19 completed, 5 terminated, 4 unknown, 3 recruiting. 33 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 33 | Completed 19, Terminated 5, Unknown 4, Recruiting 3, Not yet recruiting 1, Withdrawn 1 |
Follow Cecal Diseases: new trials by email Literature Review of Cecal Diseases trials Research Report on Cecal Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Povidone-iodine Irrigation for Prevention of Intra-abdominal Abscess in Pediatric Perforated Appendicitis: a Multi-center Stepped Wedge Cluster Randomized Study Irrigation with PVI, Usual care - Acute, Perforated Appendicitis | Phase 4 | Not yet recruiting | The University of Texas Health Science Center, Houston | 1750 | 2027-03-01 | 2025-02-10 |
| Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™) CYTALUX™ (pafolacianine) - Gastrointestinal Cancer, Gastric Cancer | Phase 4 | Recruiting | Cedars-Sinai Medical Center | 15 | 2025-09-05 | 2026-11-02 |
| APPI-Cost Trial for Perforated Appendicitis PVI, Usual Care - Perforated Appendicitis | Phase 4 | Recruiting | The University of Texas Health Science Center, Houston | 346 | 2025-04-07 | 2025-12-11 |
| Magnesium Sulfate in Children Undergoing Laparoscopic Appendectomy Intravenous magnesium sulfate, Normal saline infusion - Opioid Consumption, Multimodal Analgesia | Phase 4 | Recruiting | Medical University of Warsaw | 188 | 2024-09-09 | 2026-08-20 |
| Sugammadex vs Neostigmine Reversal in Pediatric Appendectomy Sugammadex, Neostigmine/Glycopyrrolate - Appendicitis, Surgery | Phase 4 | Terminated | Emory University | 22 | 2023-07-19 | 2025-09-30 |
| Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSF Multiple standard of care antibiotics for appendicitis, at physicians' discretion - Appendicitis | Phase 4 | Terminated | University of California, San Francisco | 42 | 2023-06-06 | 2026-10-27 |
| Lidocaine VS Hemodynamic, Metabolic and Hormonal Response Intravenous lidocaine, Normal saline infusion - Hemodynamic Response, Acute Appendicitis | Phase 4 | Completed | Medical University of Warsaw | 132 | 2022-03-12 | 2023-10-31 |
| Role of Delay and Antibiotics on Perforation Rate While Waiting Appendectomy Antibiotics, cefuroxime and metronidazole, No antibiotics, urgent schedule - Appendicitis | Phase 4 | Completed | Helsinki University Central Hospital | 1800 | 2020-05-18 | 2023-07-11 |
| Antibiotic Duration in Post-appendectomy Abscess ampicillin/clavulanate - Complicated Appendicitis, Perforated Appendicitis | Phase 4 | Terminated | Phoenix Children's Hospital | 7 | 2019-05-01 | 2024-03-08 |
| Intravenous Lidocaine in Children Undergoing Laparoscopic Appendectomy Lidocaine - Acute Appendicitis, Postoperative Pain | Phase 4 | Completed | Medical University of Warsaw | 74 | 2019-03-22 | 2020-05-19 |
| Once Daily Metronidazole for Perforated Appendicitis Metronidazole - Appendicitis | Phase 4 | Withdrawn | Ahmed Nasr | 2019-01-01 | 2017-07-21 | |
| COMPARISON OF TRANSVERSUS ABDOMINIS PLANE BLOCK, LOCAL ANESTHETIC INJECTION TO THE PORT SITES AND INTRAPERITONEAL LOCAL ANESTHESIA APPLICATIONS IN POSTOPERATIVE PAIN MANAGEMENT IN PATIENTS WITH LAPAROSCOPIC APPENDECTOMY Bupivacaine - Postoperative Pain | Phase 4 | Completed | Fatih Sultan Mehmet Training and Research Hospital | 3 | 2018-11-01 | 2021-03-23 |
| Acute Appendicitis: Active Observation With and Without Antibiotics Antibiotic treatment (Piperacillin/Tazobactam, 4 gram x 3), followed by 8-10 days of out-hospital oral antibiotic treatment (Ciprofloxacin 500 mgx2,Flagyl 400 mgx3)., Active observation - Appendicitis | Phase 4 | Completed | Göteborg University | 126 | 2018-05-15 | 2022-08-16 |
| Wound Infiltration With Local Anesthetic Agent for Laparoscopic Appendectomy in Adult Bupivacaine - Appendicitis Acute | Phase 4 | Completed | National Taiwan University Hospital | 47 | 2018-04-23 | 2020-04-27 |
