28 terminated. 28 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 28 | Terminated 28 |
Follow Congenital Abnormalities: new trials by email Literature Review of Congenital Abnormalities trials Research Report on Congenital Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Use of Liquid Stable Levothyroxine in Trisomy 21 Pediatric Patients Liquid stable levothyroxine (L-T4) Tirosint-SOL, Oral tablet levothyroxine (L-T4) - Hypothyroidism, Trisomy 21 | Phase 4 | Terminated | Children's Mercy Hospital Kansas City | 6 | 2021-01-18 | 2023-09-13 |
| Paravertebral Nerve Blocks in Neonates Paravertebral Nerve Block, Standard of Care Anesthesia - Congenital Heart Disease | Phase 4 | Terminated | Emory University | 16 | 2018-07-18 | 2025-03-24 |
| A Study of Crisaborole Ointment 2%; Crisaborole Vehicle; TCS and TCI in Subjects Aged ≥ 2 Years, With Mild-moderate AD Crisaborole ointment, 2%, Hydrocortisone butyrate cream, 0.1%, Pimecrolimus cream, 1% - Atopic Dermatitis | Phase 4 | Terminated | Pfizer | 237 | 2018-04-27 | 2022-01-10 |
| Evaluation of Glycerin Suppositories to Improve Bowel Function in Gastroschisis Glycerin Suppository - Gastroschisis | Phase 4 | Terminated | Indiana University | 16 | 2017-10-01 | 2021-10-12 |
| The Effects of Eplerenone on Markers of Myocardial Fibrosis in Adult Congenital Heart Disease Eplerenone - Tetralogy of Fallot, Transposition of the Great Vessels With an Arterial Switch | Phase 4 | Terminated | Washington University School of Medicine | 26 | 2013-08-01 | 2018-05-04 |
| A Comparison Trial Between PCA and Epidural Analgesia for Pectus Excavatum Repair Hydromorphone, Morphine - Pectus Excavatum | Phase 4 | Terminated | Baylor College of Medicine | 62 | 2012-08-01 | 2020-06-11 |
| Multi-centre Study to Assess the Long-term Performance of the Deltamotion Cup System in Primary Hip Replacement Surgery Delta Motion - Rheumatoid Arthritis, Osteoarthritis | Phase 4 | Terminated | DePuy International | 250 | 2012-07-01 | 2018-07-19 |
| A Observational Study to Evaluate Apligraf(R) in Nonhealing Wounds of Subjects With Epidermolysis Bullosa Apligraf - Epidermolysis Bullosa, Wound Healing | Phase 4 | Terminated | University Hospital, Basel, Switzerland | 3 | 2012-06-01 | 2015-03-10 |
| Liraglutide Use in Prader-Willi Syndrome Liraglutide - Diabetes Mellitus Type 2, Prader Willi Syndrome | Phase 4 | Terminated | Vancouver General Hospital | 1 | 2012-02-01 | 2015-12-09 |
| Sabril for Complex Partial Seizures in Adult Tolerability Study (TS) Patients vigabatrin - Complex Partial Seizures | Phase 4 | Terminated | University of Pennsylvania | 1 | 2010-08-01 | 2017-07-12 |
| An Electronic Data Capture Study to Assess the Long-term Performance of the DePuy PROXIMA™ Hip in Primary Total Hip Replacement DePuy Proxima™ Hip - Rheumatoid Arthritis, Osteoarthritis | Phase 4 | Terminated | DePuy International | 42 | 2010-02-01 | 2017-06-26 |
| Safety/Efficacy Study of Optimizing Ibuprofen Dosing to Achieve Higher PDA Closure Rates optimized ibuprofen, Standard Ibuprofen - Patent Ductus Arteriosus | Phase 4 | Terminated | OSF Healthcare System | 10 | 2009-08-01 | 2014-01-28 |
| Trilogy AB Acetabular Hip System Post Approval Study Trilogy AB Acetabular Hip Implant System - Osteoarthritis, Avascular Necrosis | Phase 4 | Terminated | Zimmer Biomet | 31 | 2009-04-01 | 2014-11-26 |
| Statins and Endothelial Function in Patients With Coarctation of the Aorta atorvastatin, Sugar pill - Coarctation of the Aorta | Phase 4 | Terminated | University of California, San Francisco | 12 | 2008-08-01 | 2013-10-14 |
| Tranexamic Acid for Craniofacial Surgery Tranexamic acid, saline - Craniosynostosis, Bleeding | Phase 4 | Terminated | University of Pittsburgh | 20 | 2008-07-01 | 2017-02-15 |
