Corneal Topography and High Order Aberrations in Women on Regular Contraceptive Pills
| Registry | NCT07693673 |
|---|---|
| Status | Completed |
| Study type | Observational |
| Enrollment | 40 (Actual) |
| Sponsor | Elshimaa A.Mateen (Other) |
| Conditions | Cornea, Refraction Error |
| Interventions | Hormonal Contraception, Combined Oral Contraceptive (COC) (Other, drug) |
| Dates | start 2024-10-01, primary completion 2026-01-30, completion 2026-03-30, first posted 2026-07-09, last updated 2026-07-09 |
| Locations | 1 site in Egypt |
Related Papers Related Patents Related Grants Related Experts
All trials for Cornea All trials for Refraction Error All trials of Hormonal Contraception All trials of Combined Oral Contraceptive (COC)
Effect of regular usage of contraceptive pills on corneal topography and corneal high-order aberrations
Comparing corneal topographic changes and corneal high-order aberrations for women planning to use oral contaceptive pills before and after the usage of the pills
| Arm | Type | Interventions | Description |
|---|---|---|---|
| Oral contraceptive pills users | Other: Hormonal Contraception; Drug: Combined Oral Contraceptive (COC) |
Sex: Female, ages: 18 Years to 40 Years, accepts healthy volunteers
Inclusion Criteria: * Female participants aged 18-40 years. * Prescribed combined oral contraceptive pills as part of routine gynecological care. * Willing to undergo corneal topography/tomography before starting treatment and after 1 year. * No previous history of corneal disease or ocular surgery. * Able to provide informed consent. Exclusion Criteria: * Keratoconus or suspected corneal ectasia. * Corneal opacity, dystrophy, degeneration, or scarring. * Previous ocular surgery or significant ocular trauma. * Current contact lens use or recent contact lens use without adequate discontinuation period. * Active ocular surface disease or severe dry eye. * Glaucoma, uveitis, retinal disease, or other significant ocular pathology. * Diabetes mellitus, autoimmune disease, thyroid disease, pregnancy, or lactation. * Use of other hormonal therapy or systemic medications known to affect corneal parameters.
| Facility | City | Country | Status |
|---|---|---|---|
| Ophthalmology Department, Sohag University Hospital, Faculty of Medicine, Sohag University | Sohag, Sohag Governorate | Egypt |