| Optimal Care of Complicated Appendicitis Early Appendectomy, Interval Appendectomy, Antibiotics - Appendicitis, Perforated Appendicitis | Phase 4 | Completed | University of Michigan | 40 | 2017-06-29 | 2023-11-28 |
| Two Different Antibiotics Versus One Antibiotic for Pediatric Perforated Appendicitis Piperacillin, Tazobactam Drug Combination - Perforated Appendicitis, Postoperative Infection | Phase 4 | Completed | Phoenix Children's Hospital | 162 | 2017-05-22 | 2024-01-12 |
| Comparison of Medical and Surgical Treatment of Uncomplicated Acute Appendicitis in Children Piperacillin/Tazobactam, Surgical Treatment - Appendicitis | Phase 4 | Completed | NYU Langone Health | 39 | 2016-12-01 | 2022-01-21 |
| Initial Non-operative Treatment Strategy Versus Appendectomy Treatment Strategy for Simple Appendicitis in Children Augmentin + Gentamicin, Appendectomy - Appendicitis | Phase 4 | Unknown | Ramon Gorter | 302 | 2016-12-01 | 2023-10-23 |
| A Trial to Assess the Efficacy and Safety of Morinidazole in Patients With Appendicitis morinidazole - Appendicitis | Phase 4 | Unknown | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 614 | 2016-09-01 | 2017-12-21 |
| Appendicectomy Skin Closure Technique: Changing Paradigms (ASC) Continuous intradermic stitch, Separated stitches - Appendicitis | Phase 4 | Completed | María Valeria Jiménez Baez | 200 | 2015-04-01 | 2016-05-27 |
Showing 20 of 33. Sign in to see all of them.
Appendicitis (31) · Pain, Postoperative (3) · Abdominal Abscess (2) · Appendiceal Neoplasms (2) · Cholecystitis (2) · Diverticulitis (2) · Esophageal Neoplasms (2) · Peritonitis (2) · Stomach Neoplasms (2) · Abscess (1) · Agnosia (1) · Anus Neoplasms (1) · Bile Duct Neoplasms (1) · Carcinoma, Hepatocellular (1) · Colonic Neoplasms (1)
Digestive System Diseases (33) · Gastrointestinal Diseases (33) · Intestinal Diseases (33) · Gastroenteritis (31) · Infections (30) · Intraabdominal Infections (30) · Pathological Conditions, Signs and Symptoms (9) · Pathologic Processes (7) · Neurologic Manifestations (5) · Signs and Symptoms (5) · Biliary Tract Diseases (3) · Gallbladder Diseases (3) · Pain (3) · Peritoneal Diseases (3)
Metronidazole (7) · Appendectomy (5) · Piperacillin, Tazobactam Drug Combination (4) · Amoxicillin-Potassium Clavulanate Combination (3) · Anti-Bacterial Agents (2) · Bupivacaine (2) · Ceftriaxone (2) · Ciprofloxacin (2) · Clavulanic Acid (2) · Morphine (2) · Piperacillin (2) · Tazobactam (2) · Tigecycline (2) · Amoxicillin (1) · Ampicillin (1)
Medical University of Warsaw (3) · Phoenix Children's Hospital (2) · The University of Texas Health Science Center, Houston (2) · Wyeth is now a wholly owned subsidiary of Pfizer (2) · A.O. Ospedale Papa Giovanni XXIII (1) · Ahmed Nasr (1) · Baylor College of Medicine (1) · Cedars-Sinai Medical Center (1) · Emory University (1) · Fatih Sultan Mehmet Training and Research Hospital (1) · GERCOR - Multidisciplinary Oncology Cooperative Group (1) · Göteborg University (1) · Helsinki University Central Hospital (1) · Hospital Infantil Albert Sabin (1) · Jiangsu Hansoh Pharmaceutical Co., Ltd. (1)
United States (11) · Finland (3) · Italy (3) · Poland (3) · Brazil (2) · China (2) · France (2) · Taiwan (2) · Turkey (Türkiye) (2) · Argentina (1) · Australia (1) · Canada (1) · Chile (1) · Denmark (1) · Germany (1)
Ahmed Nasr (1) · Andrea Biscardi, MD (1) · Asieh Golozar, MD (1) · Chih-Yang Hsiao, M.D. (1) · Craig Egan, MD (1) · Dalya Ferguson, MD, MS (1) · Donagh A Healy, MB (1) · Eleonora Giorgini, MD (1) · Ernst van Heurn, MD PhD (1) · Franco Baldoni, MD (1) · Gianluca Senatore, MD (1) · Gregorio Tugnoli, MD (1)
PMID 18723709, PMID 20670293, PMID 22021722, PMID 22439781, PMID 24646528, PMID 27283187, PMID 27582784, PMID 29146647, PMID 33397287, PMID 34580704, PMID 35982198, PMID 37717589, PMID 39794723, PMID 41226876, PMID 42157906
2019 (1), K12TR004908 (1)