008-09-30 | ||
| Valganciclovir in Patients With CMV Retinitis and AIDS Who Cannot Take Drugs by Injection Valganciclovir - Cytomegalovirus Retinitis, HIV Infections | Phase 3 | Unknown | Hoffmann-La Roche | 500 | 2005-06-24 | |
| A Randomized, Controlled Study of Intravenous Ganciclovir Therapy for Peripheral Cytomegalovirus Retinitis in Patients With AIDS Ganciclovir - Cytomegalovirus Retinitis, HIV Infections | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 180 | 2011-03-14 | |
| Phase III Ganciclovir +/- rGM-CSF for AIDS-Related CMV Retinitis Sargramostim, Ganciclovir - Cytomegalovirus Retinitis, HIV Infections | Phase 3 | Completed | Schering-Plough | 2005-06-24 |
HIV Infections (11) · Acquired Immunodeficiency Syndrome (5) · AIDS-Related Opportunistic Infections (3) · Cytomegalovirus Infections (3) · Multiple Acyl Coenzyme A Dehydrogenase Deficiency (3) · Retinitis (3) · Neutropenia (1)
Blood-Borne Infections (11) · Communicable Diseases (11) · DNA Virus Infections (11) · Eye Diseases (11) · Eye Infections (11) · Eye Infections, Viral (11) · Genital Diseases (11) · Herpesviridae Infections (11) · Immune System Diseases (11) · Immunologic Deficiency Syndromes (11) · Infections (11) · Lentivirus Infections (11) · RNA Virus Infections (11) · Retinal Diseases (11) · Retroviridae Infections (11)
Ganciclovir (6) · Cidofovir (2) · Foscarnet (2) · Valganciclovir (2) · Antibodies, Monoclonal (1) · sargramostim (1) · sevirumab (1)
Johns Hopkins Bloomberg School of Public Health (5) · Hoffmann-La Roche (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · National Eye Institute (NEI) (1) · Schering-Plough (1)
United States (6) · Canada (1) · Puerto Rico (1)
Douglas Jabs, MD (2) · Curtis Meinert, PhD (1) · Feinberg J (1) · Jabs D (1) · Spector SA (1)
PMID 31042791, PMID 11919489, PMID 12232843, PMID 12559647, PMID 9400786
U10EY008057 (2), U01AI027668 (1)