222 completed, 73 unknown, 64 recruiting, 41 terminated. 115 Not applicable, 109 Phase 2, 61 Phase 1, 45 Phase 3, 43 Phase 4.
Follow Collagen Diseases: new trials by email Literature Review of Collagen Diseases trials Research Report on Collagen Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Exercise and Lifestyle Programme for Adults With Vascular Ehlers-Danlos Syndrome: A Feasibility Study Co-designed exercise-based lifestyle intervention - Vascular Ehlers Danlos Syndrome | Not applicable | Not yet recruiting | Sheffield Hallam University | 40 | 2027-03-01 | 2026-07-13 |
| Regenerative Medicine for Joint Hypermobility and Instability Dextrose 20% Prolotherapy, Autologous Platelet-Rich Plasma, Doxycycline Hyclate Injectable (Investigational) - Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS) | Phase 1 / Phase 2 | Not yet recruiting | Manhattan Pain Medicine, PLLC | 100 | 2027-01-15 | 2026-10-06 |
| Mesenchymal Cell Therapy in Osteogenesis Imperfecta (OI) Bone marrow-derived mesenchymal stromal cells (MSCs) - Osteogenesis Imperfecta, Osteogenesis Imperfecta Type III | Phase 1 / Phase 2 | Not yet recruiting | Emory University | 12 | 2027-01-01 | 2026-05-08 |
| Phase 4 Master Protocol for Patients Prescribed Prademagene Zamikeracel for the Treatment of Wounds Non-conforming pz-cel surgical application to RDEB wounds, Additional biopsies, Pz-cel surgical application to DEB wounds - Epidermolysis Bullosa (EB), Recessive Dystrophic Epidermolysis Bullosa (RDEB) | Phase 4 | Not yet recruiting | Abeona Therapeutics, Inc | 100 | 2026-11-01 | 2026-08-06 |
| A Study to Evaluate ENERGI-F703EB Cream in Epidermolysis Bullosa ENERGI-F703EB Cream, Matched vehicle cream - Epidermolysis Bullosa (EB), Junctional Epidermolysis Bullosa | Phase 2 | Recruiting | Energenesis Biomedical Co., Ltd. | 24 | 2026-10-08 | 2026-10-05 |
| The Ultrasound-Guided Dextrose Prolotherapy in Ehlers-Danlos Syndrome Patients Dextrose 50% Intravenous Solution, Lidocaine 1% Injectable Solution - Ehlers-Danlos Syndrome, Low Back Pain | Phase 3 | Withdrawn | Tulane University | 2026-10-05 | 2026-10-08 | |
| COG+OT Telerehabilitation for Adults With Subjective Cognitive Complaints COG+OT Telerehabilitation - Subjective Cognitive Complaints, Ehlers-Danlos Syndrome | Not applicable | Not yet recruiting | Medical University of South Carolina | 16 | 2026-10-01 | 2026-09-21 |
| Morphology in Oral Rare Syndromes & Artificial Intelligence for Clinical Diagnosis intra-oral 3D optical impression - Osteogenesis Imperfecta, Rare Bone Disorders | Not applicable | Not yet recruiting | University Hospital, Bordeaux | 240 | 2026-09-01 | 2026-06-24 |
| Polidocanol 1% and Steroid in Keloids and Hypertrophic Scars Group 1 (polidocanol 1% group):, Group 2 (Triamcinolone acetonide group):, Group 3 (combined Triamcinolone acetonide and polidocanol 1% group): - Keloid and Hypertrophic Scars | Not applicable | Not yet recruiting | Sohag University | 90 | 2026-08-01 | 2026-05-26 |
| A Clinical Study on the Safety and Efficacy of Wide-Band Ultrasound Combined With Traditional Chinese Medicine Preparations in the Prevention and Treatment of Keloids Wide-Band Ultrasound, traditional Chinese medicine - Keloid | Phase 1 / Phase 2 | Not yet recruiting | Fujian Medical University Union Hospital | 120 | 2026-08-01 | 2026-07-01 |
| A Dose REgimen-Finding Study of AGA2115 in Chinese Patients With Osteogenesis ImpeRfecta (EIR) AGA2115 - Osteogenesis Imperfecta (OI) | Phase 2 | Recruiting | Angitia Biopharmaceuticals Guangzhou Limited | 48 | 2026-07-14 | 2026-09-22 |
| STABLE Pilates for Hypermobility Pilates, Education - Ehlers-Danlos Syndrome (EDS), Hypermobile EDS (hEDS) | Not applicable | Recruiting | Brigham and Women's Hospital | 100 | 2026-07-09 | 2026-08-19 |
| Intralesional Cryosurgery Alone Versus Combined With 5-FU and Triamcinolone for Keloids Intralesional Cryotherapy + Saline Injection, Intralesional Cryotherapy + TAC/5-FU Injection - Keloid | Not applicable | Not yet recruiting | Assiut University | 32 | 2026-07-01 | 2026-04-13 |
| Targeting Collagen VII Antibodies in Bullous Diseases Using Efgartigimod IV (VYVGART) Efgartigimod - Epidermolysis Bullosa (EB), Epidermolysis Bullosa Acquisita | Phase 1 / Phase 2 | Not yet recruiting | M. Peter Marinkovich | 18 | 2026-07-01 | 2026-05-05 |
| Treatment of Dysphagia in Patients With Dystrophic Epidermolysis Bullosa With Budesonide: a Retrospective Bicentric Study Nice - Paris St Louis / Necker (EBUDE Study) The retrospective data collected will be entered into an eCRF and then analyzed centrally - Recessive Dystrophic Epidermolysis Bullosa, Dysphagia | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de Nice | 15 | 2026-07-01 | 2026-07-06 |
| Scar Gel Product Family Clinical Investigation Dermatix, Dermatix Ultra - Hypertrophic Scars, Keloids | Not yet recruiting | Hanson Medical, Inc. | 150 | 2026-07-01 | 2026-07-06 | |
| EXACT Study: A Blinded Study in Patients With Alport Syndrome to Evaluate Exaluren Efficacy and Safety Exaluren - Alport Syndrome, X-Linked, Alport Syndrome, Autosomal Recessive | Phase 2 | Recruiting | Eloxx Pharmaceuticals, Inc. | 24 | 2026-06-30 | 2026-09-30 |
| Topical Cryotherapy and Keloid/Hypertrophic Scars Cryotherapy with liquid nitrogen, Intralesional Triamcinolone 10 mg/ml - Keloid Scars, Hypertrophic Scars | Phase 3 | Recruiting | Sonal Choudhary | 30 | 2026-06-10 | 2026-06-12 |
| GRACE II (General Retrospective Analysis of Commercial Experience With AGN1 LOEP) AGN1 LOEP - Osteoporosis | Not yet recruiting | AgNovos Healthcare, LLC | 305 | 2026-06-01 | 2026-05-19 | |
| siRNA Microneedle Patches for Ear Keloid Post-Surgical Scars Small interfering RNA (siRNA) Microneedle Patches, Carbon Dioxide (CO2) Laser Surgery, Intralesional Triamcinolone 40 mg/mL - Keloid of Ear Lobe | Phase 2 | Not yet recruiting | Ong Kim Yao | 158 | 2026-06-01 | 2026-07-06 |
Showing 20 of 482. Sign in to see all of them.
