1345 completed, 187 unknown, 89 recruiting, 89 terminated. 376 Phase 1, 355 Not applicable, 354 Phase 2, 294 Phase 3, 233 Phase 4.
Follow Protozoan Infections: new trials by email Literature Review of Protozoan Infections trials Research Report on Protozoan Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| OPTIMAL LEAP: Optimizing Dihydroartemisinin-Piperaquine IPTsc Intervals to Advance Learning, Executive Function, Attendance, and Antimalarial Resistance Surveillance in Kenyan Schoolchildren Monthly DP, Quarterly DP - Malaria, Asymptomatic Malaria | Phase 3 | Not yet recruiting | Indiana University | 1500 | 2028-01-01 | 2026-09-01 |
| Permethrin-Treated Baby Wraps for Malaria Prevention in Refugee Settings Factory-treated lesu, Soaked lesu, Untreated lesu - Malaria (Plasmodium Falciparum), Malaria Incidence | Not applicable | Not yet recruiting | University of North Carolina, Chapel Hill | 1350 | 2027-09-01 | 2026-10-29 |
| Study to Assess Safety and Clinical Responses With Coartem® Baby Dispersible Tablets in Paediatric Patients Weighing 2 to <5 kg With Uncomplicated Malaria Coartem® Baby - Malaria | Phase 4 | Not yet recruiting | Novartis Pharmaceuticals | 20 | 2027-06-18 | 2026-07-20 |
| Challenge Trial of PfSPZ-LARC2 Vaccine in Burkina Faso PfSPZ-LARC2 Vaccine, PfSPZ Challenge, Normal Saline - Malaria (Plasmodium Falciparum) | Phase 1 | Not yet recruiting | Sanaria Inc. | 45 | 2027-03-01 | 2026-07-31 |
| Spatial Emanator Deployment Strategies for Malaria Control in Papua New Guinea Spatial emanator outdoor, Spatial emanator indoor - Malaria | Not applicable | Not yet recruiting | Macfarlane Burnet Institute for Medical Research and Public Health Ltd | 4350 | 2027-02-01 | 2026-11-10 |
| Insecticide-Treated Baby Wraps for the Prevention of Malaria Permethrin-treated lesu, Etofenprox-treated lesu, Untreated lesu - Malaria (Plasmodium Falciparum), Malaria Incidence | Not applicable | Not yet recruiting | University of North Carolina, Chapel Hill | 1296 | 2027-01-01 | 2026-08-19 |
| Study Comparing Several Drugs to Understand Which Work Against Cutaneous Leishmaniasis (CL) Sodium Stibogluconate (SSG), Miltefosine, Miltefosine + Paromomycin - Cutaneous Leihmaniasis | Phase 3 | Not yet recruiting | Institute of Tropical Medicine, Belgium | 900 | 2027-01-01 | 2026-03-10 |
| Immersive Technology Headsets to Reduce Procedural Pain and Anxiety: Feasibility and Effects in Cutaneous Leishmaniasis Patients in Pakistan Virtual Reality - Cutaneous Leishmaniasis, Pain | Not applicable | Not yet recruiting | Stanford University | 15 | 2027-01-01 | 2026-10-05 |
| An Observational Pregnancy Safety Study in Women Who Were Exposed to the Drug Nifurtimox During Pregnancy to Learn About the Risk of Pregnancy Complications and About the Mother's and Baby's Health Nifurtimox (BAYA2502) - Chagas Disease | Not yet recruiting | Bayer | 50 | 2026-12-31 | 2026-07-06 | |
| Nitazoxanide for Treatment of Cryptosporidium in Children Nitazoxanide, Placebo - Cryptosporidiosis | Phase 3 | Not yet recruiting | Johns Hopkins Bloomberg School of Public Health | 480 | 2026-12-30 | 2026-09-28 |
| Integrating the Guardian Spatial Emanator Within AVENIR II Spatial Emanator - Malaria | Not applicable | Not yet recruiting | University of California, San Francisco | 150000 | 2026-12-01 | 2026-07-22 |
| This is a Clinical Study to Assess Whether the Combination of SJ733 and Tafenoquine Will be a Safe and Rapidly Acting Anti-malarial for the Radical Cure of P. Vivax Malaria SJ733/TQ placebo, CQ/TQ Placebo, CQ/TQ - Malaria, Malaria Vivax | Phase 2 | Not yet recruiting | R. Kiplin Guy | 104 | 2026-12-01 | 2026-10-21 |
| Positron Emission Tomography and Organ-Specific Changes in Participants Co-Enrolled in NIH Studies of Plasmodium Vivax Controlled Human Malaria Infection 18F-fluorodeoxyglucose-positron emission tomography/computed tomography scan - Healthy Volunteer, Malaria | Not applicable | Not yet recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 45 | 2026-11-15 | 2026-11-10 |
| Malaria CVD 36000; Gates INV090205 PfSPZ Challenge (NF54), Wearable Biosensor Devices, Placebo - Malaria (Plasmodium Falciparum) | Phase 1 | Not yet recruiting | University of Maryland, Baltimore | 32 | 2026-11-01 | 2026-09-09 |
| A Clinical Study of Piperaquine, Pyronaridine, and Artesunate Administered in Combination in Healthy Adults Piperaquine, Artesunate-pyronaridine (Pyramax), Piperaquine and artesunate-pyronaridine (Pyramax) - Malaria | Phase 1 | Not yet recruiting | University of Oxford | 24 | 2026-11-01 | 2026-08-05 |
| Humanitarian Evaluation of Spatial Emanators for Malaria Control Guardian™ long-lasting spatial emanators - Malaria Infection | Phase 4 | Not yet recruiting | The Mentor Initiative | 32584 | 2026-10-26 | 2026-10-21 |
| Ethiopian Antimalarial Therapeutic Efficacy Study 2026 Artemether-Lumefantrine + Primaquine and Chloroquine + Primaquine - Plasmodium Vivax Malaria Without Complication, Plasmodium Falciparum Malaria (Uncomplicated) | Not yet recruiting | Ethiopian Public Health Institute | 1200 | 2026-10-20 | 2026-09-25 | |
| Factors Influencing Adoption of a Novel Malaria Treatment in Côte d'Ivoire, Ghana, and Rwanda Malaria | Not yet recruiting | Novartis Pharmaceuticals | 184 | 2026-10-20 | 2026-10-27 | |
| A Phase 2A Study of a Novel Antimalarial Pyrrolidinamide in Adult Patients With Uncomplicated P. Falciparum Malaria GSK3772701 600 mg, GSK3772701 900 mg, GSK3772701 150 mg - Malaria, Falciparum | Phase 2 | Recruiting | GlaxoSmithKline | 70 | 2026-10-07 | 2026-11-10 |
| Assessment of the Risk of Zoonotic Infections in Prisons in French Guiana Q Fever, Leptospirosis | Not yet recruiting | Centre Hospitalier de Cayenne | 450 | 2026-10-01 | 2026-10-19 |
Showing 20 of 1851. Sign in to see all of them.
