22 completed, 9 terminated, 7 unknown, 6 recruiting. 52 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 52 | Completed 22, Terminated 9, Unknown 7, Recruiting 6, Withdrawn 5, Not yet recruiting 2, Enrolling by invitation 1 |
Follow Burns: new trials by email Literature Review of Burns trials Research Report on Burns
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Safety and Efficacy of Dehydrated Human Amnion-Intermediate-Chorion Membrane (dHAICM) Allograft in Treatment of Partial Thickness Thermal Burns Amnion-Intermediate-Chorion, Standard of Care (SOC) - Partial Thickness Burn | Phase 4 | Withdrawn | Cellution Biologics | 2026-10-01 | 2026-08-27 | |
| Pharmacokinetic Analysis of Cefiderocol in Patients With Acute Burn Injuries Cefiderocol - Drug Clearance After Severe Burn Injury | Phase 4 | Recruiting | University of Tennessee | 12 | 2026-02-16 | 2026-03-12 |
| Evaluating Whether Intact Fish Skin Graft Can Decrease the Need for Autograft in the Treatment of Deep Partial-Thickness Burns Intact fish skin graft, autograft - Partial-thickness Burn Wounds | Phase 4 | Enrolling by invitation | Kerecis Ltd. | 65 | 2026-01-01 | 2026-01-08 |
| Optimizing Fluid Resuscitation in Adults With Major Burns: A Randomized Trial of Burn Navigator™ Versus Parkland Formula Burn Navigator, Resuscitation (Voluven) - Resuscitation, Burn | Phase 4 | Not yet recruiting | Alnas Hospital | 62 | 2026-01-01 | 2025-12-29 |
| Perioperative Lidocaine Infusions for the Management of Pain From Burn Injury IV Lidocaine, IV Saline - Pain Management, Burn Injury | Phase 4 | Not yet recruiting | University of Washington | 20 | 2025-04-01 | 2025-04-04 |
| Burn Study- Tranexamic Acid Versus Thrombin in Split Thickness Skin Graft Tranexamic acid, Thrombin JMI, skin graft - Burns, Skin Graft Complications | Phase 4 | Recruiting | University of Kansas Medical Center | 62 | 2024-07-11 | 2026-08-27 |
| Low-Dose Ketamine Infusion During Burn Wound Care Ketamine, 0.9% NaCl - Burn, Pain | Phase 4 | Recruiting | University of Tennessee | 140 | 2024-07-08 | 2024-12-13 |
| Oliceridine in Patients With Acute Burn Injuries Oliceridine, Historical opioid use - Acute Pain, Burns | Phase 4 | Completed | University of Tennessee | 31 | 2023-04-01 | 2023-10-26 |
| Vitamin D Deficiency in Adults Following a Major Burn Injury Ergocalciferol Capsules - Vitamin D Deficiency, Burns | Phase 4 | Completed | University of Texas Southwestern Medical Center | 48 | 2022-09-29 | 2025-12-15 |
| Plasma Resuscitation Without Lung Injury Pathogen-Reduced Plasma, Crystalloid Solutions - Burns | Phase 4 | Terminated | Coalition for National Trauma Research | 13 | 2022-08-17 | 2025-01-29 |
| Acute Partial Thickness Burn Study Comparing Transforming Powder Dressing to Standard of Care Dressing Altrazeal (R) Transforming Powder Dressing, Standard of Care burn dressing - Wounds and Injuries | Phase 4 | Recruiting | ULURU Inc. | 60 | 2022-05-26 | 2025-11-19 |
| Pilot Study: KeraStat® Gel for Topical Delivery of Morphine for Management of Non-Healing, Painful Open Wounds and Ulcers KeraStat® Gel with Morphine application, KeraStat® Gel application - Wound of Skin, Burns | Phase 4 | Recruiting | The Metis Foundation | 24 | 2021-05-11 | 2022-02-01 |
| Efficacy of Platelet Rich Plasma Injection Plus Fat Grafting as Compared to Fat Grafting Alone on Burn Scar by Using Vancouver Scar Scale Platelet Rich Plasma plus fat grafting - Burn | Phase 4 | Completed | Dow University of Health Sciences | 64 | 2021-03-01 | 2023-02-21 |
| The Use of a Platform Wound Device for Reducing Infection Gentamycin with Platform Wound Device - Wounds and Injury, Burn Wound | Phase 4 | Completed | The Metis Foundation | 48 | 2021-02-08 | 2022-10-14 |
| The Relationship Between Cadaveric Allograft Skin and HLA-Sensitivity in Burn Patients Skin allograft - Burns | Phase 4 | Withdrawn | Virginia Commonwealth University | 2021-02-01 | 2021-03-19 | |
