7 completed, 4 recruiting, 2 unknown, 1 not yet recruiting. 16 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 16 | Completed 7, Recruiting 4, Unknown 2, Not yet recruiting 1, Terminated 1, Withdrawn 1 |
Follow Cardiogenic Shock: new trials by email Literature Review of Cardiogenic Shock trials Research Report on Cardiogenic Shock
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Capital Offload-Shock Immediate renal replacement therapy - Hypervolemia, Cardiogenic Shock | Phase 4 | Not yet recruiting | Ottawa Heart Institute Research Corporation | 456 | 2026-12-01 | 2026-10-30 |
| Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure Ketone Monoester (KE) - Acute Heart Failure (AHF), Cardiogenic Shock | Phase 4 | Recruiting | Institute for Clinical and Experimental Medicine | 12 | 2026-04-04 | 2026-04-14 |
| Accelerated vs. Standard Continuous Renal Replacement Therapy for Patients With Cardiogenic Shock Undergoing Veno-arterial ExtraCorporeal Membrane Oxygenator Early initiation of continuous renal replacement therapy, Standard initiation of continuous renal replacement therapy - Cardiogenic Shock, Acute Kidney Injury | Phase 4 | Recruiting | Samsung Medical Center | 408 | 2024-12-31 | 2026-01-05 |
| Revascularization Strategy of Multivessel Disease for Patients with Acute Myocardial Infarction Complicated by Cardiogenic Shock Undergoing Veno-arterial Extracorporeal Membrane Oxygenator Culprit lesion only PCI, Immediate multi-vessel PCI - Cardiogenic Shock, Acute Myocardial Infarction | Phase 4 | Recruiting | Samsung Medical Center | 560 | 2022-11-16 | 2024-11-06 |
| Clinical Outcome and Cost-effectiveness of Reduced Noradrenaline by Using a Lower Blood Pressure Target in Patients With Cardiogenic Shock From Acute Myocardial Infarction Reduced noradrenaline use - Cardiogenic Shock, Myocardial Infarction | Phase 4 | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 776 | 2022-10-01 | 2026-03-27 |
| Study on Early Intra-aortic Balloon Pump Placement in Acute Decompensated Heart Failure Complicated by Cardiogenic Shock Early intra-aortic balloon pump (IABP) implantation, Standard of care as vasoactive agent - Cardiogenic Shock | Phase 4 | Terminated | Niguarda Hospital | 100 | 2020-05-04 | 2024-10-23 |
| Comparison of ARNI to Alternate Oral Vasodilator Therapies in Patients With Low Cardiac Output Sacubitril-Valsartan, Standard Oral Vasodilators - Cardiogenic Shock | Phase 4 | Withdrawn | The Cleveland Clinic | 2019-11-25 | 2020-10-05 | |
| Evaluation of Early CRRT InTerventions in Patients With ECMO(ELITE) Simultaneous CRRT, Conventional-indication CRRT, Esmolol - Cardiogenic Shock | Phase 4 | Completed | Beijing Anzhen Hospital | 131 | 2018-12-18 | 2024-04-24 |
| Dual Antiplatelet Therapy For Shock Patients With Acute Myocardial Infarction Cangrelor, Ticagrelor - Acute Myocardial Infarction, Cardiogenic Shock | Phase 4 | Completed | Faculty Hospital Kralovske Vinohrady | 605 | 2018-08-01 | 2025-04-02 |
| Efficacy and Safety on Heart Rate Control With Ivabradine on Cardiogenic Shock Ivabradine Oral Tablet, Standard of Care treatment - Cardiogenic Shock | Phase 4 | Unknown | Hospital Universitario Ramon y Cajal | 22 | 2018-05-01 | 2018-02-19 |
| Effect of Ivabradine in Stage D HF/Cardiogenic Shock Patients on Dobutamine Ivabradine, Placebo - Heart Failure, Cardiogenic Shock | Phase 4 | Unknown | Loyola University | 40 | 2018-03-15 | 2019-05-23 |
