23 completed, 12 unknown, 6 terminated, 4 withdrawn. 52 Phase 2, 10 Phase 1, 10 Phase 3.
Follow Cerebral Infarction: new trials by email Literature Review of Cerebral Infarction trials Research Report on Cerebral Infarction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Human Umbilical Cord Mesenchymal Stem Cell Therapy (19#iSCLife®-CI) for Cerebral Infarction Patients in Convalescent Period. Allogeneic umbilical cord mesenchymal stem cell, Aspirin Enteric-coated Tablets & Atorvastatin Calcium - Cerebral Infarction | Phase 1 / Phase 2 | Suspended | Sclnow Biotechnology Co., Ltd. | 40 | 2026-12-31 | 2026-04-23 |
| Safety and Efficacy of Edaravone Dexborneol Sublingual Tablets for Blood-Brain Barrier Dysfunction in CADASIL Edaravone Dexborneol Sublingual Tablets - CADASIL | Phase 2 | Not yet recruiting | Huashan Hospital | 60 | 2026-07-01 | 2026-07-09 |
| Safety and Efficacy of Baricitinib After Endovascular Treatment in Acute Anterior Circulation Large Vessel Occlusion: A Multicenter, Randomized Controlled Clinical Trial 2mg Baricitinib, 4mg Baricitinib, Placebo - Acute Ichemic Stroke, Anterior Cerebral Artery Stroke | Phase 2 / Phase 3 | Not yet recruiting | The First Affiliated Hospital of University of Science and Technology of China | 750 | 2026-03-17 | 2026-03-04 |
| Effect of Xenon on Brain Injury After Aneurysmal Subarachnoid Hemorrhage Xenon, air/oxygen - Subarachnoid Hemorrhage, Aneurysmal, Cerebral Injury | Phase 2 | Recruiting | Turku University Hospital | 160 | 2025-04-22 | 2025-05-01 |
| A Dose-Response Controlled Trial of Bevifibatide for Acute Ischemic Stroke Bevifibatide citrate injection - Ischemic Stroke, Acute, Ischemic Stroke | Phase 2 | Recruiting | Zhujiang Hospital | 40 | 2025-02-10 | 2025-07-17 |
| Tirofiban for the Prevention of Early Neurological Deterioration After Intravenous Thrombolysis in Acute Ischemic Stroke Tirofiban Hydrochloride, Standard medical treatment (SMT) - Acute Stroke, Ischemic Stroke, Acute | Phase 2 / Phase 3 | Unknown | Capital Medical University | 302 | 2024-11-20 | 2024-10-29 |
| CERebrolysin In CADASIL Cerebrolysin, 0.9 % NaCl - Cadasil | Phase 2 | Active not recruiting | Ever Neuro Pharma GmbH | 30 | 2023-11-29 | 2025-02-25 |
| Adrenomedullin for CADASIL Adrenomedullin - Cadasil | Phase 2 | Completed | National Cerebral and Cardiovascular Center, Japan | 60 | 2022-01-06 | 2023-10-10 |
| Safety and Efficacy of Fremanezumab for Migraine in Adult CADASIL Fremanezumab, Placebo - Cadasil, Migraine | Phase 2 | Withdrawn | Mayo Clinic | 2021-12-01 | 2022-02-28 | |
| Retina is a Marker for Cerebrovascular Heath Cilostazol - Cerebral Small Vessel Diseases, Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy | Phase 1 / Phase 2 | Recruiting | Mayo Clinic | 100 | 2021-02-09 | 2026-08-03 |
| Efficacy and Safety of Tocotrienols in CADASIL HOV-12020 (Palm tocotrienols complex), Placebo - Cadasil | Phase 2 | Completed | Hovid Berhad | 50 | 2020-12-21 | 2026-02-02 |
| Efficacy and Safety of Ferrous Iron on the Prevention of Vascular Cognitive Impairment Among Patients With Cerebral Infarction/TIA (FAVORITE) Ferrous succinate - Vascular Cognitive Impairment, Dementia, Vascular | Phase 2 | Unknown | Beijing Tiantan Hospital | 1006 | 2019-04-01 | 2020-07-13 |
| Effect of Mesenchymal Stem Cells(MSCs) Transplantation for Acute Cerebral Infarction Patients human umbilical cord mesenchymal stem cells, Placebo, standardized treatment - Infarction, Middle Cerebral Artery, Infarction, Anterior Cerebral Artery | Phase 1 / Phase 2 | Unknown | Shanghai East Hospital | 120 | 2019-01-13 | 2023-04-18 |
| Fluoxetine Opens Window to Improve Motor Recovery After Stroke Fluoxetine Hydrochloride, Placebo, Exercise Program - Stroke, Cerebrovascular Accident | Phase 2 | Completed | University Health Network, Toronto | 52 | 2019-01-01 | 2022-11-04 |
| Investigation of Neural Stem Cells in Ischemic Stroke CTX0E03 Drug Product and delivery device, Placebo - Ischemic Stroke, Chronic Stroke | Phase 2 | Terminated | ReNeuron Limited | 15 | 2018-08-31 | 2021-08-13 |
