22 completed, 12 unknown, 6 recruiting, 2 terminated. 23 Not applicable, 1 Early Phase 1, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 23 | Completed 11, Unknown 7, Recruiting 2, Terminated 2, Withdrawn 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 1 | 1 | Completed 1 |
Follow Cornea: new trials by email Literature Review of Cornea trials Research Report on Cornea
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of GLP-1 Receptor Agonists on Dry Eye Disease in Patients With Type 2 Diabetes Mellitus and Obesity Dry Eye Disease (DED), Diabete Mellitus | Recruiting | Attikon Hospital | 100 | 2026-03-01 | 2026-06-02 | |
| Acute Ocular Effects of Cigarette Smoking Cigarette Smoking Exposure, No Smoking Exposure - Smoking ( Cigarette), Cornea | Recruiting | Istanbul University | 90 | 2026-02-15 | 2026-05-12 | |
| Corneal Topography and High Order Aberrations in Regular Contraceptive Pills Hormonal Contraception, Combined Oral Contraceptive (COC) - Cornea, Refraction Error | Completed | Elshimaa A.Mateen | 40 | 2024-10-01 | 2026-07-09 | |
| Euclid Phoenix Lens Design Trial 2 Euclid orthokeratology (standard coating), Euclid orthokeratology (enhanced coating) - Myopia, Cornea | Not applicable | Unknown | Euclid Systems Corporation | 50 | 2024-05-01 | 2024-04-30 |
| Safety of Topical Mesenchymal Stromal Cell Secretome for Ocular Surface Disease MSC Secretome Eye Drops - Mesenchymal Stromal Cells, Cornea | Early Phase 1 | Completed | University of Illinois at Chicago | 9 | 2024-01-24 | 2026-10-07 |
| INTACS for Non Ectatic With High Cylinder INTACS implantation - Cornea | Not applicable | Recruiting | Elshimaa A.Mateen | 50 | 2023-12-01 | 2025-05-14 |
| Euclid Phoenix Lens Design Trial Euclid orthokeratology MAX (current design), Euclid orthokeratology MAX Phoenix (new design) - Myopia, Cornea | Not applicable | Unknown | Euclid Systems Corporation | 30 | 2023-11-01 | 2024-04-29 |
| Comparison of Oral Isotretinoin vs Ancomparison of Oral Isotretinoin vs Antibiotics on Corneal Thickness With AV Oral Isotretinoin, Antibiotics - Cornea | Not applicable | Unknown | Superior University | 36 | 2023-11-01 | 2024-07-03 |
| OCT Vibrography for Biomechanical Properties of Tissues Optical imaging of the tissues - Cornea, Skin Diseases | Not applicable | Recruiting | Massachusetts General Hospital | 90 | 2023-08-19 | 2026-10-13 |
| MicroPulse Transscleral Laser Therapy and Its Short-term Impact on Ocular Surface conjunctival biopsy after micropulse transscleral laser therapy - Conjunctiva, Cornea | Not applicable | Completed | University Tunis El Manar | 15 | 2023-05-03 | 2024-04-09 |
| Influence of Silicone Hydrogel Contact Lens Neophyte Wear on Corneal Sensitivity Device: silicone hydrogel contact lens - Cornea | Not applicable | Completed | Daniela Nosch | 42 | 2023-04-08 | 2024-02-26 |
| Analysis of Topographic Corneal Parameters Oculus pentacam HR - Cornea | Completed | Minia University | 2694 | 2023-01-01 | 2024-01-24 | |
| Assessment of Corneal Topography and Densitometry in Rheumatoid Patients Cornea | Completed | Sohag University | 40 | 2023-01-01 | 2025-05-01 | |
| Assessment of an Automated Optical Coherence Tomography and Camera : Effectiveness of Vision-700 Vision-700 - Normal Subject, Glaucoma | Completed | Crystalvue Medical Coporation | 159 | 2022-09-01 | 2024-07-11 | |
| Evaluation Of Deep Anterior Lamellar Keratoplasty By Anterior Segment Ocular Coherence Tomography deep anterior lamellar keratoplasty - Keratoconus, Cornea | Unknown | Assiut University | 20 | 2022-05-01 | 2022-04-26 | |