| A Single Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Ceramic-on-ceramic Bearing in Primary Total Hip Replacement Pinnacle™ Acetabular System - Rheumatoid Arthritis, Osteoarthritis | Phase 4 | Terminated | DePuy International | 98 | 2007-01-01 | 2016-10-07 |
| Metal on Metal Versus Metal on Highly Crossed Linked Polyethylene Sytem Metal on Metal Hip System, Highly Cross Linked Polyethylene cup System - Osteoarthritis, Avascular Necrosis | Phase 4 | Terminated | Nova Scotia Health Authority | 41 | 2007-01-01 | 2015-05-15 |
| Multi-Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Resurfacing and Primary Total Hip Replacement DePuy ASR™ Hip System, DePuy ASR™ XL Head / ASR™ Acetabular Cup System - Rheumatoid Arthritis, Osteoarthritis | Phase 4 | Terminated | DePuy International | 329 | 2006-09-01 | 2016-08-04 |
| A Randomised Study to Compare Metal Ion Release and Long-term Performance of the Pinnacle™ Cup With a Ceramic-on-Metal or a Metal-on-Metal Bearing Pinnacle™ Acetabular System - Osteoarthritis, Post-traumatic Arthritis | Phase 4 | Terminated | DePuy International | 5 | 2006-07-01 | 2016-05-11 |
| A Two Centre Study to Assess the Stability and Long-term Performance of the C-Stem™ AMT in a Total Primary Hip Replacement C-Stem™ AMT Femoral Component (standard and high off-set variants) - Rheumatoid Arthritis, Osteoarthritis | Phase 4 | Terminated | DePuy International | 5 | 2006-07-01 | 2017-06-26 |
Showing 20 of 28. Sign in to see all of them.
Hip Dislocation, Congenital (14) · Osteoarthritis (14) · Osteonecrosis (14) · Arthritis, Rheumatoid (11) · Collagen Diseases (8) · Slipped Capital Femoral Epiphyses (8) · Ductus Arteriosus, Patent (2) · Premature Birth (2) · Aortic Coarctation (1) · Arthritis (1) · Craniosynostoses (1) · Dermatitis, Atopic (1) · Diabetes Mellitus, Type 2 (1) · Down Syndrome (1) · Epidermolysis Bullosa (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (28) · Musculoskeletal Abnormalities (18) · Musculoskeletal Diseases (18) · Bone Diseases (17) · Pathological Conditions, Signs and Symptoms (17) · Pathologic Processes (15) · Skin and Connective Tissue Diseases (15) · Developmental Dysplasia of the Hip (14) · Necrosis (14) · Rheumatic Diseases (14) · Arthritis (13) · Joint Diseases (13) · Connective Tissue Diseases (12) · Immune System Diseases (12)
Arthroplasty (1) · Arthroplasty, Replacement, Hip (1) · Atorvastatin (1) · Azithromycin (1) · Bupivacaine (1) · Epinephrine (1) · Eplerenone (1) · Fentanyl (1) · Hydromorphone (1) · Ibuprofen (1) · Ketamine (1) · Liraglutide (1) · Morphine (1) · Propofol (1) · Rocuronium (1)
DePuy International (11) · Alan Fujii (1) · Baylor College of Medicine (1) · CPL Associates (1) · Children's Mercy Hospital Kansas City (1) · DePuy Orthopaedics (1) · Emory University (1) · Indiana University (1) · Nova Scotia Health Authority (1) · OSF Healthcare System (1) · Pfizer (1) · University Hospital, Basel, Switzerland (1) · University of California, San Francisco (1) · University of Pennsylvania (1) · University of Pittsburgh (1)
United States (14) · United Kingdom (8) · Germany (5) · Italy (4) · Switzerland (3) · Czechia (2) · Portugal (2) · Spain (2) · Australia (1) · Austria (1) · Canada (1) · China (1) · Finland (1) · France (1) · Hong Kong (1)
Alan Ladd, M.D. (1) · Alan M Fujii, MD (1) · Andreas Arnold, MD (1) · Chris Glover, MD (1) · Dave Whalen, BS, DC (1) · Gwo-Chin Lee, MD (1) · James R Hocker, MD (1) · Jason Kong, MD, FRCPC (1) · Jerome J Schentag, Pharm.D. (1) · John Pollard, MD (1) · Joseph Paladino, Pharm.D. (1) · Justin B Long, MD (1) · Kevin Schrock, MD (1) · Ross K Leighton, MD (1)
PMID 19956811, PMID 20336076, PMID 20336077
2018 (1)