Keloid (134) · Osteogenesis Imperfecta (84) · Epidermolysis Bullosa Dystrophica (77) · Ehlers-Danlos Syndrome (64) · Cicatrix, Hypertrophic (40) · Nephritis, Hereditary (37) · Cicatrix (36) · Epidermolysis Bullosa (27) · Ehlers-Danlos Syndrome, Type IV (16) · Osteoarthritis (15) · Marfan Syndrome (14) · Hip Dislocation, Congenital (13) · Osteonecrosis (13) · Slipped Capital Femoral Epiphyses (13)
Skin and Connective Tissue Diseases (481) · Connective Tissue Diseases (474) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (291) · Genetic Diseases, Inborn (241) · Pathological Conditions, Signs and Symptoms (212) · Congenital Abnormalities (202) · Pathologic Processes (185) · Skin Diseases (184) · Skin Diseases, Genetic (154) · Skin Abnormalities (151) · Musculoskeletal Diseases (138) · Fibrosis (132) · Bone Diseases (116) · Bone Diseases, Developmental (113)
Triamcinolone Acetonide (15) · Sodium Chloride (8) · setrusumab (7) · Lidocaine (6) · Triamcinolone (6) · Zoledronic Acid (6) · Saline Solution (5) · Adrenal Cortex Hormones (4) · Blood Specimen Collection (4) · Botulinum Toxins, Type A (4) · Diphosphonates (4) · Fluorouracil (4) · Vitamin D (4) · Bone Marrow Transplantation (3) · Busulfan (3)
DePuy International (13) · Assistance Publique - Hôpitaux de Paris (8) · Tirgan, Michael H., M.D. (8) · Baylor College of Medicine (7) · Krystal Biotech, Inc. (7) · Ultragenyx Pharmaceutical Inc (7) · Assiut University (6) · Istituto Ortopedico Rizzoli (6) · Stanford University (6) · Abeona Therapeutics, Inc (5) · Amgen (5) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (5) · Novartis Pharmaceuticals (5) · University Health Network, Toronto (5) · Cairo University (4)
United States (217) · France (63) · United Kingdom (42) · Italy (32) · Canada (30) · Germany (29) · Spain (23) · China (17) · Australia (16) · Egypt (13) · Poland (12) · Belgium (11) · Netherlands (11) · Czechia (10) · Austria (9)
Michael H Tirgan, MD (7) · Clifford E Kashtan, MD (3) · Frank Rauch, M.D. (3) · Joshua J Zimmerberg, M.D. (3) · Alfred T Lane (2) · Damien Bates, MD, PhD, FRACS (Plast.) (2) · David Woodley, MD (2) · Diana L Driscoll, O.D. (2) · Hal Landy, MD (2) · Iltefat H Hamzavi, MD (2) · Jared Jagdeo, MD, MS (2) · Jean Tang, MD, PhD (2)
PMID 40938675, PMID 33159213, PMID 42470570, PMID 20825986, PMID 20927486, PMID 38724717, PMID 10744172, PMID 10808705, PMID 10831929, PMID 10927682, PMID 11013547, PMID 11415789, PMID 11742607, PMID 11807470, PMID 11887386, PMID 12028527, PMID 12028528, PMID 12032371, PMID 12711943, PMID 14710509, PMID 15113289, PMID 15140214, PMID 15209788, PMID 15253184, PMID 15365369, PMID 15615575, PMID 16010345, PMID 16079683, PMID 16163087, PMID 16254707, PMID 16267427, PMID 16299708, PMID 16413399, PMID 16437463, PMID 16575391, PMID 16639985, PMID 16696385, PMID 16736200, PMID 16875470, PMID 17214728, PMID 17261663, PMID 17478730, PMID 17644502, PMID 17909106, PMID 17909210, PMID 18042333, PMID 18086474, PMID 18459515, PMID 18547784, PMID 18804556
2016 (4), 2023 (4), 2015 (2), 2017 (2), 2018 (2), U01TR001263 (2), 1OT2OD028183-01 (1), 2009 (1), 2014 (1), 2019 (1), 268201000048C-5-0-1 (1), N01HV681997 (1), R01AR055914 (1), R01DK141114 (1), R01MD019235 (1)