7 completed, 3 terminated, 3 unknown, 1 not yet recruiting. 14 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 14 | Completed 7, Terminated 3, Unknown 3, Not yet recruiting 1 |
| Phase 2 | 4 | Completed 1, Not yet recruiting 1, Terminated 1, Unknown 1 |
Follow Central Nervous System Parasitic Infections: new trials by email Literature Review of Central Nervous System Parasitic Infections trials Research Report on Central Nervous System Parasitic Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oxfendazole in Mild Parenchymal Brain Cysticercosis Oxfendazole single dose, Oxfendazole three doses, albendazole plus praziquantel regime - Brain Cysticercosis | Phase 2 / Phase 3 | Not yet recruiting | Universidad Peruana Cayetano Heredia | 544 | 2026-12-01 | 2026-05-01 |
| Treating Brain Swelling in Pediatric Cerebral Malaria Mechanical ventilation, Hypertonic saline - Malaria, Cerebral | Phase 3 | Completed | Michigan State University | 57 | 2018-01-08 | 2025-03-17 |
| Sub Arachnoid Neurocysticercosis Treatment Outcome (SANTO) Albendazole and praziquantel, Albendazole and praziquantel placebo - Neurocysticercosis | Phase 3 | Terminated | Universidad Peruana Cayetano Heredia | 107 | 2016-11-14 | 2022-11-16 |
| Treatment of Peri-calcification Edema in Neurocysticercosis (NCC) Acetazolamide, Dexamethasone - Neurocysticercosis | Phase 2 / Phase 3 | Terminated | Universidad Peruana Cayetano Heredia | 4 | 2015-12-04 | 2025-04-01 |
| Effects of 2 Different Duration of Albendazole Therapy in Patients With Neurocysticercosis in Brain ≤ 5 Lesions on CT 7 days of albendazole 15 mg/kg/day, 28 days of albendazole 15 mg/kg/day - Neurocysticercosis | Phase 3 | Completed | All India Institute of Medical Sciences | 97 | 2014-03-01 | 2016-01-01 |
| Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC Immunochromatographic HAT tests (DSD), Card Agglutination Trypanosoma Test, TB POC Nucleic Acid Amplification Test (Molbio Diagnostics) - Neurological Disorders, Cerebral Malaria | Phase 3 | Completed | Institute of Tropical Medicine, Belgium | 352 | 2012-09-01 | 2016-01-18 |
| Prevention of Congenital Toxoplasmosis With Pyrimethamine + Sulfadiazine Versus Spiramycine During Pregnancy Pyrimethamine/Sulfadiazine, Spiramycine - Congenital Toxoplasmosis | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 149 | 2010-11-01 | 2016-09-29 |
| Assessment of Two Therapeutic Strategies in the Treatment of Children With Congenital Toxoplasmosis reducing treatment to 3 months, registered length of treatment - Congenital Toxoplasmosis | Phase 3 | Terminated | Centre Hospitalier Universitaire Dijon | 302 | 2010-07-28 | 2024-02-22 |
| Neurocysticercosis: Combined Treatment With Praziquantel (PZQ) and Albendazole (ABZ) Praziquantel, Albendazole, ABZ Placebo - Neurocysticercosis, Epilepsy | Phase 2 / Phase 3 | Completed | Universidad Peruana Cayetano Heredia | 156 | 2010-01-01 | 2015-06-11 |
| Randomized Trial of Erythropoietin During Cerebral Malaria Placebo, Erythropoietin - Cerebral Malaria | Phase 2 / Phase 3 | Unknown | Claude Bernard University | 120 | 2007-10-01 | 2008-06-13 |
| Corticosteroids to Reduce Frequency of Seizures in Neurocysticercosis Patients Albendazole, Dexamethasone, Omeprazole - Neurocysticercosis | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 110 | 2006-04-01 | 2017-02-03 |
| Mannitol as Adjunct Therapy for Childhood Cerebral Malaria Mannitol - Cerebral Malaria | Phase 3 | Unknown | Makerere University | 156 | 2004-10-01 | 2005-06-24 |
| Efficacy of Intrarectal Versus Intravenous Quinine for the Treatment of Childhood Cerebral Malaria Intrarectal quinine - Cerebral Malaria | Phase 3 | Unknown | Makerere University | 108 | 2003-09-01 | 2005-08-04 |
| A Pilot Study of Neurocysticercosis Treatment albendazole, placebo - Neurocysticercosis | Phase 3 | Completed | Columbia University | 178 | 2001-02-01 | 2010-02-08 |
Neurocysticercosis (7) · Malaria, Cerebral (5) · Malaria (3) · Toxoplasmosis, Congenital (2) · Cestode Infections (1) · Coma (1) · Cysticercosis (1) · Epilepsy (1) · Meningitis, Bacterial (1) · Meningitis, Cryptococcal (1) · Neglected Diseases (1) · Nervous System Diseases (1) · Neurosyphilis (1) · Seizures (1) · Taeniasis (1)
Central Nervous System Diseases (14) · Central Nervous System Infections (14) · Infections (14) · Parasitic Diseases (14) · Nervous System Diseases (13) · Central Nervous System Helminthiasis (7) · Central Nervous System Protozoal Infections (7) · Helminthiasis (7) · Protozoan Infections (7) · Cestode Infections (6) · Cysticercosis (6) · Taeniasis (6) · Mosquito-Borne Diseases (5) · Vector Borne Diseases (5)
Albendazole (6) · Dexamethasone (2) · Praziquantel (2) · Acetazolamide (1) · Erythropoietin (1) · Mannitol (1) · Omeprazole (1) · Pyrimethamine (1) · Respiration, Artificial (1) · Saline Solution, Hypertonic (1) · Spiramycin (1) · Sulfadiazine (1) · epoetin beta (1) · oxfendazole (1)
Universidad Peruana Cayetano Heredia (4) · Makerere University (2) · All India Institute of Medical Sciences (1) · Assistance Publique - Hôpitaux de Paris (1) · Centre Hospitalier Universitaire Dijon (1) · Claude Bernard University (1) · Columbia University (1) · Institute of Tropical Medicine, Belgium (1) · Michigan State University (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1)
Peru (4) · France (2) · Uganda (2) · Democratic Republic of the Congo (1) · Ecuador (1) · India (1) · Malawi (1) · Mali (1)
Hector H. Garcia, MD, PhD (2) · E. Javier Pretell, MD (1) · Emmanuel Bottieau, MD (1) · Hector H Garcia, MD, PhD (1) · Hector H. Garcia Lescano, Ph.D (1) · Hector H. Garcia, MD (1) · Jane Achan, MBChB (1) · Javier A. Bustos, MD (1) · Laurent Mandelbrot, MD (1) · Marleen Boelaert, MD, PhD (1) · Sheffali Gulati, MD (1) · Terrie E Taylor, DO (1) · Theodore E. Nash, MD (1)
PMID 17958887, PMID 18495737, PMID 19630971, PMID 19852829, PMID 21332573, PMID 24999157, PMID 26984901, PMID 34020114
2009 (1), R01NS054805 (1), U01AI126610 (1)