3 completed, 3 not yet recruiting, 2 withdrawn, 1 recruiting. 5 Phase 2, 4 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Not yet recruiting 3, Recruiting 1, Withdrawn 1 |
| Phase 1 | 4 | Completed 3, Withdrawn 1 |
| Phase 3 | 1 | Not yet recruiting 1 |
Follow oxfendazole: new trials by email Literature Review of oxfendazole trials Research Report on oxfendazole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oxfendazole in Mild Parenchymal Brain Cysticercosis Oxfendazole single dose, Oxfendazole three doses, albendazole plus praziquantel regime - Brain Cysticercosis | Phase 2 / Phase 3 | Not yet recruiting | Universidad Peruana Cayetano Heredia | 544 | 2026-12-01 | 2026-05-01 |
| One and Two Doses of Oxfendazole Versus a Schedule of Two Doses of Triclabendazole in Chronic Fascioliasis Oxfendazole, Triclabendazole - Fascioliasis | Phase 2 | Not yet recruiting | Universidad Peruana Cayetano Heredia | 336 | 2026-08-15 | 2026-06-03 |
| A Safety and Efficacy Study of Different Doses of Oxfendazole Compared to a Single Dose of Albendazole to Treat Trichuris Trichiura Infection in Adults Albendazole, Oxfendazole - Trichuriasis | Phase 2 | Recruiting | Asociacion Benefica Prisma | 249 | 2024-09-07 | 2026-07-28 |
| Efficacy of Oxfendazole in the Treatment of Trichuris Trichiura Infection in Adults Oxfendazole, Albendazole - Trichuris Infection | Phase 2 | Not yet recruiting | Oxfendazole Development Group | 250 | 2024-07-01 | 2023-11-08 |
| PK, Safety and Tolerability of Single and Multiple Doses of Oxfendazole Tablets Oxfendazole, Placebo - Filariasis | Phase 1 | Completed | Swiss Tropical & Public Health Institute | 30 | 2022-04-21 | 2022-12-20 |
| Study of the Efficacy of Oxfendazole Compared to Albendazole in the Treatment of Trichuris Trichiura Infection in Adults oxfendazole, albendazole - Helminthiasis | Phase 2 | Withdrawn | Johns Hopkins Bloomberg School of Public Health | 2019-11-01 | 2019-08-15 | |
| Multiple Ascending Dose Study of Oxfendazole in Healthy Adult Volunteers Oxfendazole - Helminthic Infection | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 36 | 2017-05-12 | 2019-12-17 |
| Single Ascending Dose Safety Study of Oxfendazole oxfendazole, placebo - Tenia Solium Infection | Phase 1 | Withdrawn | Johns Hopkins Bloomberg School of Public Health | 2016-08-01 | 2016-08-30 | |
| Phase I Trial Evaluating the Safety and Pharmacokinetics of Oxfendazole Oxfendazole, Placebo - Neurocysticercosis | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 70 | 2014-11-17 | 2020-11-02 |
Neurocysticercosis (3) · Taeniasis (2) · Trichuriasis (2) · Cysticercosis (1) · Fascioliasis (1) · Filariasis (1) · Helminthiasis (1) · Hookworm Infections (1) · Neglected Diseases (1) · Onchocerciasis (1) · Parasitic Diseases (1) · Trematode Infections (1)
Johns Hopkins Bloomberg School of Public Health (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · Universidad Peruana Cayetano Heredia (2) · Asociacion Benefica Prisma (1) · Oxfendazole Development Group (1) · Swiss Tropical & Public Health Institute (1)
United States (2) · Peru (1) · Tanzania (1)
Hector H Garcia, MD, PhD (2) · Robert H Gilman, MD (2) · Armando E Gonzalez, DVM, PhD (1) · Daniel Paris (1) · Hector H Garcia, MD PhD (1) · Lourdes Rodriguez, MD (1) · Maribel Paredes Olortegui, MPH (1) · Miguel M Cabada, MD MSc (1) · Richard J Horton, MB BChir, MRCGP, FFPM (1) · Said Jongo (1)
PMID 30745383, PMID 32816721, PMID 41662151, PMID 41705834, PMID 8615453, PMID 9364715, PMID 9840607
U01AI155323 (1)