| Milrinone Versus Dobutamine in Critically Ill Patients Milrinone, Dobutamine - Low Cardiac Output Syndrome, Cardiogenic Shock | Phase 4 | Completed | Ottawa Heart Institute Research Corporation | 192 | 2017-08-30 | 2020-06-30 |
| Clinical Study of Extra-Corporal Life Support in Cardiogenic Shock Complicating Acute Myocardial Infarction Extra-Corporal Life Support (ECLS) - Cardiogenic Shock | Phase 4 | Completed | LMU Klinikum | 42 | 2015-11-01 | 2019-10-14 |
| Culprit Lesion Only PCI Versus Multivessel PCI in Cardiogenic Shock Immediate multivessel PCI, Culprit Lesion only PCI - Cardiogenic Shock, Acute Myocardial Infarction | Phase 4 | Completed | University of Luebeck | 706 | 2013-04-01 | 2017-11-09 |
| Study Comparing the Efficacy and Tolerability of Epinephrine and Norepinephrine in Cardiogenic Shock epinephrine perfusion, norepinephrine perfusion - Cardiogenic Shock | Phase 4 | Completed | Central Hospital, Nancy, France | 58 | 2011-09-01 | 2019-02-01 |
| Levosimendan in Acute Heart Failure Following Acute Myocardial Infarction. levosimendan, placebo, - Myocardial Infarction, Heart Failure | Phase 4 | Completed | Oslo University Hospital | 61 | 2006-06-01 | 2012-06-26 |
Shock, Cardiogenic (16) · Heart Failure (3) · Myocardial Infarction (3) · Acute Coronary Syndrome (1) · Acute Kidney Injury (1) · Cardiac Output, Low (1) · Edema (1) · Infarction (1) · Ketosis (1) · Pulmonary Edema (1) · Tachycardia (1)
Cardiovascular Diseases (16) · Heart Diseases (16) · Ischemia (16) · Myocardial Ischemia (16) · Necrosis (16) · Pathologic Processes (16) · Pathological Conditions, Signs and Symptoms (16) · Shock (16) · Vascular Diseases (16) · Infarction (15) · Myocardial Infarction (13) · Signs and Symptoms (2) · Acid-Base Imbalance (1) · Acidosis (1) · Arrhythmias, Cardiac (1)
Ivabradine (2) · Standard of Care (2) · Catecholamines (1) · Dobutamine (1) · Drug Implants (1) · Milrinone (1) · N(1)-methyl-2-lysergic acid diethylamide (1) · Simendan (1) · Ticagrelor (1) · Vasoconstrictor Agents (1) · cangrelor (1) · esmolol (1) · sacubitril and valsartan sodium hydrate drug combination (1)
Ottawa Heart Institute Research Corporation (2) · Samsung Medical Center (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Beijing Anzhen Hospital (1) · Central Hospital, Nancy, France (1) · Faculty Hospital Kralovske Vinohrady (1) · Hospital Universitario Ramon y Cajal (1) · Institute for Clinical and Experimental Medicine (1) · LMU Klinikum (1) · Loyola University (1) · Niguarda Hospital (1) · Oslo University Hospital (1) · The Cleveland Clinic (1) · University of Luebeck (1)
Germany (3) · Canada (2) · Czechia (2) · France (2) · South Korea (2) · United States (2) · China (1) · Italy (1) · Netherlands (1) · Norway (1) · Poland (1) · Slovakia (1) · Spain (1)
Benjamin M Hibbert, MD, PhD (1) · Deepak L Bhatt, MD, MPH, MBA. (1) · Eugenia Raichlin, MD (1) · Holger Thiele, MD (1) · Jeong Hoon Yang, MD (1) · Jianzeng Dong, PhD., Md. (1) · Randall Starling, MD, MPH (1) · Simon Parlow, MD, FRCPC (1) · Stefan Brunner, MD (1) · Steffen Massberg, MD (1) · Trygve Husebye, MD, (1) · Zuzana Motovska, MD, PhD. (1)
PMID 23288914, PMID 25390695, PMID 26856213, PMID 26856228, PMID 28821512, PMID 29083953, PMID 29976291, PMID 30145971, PMID 31072581, PMID 31167601, PMID 31472039, PMID 32151161, PMID 32845312, PMID 32883104, PMID 32894227, PMID 33119664, PMID 33647946, PMID 34347952, PMID 34376218, PMID 34713704, PMID 35261289, PMID 35986410, PMID 36229091, PMID 36948733, PMID 38335531, PMID 40162941, PMID 40986817, PMID 41031405, PMID 41543923, PMID 42425722
2009 (1), 2018 (1)