Malaria (1137) · Malaria, Falciparum (451) · Malaria, Vivax (123) · Leishmaniasis, Cutaneous (102) · Chagas Disease (73) · Leishmaniasis (71) · Anemia (66) · HIV Infections (62) · Leishmaniasis, Visceral (61) · Diarrhea (38) · Acquired Immunodeficiency Syndrome (35) · Disease (34) · Trichomonas Infections (33) · Cryptosporidiosis (32) · Infections (32)
Parasitic Diseases (1827) · Infections (1819) · Vector Borne Diseases (1672) · Mosquito-Borne Diseases (1382) · Euglenozoa Infections (301) · Malaria (244) · Pathological Conditions, Signs and Symptoms (224) · Pathologic Processes (156) · Skin and Connective Tissue Diseases (154) · Skin Diseases, Infectious (153) · Skin Diseases (152) · Skin Diseases, Parasitic (147) · Urogenital Diseases (130) · Leishmaniasis (128)
Artemether, Lumefantrine Drug Combination (164) · fanasil, pyrimethamine drug combination (100) · Primaquine (92) · Chloroquine (87) · Artesunate (73) · Amodiaquine (57) · miltefosine (39) · amodiaquine, artesunate drug combination (38) · tafenoquine (34) · Azithromycin (30) · Saline Solution (29) · Mefloquine (27) · Pyrimethamine (27) · pyronaridine tetraphosphate, artesunate drug combination (26) · Meglumine Antimoniate (25)
National Institute of Allergy and Infectious Diseases (NIAID) (146) · University of Oxford (127) · London School of Hygiene and Tropical Medicine (116) · Medicines for Malaria Venture (59) · GlaxoSmithKline (55) · U.S. Army Medical Research and Development Command (53) · University of California, San Francisco (38) · Centers for Disease Control and Prevention (37) · Drugs for Neglected Diseases (34) · Institute of Tropical Medicine, Belgium (34) · Novartis Pharmaceuticals (31) · Sanaria Inc. (29) · Menzies School of Health Research (26) · Radboud University Medical Center (25) · PATH (24)
United States (214) · Kenya (123) · Burkina Faso (119) · Uganda (115) · Mali (103) · Tanzania (94) · Brazil (85) · United Kingdom (75) · Ghana (65) · Thailand (56) · Democratic Republic of the Congo (50) · Ethiopia (46) · Malawi (45) · Colombia (44) · France (43)
Patrick E Duffy, M.D. (14) · Shyam Sundar, MD (9) · Grant Dorsey, MD, PhD (8) · Kassoum Kayentao, MD, MPH, PhD (7) · Rick M Fairhurst, M.D. (7) · Salim Abdulla, MD, PhD (7) · Teun Bousema, PhD (7) · Francois Nosten, MD (6) · James McCarthy, Prof (6) · Sara A Healy, M.D. (6) · Adrian VS Hill, D.Phil, FRCP (5)
PMID 39324693, PMID 23433102, PMID 34585740, PMID 25421474, PMID 26666916, PMID 39787798, PMID 28081133, PMID 39377226, PMID 28193647, PMID 28379954, PMID 28495354, PMID 31932368, PMID 33289099, PMID 35664997, PMID 35945599, PMID 36534705, PMID 37790581, PMID 38115002, PMID 38418982, PMID 40245769, PMID 41014333, PMID 41176969, PMID 16928995, PMID 18828899, PMID 19558654, PMID 19641203, PMID 21443960, PMID 21849081, PMID 22993389, PMID 23526949, PMID 23877689, PMID 23899517, PMID 23962071, PMID 24035558, PMID 24206649, PMID 24885993, PMID 24970846, PMID 25211344, PMID 25425434, PMID 25877962, PMID 26292027, PMID 26292257, PMID 26303805, PMID 26881924, PMID 26917051, PMID 27143666, PMID 27695088, PMID 28472957, PMID 28637923, PMID 29324864
2016 (6), 2015 (4), 2019 (4), R01HD068174 (4), R01AI141444 (3), U19AI065866 (3), 2018 (2), P01HD059454 (2), R01AI110478 (2), R01NS074409 (2), U01AI065683 (2), U01AI068632 (2), U01CI000211 (2), U19AI089674 (2), U19AI089683 (2)