| Microsurfaced Grafts in Deep Burn Wounds Split thickness skin graft, microsurfaced split thickness skin graft - Burns, Wound Heal | Phase 4 | Recruiting | CellTherX | 20 | 2021-01-04 | 2021-01-15 |
| Intraoperative Small-dose Esketamine Infusion for Pain Control in Burn Patients Esketamine, Saline - Burns | Phase 4 | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 26 | 2020-07-14 | 2020-12-24 |
| Comparison of Vitamin K Doses in Patients With Larger Burn Injuries Vitamin K - Burns | Phase 4 | Unknown | Joseph M. Still Research Foundation, Inc. | 50 | 2019-05-10 | 2021-08-25 |
| Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain Lidocaine Hydrochloride, Liposomal bupivacaine, Bupivacaine Hydrochloride - Pain, Postoperative, Burns | Phase 4 | Completed | University of Kansas Medical Center | 74 | 2019-03-18 | 2026-03-31 |
| A Randomized, Controlled Trial of the Effectiveness of Perioperative Antibiotics for Reduction of Burn Wound Bacterial Concentration Following Grafting Cefazolin, Clindamycin - Burn, Surgery | Phase 4 | Completed | Medstar Health Research Institute | 32 | 2018-05-29 | 2022-08-26 |
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Wounds and Injuries (4) · Agnosia (3) · Sunburn (3) · Hyperalgesia (2) · Neoplasm Metastasis (2) · Pain (2) · Stress Disorders, Post-Traumatic (2) · Wound Infection (2) · Acute Pain (1) · Adrenal Insufficiency (1) · Cicatrix (1) · Critical Illness (1) · Depression (1) · Dissociative Disorders (1)
Wounds and Injuries (48) · Pathological Conditions, Signs and Symptoms (14) · Signs and Symptoms (9) · Neurologic Manifestations (8) · Pathologic Processes (7) · Skin Diseases (6) · Skin and Connective Tissue Diseases (6) · Nervous System Diseases (5) · Infections (3) · Mental Disorders (3) · Neurobehavioral Manifestations (3) · Perceptual Disorders (3) · Photosensitivity Disorders (3) · Disease Attributes (2)
Sodium Chloride (5) · Bacitracin (4) · Remifentanil (3) · Silver Sulfadiazine (3) · Hydroxyethyl Starch Derivatives (2) · Ketamine (2) · Lidocaine (2) · Midazolam (2) · Sertraline (2) · Skin Transplantation (2) · Tranexamic Acid (2) · Transplantation, Autologous (2) · cerous nitrate, sulfadiazine silver drug combination (2) · ((3-methoxythiophen-2-yl)methyl)((2-(9-(pyridin-2-yl)-6-oxaspiro(4.5)decan-9-yl)ethyl))amine (1) · Acticoat (1)
Medical University of Vienna (3) · University of Kansas Medical Center (3) · University of Tennessee (3) · Association of Dutch Burn Centres (2) · Poznan University of Medical Sciences (2) · The Metis Foundation (2) · University of Zurich (2) · Alnas Hospital (1) · CellTherX (1) · Cellution Biologics (1) · Centre Hospitalier Saint Joseph Saint Luc de Lyon (1) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · Coalition for National Trauma Research (1) · Coordinación de Investigación en Salud, Mexico (1) · Dow University of Health Sciences (1)
United States (24) · Canada (4) · Austria (3) · France (3) · Netherlands (2) · Switzerland (2) · Brazil (1) · China (1) · Egypt (1) · Kazakhstan (1) · Mexico (1) · Moldova (1) · Pakistan (1) · Sweden (1) · Ukraine (1)
Dhaval Bhavsar, MD (2) · Marianne K Nieuwenhuis, PhD (2) · Astrid Chiari, MD (1) · Bernadette Nedelec, BSc, OT, PhD (1) · Brent M Kious, MD PhD (1) · Burkhard Gustorff, MD (1) · Carlee R. Lehna, PhD, APRN-BC (1) · Claus Brandigi, MD (1) · David Bracco, MD (1) · David N Herndon, MD (1) · Dhaval Bhavsar, MBBS (1) · Eric Davis, MD (1) · Frederick J Stoddard, M.D. (1) · Grzegorz Kowalski, Ph.D. (1) · Herbert B Slade, MD (1)
PMID 1052771, PMID 11855913, PMID 13571547, PMID 13934413, PMID 14209177, PMID 15273468, PMID 1572841, PMID 19165111, PMID 19397669, PMID 20828761, PMID 22040192, PMID 22373992, PMID 22842424, PMID 23578794, PMID 23641301, PMID 24365167, PMID 25619170, PMID 28623938, PMID 32366324, PMID 33350618, PMID 34216466, PMID 34688520, PMID 35141873, PMID 38767196, PMID 39375158, PMID 41212678, PMID 8884006, PMID 928463