| Efficiency of Intraoperative Optical Coherence Tomography (iOCT) Intraoperative Optical Coherence Tomography (iOCT) - Epiretinal Membrane, Glaucoma | Not applicable | Unknown | Somich, s.r.o. | 2 | 2022-05-01 | 2022-05-09 |
| Influence of Silicone Hydrogel Extended Contact Lens Wear on Corneal Sensitivity silicone hydrogel contact lens - Cornea | Not applicable | Completed | Daniela Nosch | 30 | 2022-04-01 | 2023-01-26 |
| fMRI and IVCM Cornea Microscopy of CXL in Keratoconus Pain, Postoperative, Pain, Chronic | Recruiting | Boston Children's Hospital | 60 | 2021-10-04 | 2025-12-19 | |
| A Prospective Trial of the Intelon BOSS(TM) System Brillouin Spectroscopy via BOSS System - Cornea, Lens Diseases | Not applicable | Terminated | Intelon Optics, Inc | 23 | 2021-07-24 | 2022-06-10 |
| Investigation in Corneal Sensation and Contact Lens Wear Tactile Esthesiometer Prototype, Liquid Jet Esthesiometer Prototype, Cochet Bonnet esthesiometer - Cornea, Sense Loss; Cornea | Not applicable | Completed | Daniela Nosch | 111 | 2021-05-01 | 2022-03-17 |
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Corneal Diseases (43) · Keratoconus (4) · Astigmatism (3) · Cataract (3) · Diabetes Mellitus (3) · Glaucoma (3) · Lens Diseases (2) · Myopia (2) · Refractive Errors (2) · Surgical Wound (2) · Acute Pain (1) · Blindness (1) · Chronic Pain (1) · Cigarette Smoking (1) · Corneal Dystrophies, Hereditary (1)
Eye Diseases (42) · Refractive Errors (5) · Endocrine System Diseases (3) · Glucose Metabolism Disorders (3) · Lens Diseases (3) · Metabolic Diseases (3) · Nutritional and Metabolic Diseases (3) · Ocular Hypertension (3) · Pathological Conditions, Signs and Symptoms (3) · Behavior (2) · Nervous System Diseases (2) · Neurologic Manifestations (2) · Pathologic Processes (2) · Retinal Diseases (2) · Signs and Symptoms (2)
Keratomileusis, Laser In Situ (2) · Anti-Bacterial Agents (1) · Biometry (1) · Carboxymethylcellulose Sodium (1) · Contraceptives, Oral, Combined (1) · Hormonal Contraception (1) · Nitrous Oxide (1) · Oxygen (1) · Phacoemulsification (1) · Photorefractive Keratectomy (1) · Tomography, Optical Coherence (1) · Watchful Waiting (1) · Weights and Measures (1)
Daniela Nosch (3) · Assiut University (2) · Elshimaa A.Mateen (2) · Euclid Systems Corporation (2) · Istanbul University (2) · Massachusetts General Hospital (2) · Moorfields Eye Hospital NHS Foundation Trust (2) · Optovue (2) · University of Illinois at Chicago (2) · Attikon Hospital (1) · Augenabteilung Allgemeines Krankenhaus Linz (1) · Boston Children's Hospital (1) · Carl Zeiss Meditec, Inc. (1) · Crystalvue Medical Coporation (1) · Federal University of São Paulo (1)
United States (12) · Egypt (4) · China (3) · Switzerland (3) · Austria (2) · Taiwan (2) · Turkey (Türkiye) (2) · Brazil (1) · Czechia (1) · Greece (1) · Italy (1) · Pakistan (1) · Tunisia (1) · United Kingdom (1)
Ali R Djalilian, MD (2) · Charlotte E Joslin, OD, PhD (2) · Daniela Nosch, PhD (2) · Seok-Hyun Yun, PhD (2) · AYong Yu, MD.PhD. (1) · Ahmed Abdelghany, professor (1) · Dalia M El-Sebity, Ass.prof. (1) · Daniela S Nosch, PhD (1) · Elmer Y Tu, MD (1) · Elshimaa A.Mateen, Doctor (1) · Eric A Moulton, OD PhD (1) · I-Chia Liang (1) · Jing Li (1) · Jun Yang (1) · Kemal Turgay Ozbilen, M.D. (1)
PMID 18642207, PMID 27409470, PMID 32738875, PMID 33620373, PMID 34868671, PMID 37658603, PMID 39073343, PMID 42310410
1UG3EY031809-01 (1)