4 completed, 2 terminated, 1 recruiting, 1 unknown. 9 Phase 2, 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 4, Terminated 2, Recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 1 | 2 | Completed 1, Terminated 1 |
| Phase 3 | 1 | Terminated 1 |
Follow Cardiac Disease: new trials by email Literature Review of Cardiac Disease trials Research Report on Cardiac Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Factor VIII Inhibitor Bypass Activity (FEIBA) Versus Fresh Frozen Plasma As First Line Therapy For Bleeding After Cardiac Surgery FEIBA, FFP - Cardiac Disease, Surgery | Phase 2 | Recruiting | Northwell Health | 140 | 2025-11-03 | 2026-03-11 |
| Effectiveness of Different Fibrinogen Preparations in Restoring Clot Firmness FibCLOT, RiaSTAP - Hypofibrinogenemia, Surgical Blood Loss | Phase 2 | Completed | IRCCS Policlinico S. Donato | 40 | 2023-03-20 | 2024-02-28 |
| FEIBA to Optimize Postcardiopulmonary Bypass Hemostasis in Pediatric Cardiac Patients FEIBA, Placebo - Cardiac Disease | Phase 2 | Withdrawn | Mayo Clinic | 2021-10-01 | 2022-12-05 | |
| Low Dose Continuous Furosemide Effect on Cardiac Surgery Patients With Kidney Dysfunction Furosemide in 0.9 % NaCl 100 Mg/100 mL (1 mg/mL), NaCl 0.9% - Chronic Kidney Disease, Cardiac Disease | Phase 2 | Completed | National Cardiovascular Center Harapan Kita Hospital Indonesia | 90 | 2021-05-27 | 2024-01-05 |
| A Dose Ascending Study to Evaluate the Safety of NH002 as a Contrast Agent in Cardiac Echocardiography NH002 (Perflutren Lipid Microspheres) Injectable Suspension, Echocardiogram - Cardiac Disease | Phase 1 / Phase 2 | Completed | Trust Bio-sonics, Inc. | 36 | 2019-11-04 | 2025-11-18 |
| Lidocaine as an Endotracheal Tube (ETT) Cuff Media 1.8% lidocaine plus 0.76% sodium bicarbonate, Air - Cardiac Disease | Phase 2 | Completed | Mayo Clinic | 32 | 2018-07-27 | 2019-09-27 |
| CO as a Stimulant for Mitochondrial Biogenesis in Human Cardiac Muscle 200ppm CO for one hour, Control - Cardiac Disease, Mitochondrial Biogenesis | Phase 1 / Phase 2 | Terminated | John J Freiberger | 1 | 2014-02-01 | 2016-05-19 |
| Nitrite Effects on Cardiac Muscle in CABG Sodium Nitrite, 0.9% Sodium-chloride - Coronary Artery Disease, Atherosclerosis | Phase 2 | Unknown | University of East Anglia | 75 | 2013-01-21 | 2019-06-28 |
| Attenuation Corrected Cardiac SPECT Using the GE Hawkeye Camera System GE Attenuation Corrected Hawkeye Camera - Cardiac Disease | Phase 2 / Phase 3 | Terminated | Mayo Clinic | 608 | 2001-07-01 | 2015-04-23 |
Heart Diseases (9) · Hemorrhage (2) · Afibrinogenemia (1) · Atherosclerosis (1) · Blood Loss, Surgical (1) · Chest Pain (1) · Coronary Artery Disease (1) · Diabetes Mellitus (1) · Myocardial Infarction (1) · Postoperative Hemorrhage (1) · Renal Insufficiency, Chronic (1) · Vascular Diseases (1)
Cardiovascular Diseases (9) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Myocardial Ischemia (2) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Blood Coagulation Disorders (1) · Blood Coagulation Disorders, Inherited (1) · Chronic Disease (1) · Coagulation Protein Disorders (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Coronary Disease (1) · Disease Attributes (1) · Endocrine System Diseases (1) · Female Urogenital Diseases (1)
Sodium Chloride (2) · anti-inhibitor coagulant complex (2) · Air (1) · Echocardiography (1) · Fibrinogen (1) · Furosemide (1) · Lidocaine (1) · Sodium Bicarbonate (1) · Sodium Nitrite (1)
Mayo Clinic (3) · IRCCS Policlinico S. Donato (1) · John J Freiberger (1) · National Cardiovascular Center Harapan Kita Hospital Indonesia (1) · Northwell Health (1) · Trust Bio-sonics, Inc. (1) · University of East Anglia (1)
United States (4) · Indonesia (1) · Italy (1) · Taiwan (1) · United Kingdom (1)
Bambang Widyantoro, PhD (1) · Chung-Lieh Hung (1) · Elena Ashikhmina, MD, PhD (1) · Marco Ranucci, MD (1) · Michael P Frenneaux, MD, FRCP (1) · Pey-Jen Yu (1) · Todd D Miller, MD (1) · Troy G Seelhammer, MD (1) · Wen-Chung Yu (1)