| Determining the Optimal Dose of Tenecteplase Before Endovascular Therapy for Ischaemic Stroke (EXTEND-IA TNK Part 2) Tenecteplase - Ischemic Stroke | Phase 2 | Completed | Neuroscience Trials Australia | 300 | 2017-12-06 | 2020-03-04 |
| Efficacy and Safety Study of Neu2000KWL for Acute Ischemic Stroke Patients Within 6 Hours of Onset Neu2000KWL, Placebos - Stroke, Cerebral Infarction | Phase 2 | Completed | Beijing Tiantan Hospital | 236 | 2017-03-02 | 2020-07-24 |
| A Study to Evaluate the Safety and Efficacy of Basmisanil in Adults With Severe Motor Impairment Following an Ischemic Stroke Basmisanil, Placebo - Stroke | Phase 2 | Terminated | Hoffmann-La Roche | 5 | 2017-02-20 | 2019-01-02 |
| Stroke Treatment Associate to Rehabilitation Therapy and Transcranial DC Stimulation Transcranial direct current stimulation, Constraint-Induced Movement Therapy, Placebo - Stroke, Cerebrovascular Disorders | Phase 2 / Phase 3 | Unknown | Federal University of Paraíba | 40 | 2016-02-01 | 2015-12-07 |
| REperfusion With Cooling in CerebraL Acute IscheMia II Normothermia, Mild hypothermia, Trevo Pro Retriever (Stryker Corp.) - Ischemic Stroke, Hypothermia | Phase 2 | Withdrawn | WellStar Health System | 2016-02-01 | 2016-02-17 |
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Stroke (28) · Ischemic Stroke (13) · Infarction, Middle Cerebral Artery (12) · Cerebrovascular Disorders (9) · Brain Diseases (7) · CADASIL (7) · Brain Ischemia (6) · Central Nervous System Diseases (6) · Brain Infarction (5) · Vascular Diseases (5) · Cardiovascular Diseases (4) · Ischemia (4) · Nervous System Diseases (4) · Hypothermia (3)
Infarction (52) · Necrosis (52) · Pathological Conditions, Signs and Symptoms (52) · Pathologic Processes (50) · Cardiovascular Diseases (48) · Ischemia (48) · Nervous System Diseases (48) · Brain Infarction (47) · Vascular Diseases (47) · Brain Ischemia (46) · Central Nervous System Diseases (46) · Brain Diseases (45) · Cerebrovascular Disorders (43) · Stroke (24) · Intracranial Arterial Diseases (21)
Transcranial Direct Current Stimulation (4) · Tenecteplase (3) · Aspirin (2) · Constraint Induced Movement Therapy (2) · Saline Solution (2) · Acupuncture Therapy (1) · Adrenomedullin (1) · Amantadine (1) · Atorvastatin (1) · Cilostazol (1) · Cool-Down Exercise (1) · Coronary Artery Bypass (1) · Dabigatran (1) · Deferoxamine (1) · Fluoxetine (1)
Federal University of Paraíba (3) · Beijing Tiantan Hospital (2) · Mayo Clinic (2) · Merck Sharp & Dohme LLC (2) · ReNeuron Limited (2) · All India Institute of Medical Sciences (1) · Bispebjerg Hospital (1) · CHABiotech CO., Ltd (1) · Capital Medical University (1) · Celularity Incorporated (1) · Centre Hospitalier Universitaire de Nice (1) · Children's Hospital of Fudan University (1) · China Medical University Hospital (1) · Ever Neuro Pharma GmbH (1) · Germans Trias i Pujol Hospital (1)
China (13) · United States (6) · France (4) · Spain (4) · Brazil (3) · Germany (3) · United Kingdom (3) · Canada (2) · South Korea (2) · Australia (1) · Austria (1) · Czechia (1) · Denmark (1) · Finland (1) · India (1)
Bradley MacIntosh, PhD (1) · Chuanzhi Duan, MD (1) · Courtney Pollock, PhD (1) · David Ho (1) · Francesco Orzi, MD (1) · Gang Li, Doctor (1) · Gang Zhao, M.D. (1) · James C. Grotta, MD (1) · James F Meschia (1) · Jia Qian, doctor (1) · Kameshwar Prasad, MBBS, MD (1) · Keith W Muir (1)
PMID 22163120, PMID 16282547, PMID 16336965, PMID 18468545, PMID 19570514, PMID 19834012, PMID 20947374, PMID 20966420, PMID 21852153, PMID 22764211, PMID 23197640, PMID 23370205, PMID 24610327, PMID 25107583, PMID 25304723, PMID 25378424, PMID 25530442, PMID 25671797, PMID 25938519, PMID 26387127, PMID 26420269, PMID 26752061, PMID 26822418, PMID 26978207, PMID 27834742, PMID 29169472, PMID 30156755, PMID 31564231, PMID 31570084, PMID 32078683, PMID 33175411, PMID 33236783, PMID 33408145, PMID 34439518, PMID 34906976, PMID 35017305, PMID 35130557, PMID 36289001, PMID 36878701, PMID 37256974, PMID 37337295, PMID 38419030, PMID 38502892, PMID 38648030, PMID 38768068, PMID 38789134, PMID 41541089, PMID 42005919
2015 (1), 2019 (1), P50NS044148 (1), P50NS044227 (1)