8 completed, 4 terminated, 2 recruiting, 2 unknown. 9 Not applicable, 5 Phase 4, 2 Phase 2, 1 Early Phase 1, 1 Phase 3.
Follow Silver Sulfadiazine: new trials by email Literature Review of Silver Sulfadiazine trials Research Report on Silver Sulfadiazine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Silver Sulfadiazine With Hyaluronic Acid Versus Silver Sulfadiazine Alone in Partial-Thickness Burns Silver Sulfadiazine With Hyaluronic Acid, Silver Sulfadiazine - Partial-Thickness Burn, Thermal Burn | Not applicable | Not yet recruiting | Dr Muhammad Naveed Shahzad | 30 | 2026-02-01 | 2026-01-26 |
| Microenvironment in Patients Undergoing Non-traumatic Amputation ciNPWT, SSD - Lower Limb Amputation Above Knee | Not applicable | Recruiting | University of Aarhus | 20 | 2025-08-01 | 2026-02-12 |
| Evaluation of the Effectiveness of a Topical Medical Device in Wound Healing and Symptom Relief in the Postoperative Period of Open Excisional Hemorrhoidectomy (The Emor Study) Gel containing a Propionibacterium extract, Hyaluronic acid and silver sulfadiazine - Anus Diseases, Gastrointestinal Diseases | Phase 4 | Completed | University of Cagliari | 114 | 2025-03-04 | 2025-07-02 |
| StrataXRT for the Prevention and Treatment of Radiation Dermatitis in Breast Cancer or Head and Neck Cancer Patients Calendula Ointment, Petrolatum-Mineral Oil-Lanolin-Ceresin Ointment, Polyethylene Glycol Hydrogel - Breast Carcinoma, Head and Neck Carcinoma | Not applicable | Withdrawn | OHSU Knight Cancer Institute | 2024-01-01 | 2024-05-06 | |
| SWC for Treatment of Superficial Partial-Thickness Burns SynePure Wound Cleanser and Catasyn Advanced Technology Hydrogel, SILVADENE Cream 1% (silver sulfadiazine) - Burn Wounds | Not applicable | Terminated | Synedgen, Inc. | 2 | 2023-03-27 | 2024-12-03 |
| Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns Investigational Drug, MW-III, Silvadene® Cream 1% [Silver Sulfadiazine] - Burns | Phase 2 | Recruiting | Skingenix, Inc. | 60 | 2022-03-11 | 2026-03-16 |
| Superficial Partial-Thickness Burn Study Catasyn™ Advanced Technology Hydrogel and SynePure™ Wound Cleanser, Silver Sulfadiazine - Superficial Partial Thickness Burn | Phase 4 | Terminated | J. Peter Rubin, MD | 26 | 2021-06-11 | 2024-02-01 |
| Effectiveness of KeraStat Gel for Improved Cosmesis of Partial Thickness Burns KeraStat Gel, Silver Sulfadiazine - Partial-thickness Burn | Not applicable | Terminated | KeraNetics, LLC | 14 | 2018-08-31 | 2024-08-01 |
| Use of Nile Tilapia Fish Skin as a Xenograft for Burn Treatment: Phase III Study Nile Tilapia Fish Skin, Silver Sulfadiazine Cream 1% - Burns | Phase 3 | Completed | Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara | 115 | 2017-04-03 | 2020-01-29 |
| Study to Evaluate the Use of Tilapia Skin (Oreochromis Niloticus), in the Treatment of Burn Wounds Sulfadiazine, Silver, Skin of Nile tilapia - Burns | Phase 2 | Completed | Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara | 63 | 2016-10-05 | 2018-07-19 |
| Patients Response to Early Switch To Oral:Osteomyelitis Study oral antibiotics, intravenous antibiotics - Osteomyelitis | Early Phase 1 | Terminated | Julio Ramirez | 11 | 2014-03-06 | 2021-04-06 |
| Comparative Analysis of Cost-effectiveness of Silver Dressing in Burns Nanocrystalline silver, Silver Sulfadiazine - Second-degree Burn | Phase 4 | Completed | University of Sorocaba | 100 | 2013-11-01 | 2021-05-18 |
| To Study the Healing Effect of Silver Impregnated Activated Carbon Fiber Wound Dressing on Superficial Dermal Burn Flamazine, BCT Antimicrobial Dressing - Burns | Not applicable | Completed | Bio-medical Carbon Technology Co., Ltd. | 30 | 2012-05-01 | 2017-07-13 |
| To Study the Healing Effect of Silver Impregnated Activated Carbon Fiber Wound Dressing on Deep Dermal Burn BCT Antimicrobial Dressing, Flamazine - Burns | Not applicable | Completed | Bio-medical Carbon Technology Co., Ltd. | 30 | 2012-05-01 | 2017-07-13 |
| Early Intervention in Very Preterm Children Early parent-based speech intervention program - Prematurity, Speech Sound Disorder | Not applicable | Unknown | Erasmus Medical Center | 25 | 2011-04-01 | 2011-05-12 |
| Comparison of a Water-soluble Topical Antimicrobial to Silver Sulfadiazine in Partial Thickness Burns water-soluble therapy, silver sulfadiazine - Burn | Phase 4 | Completed | University of Virginia | 8 | 2011-04-01 | 2013-08-21 |
| Treatment of Facial Burns With Flammacerium Compared to Flammazine and the Impact of Facial Burns on Psychosocial Wellbeing ceriumnitrate silversulfadiazine (flammacerium), silversulfadiazine (flammazine) - Burns | Phase 4 | Completed | Association of Dutch Burn Centres | 154 | 2006-03-01 | 2020-02-17 |
| Topical Collagen-Silver Versus Standard Care Following Removal of Ingrown Nails oxidized regenerated cellulose collagen-silver, topical silver sulfadiazine cream - Ingrown Nail | Not applicable | Unknown | Rosalind Franklin University of Medicine and Science | 80 | 2005-11-01 | 2008-03-24 |
Burns (9) · Anus Diseases (1) · Breast Neoplasms (1) · Cicatrix (1) · Gastrointestinal Diseases (1) · Hemorrhoids (1) · Intestinal Diseases (1) · Nails, Ingrown (1) · Osteomyelitis (1) · Premature Birth (1) · Radiodermatitis (1) · Speech Sound Disorder (1) · Wounds and Injuries (1)
Bio-medical Carbon Technology Co., Ltd. (2) · Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara (2) · Association of Dutch Burn Centres (1) · Dr Muhammad Naveed Shahzad (1) · Erasmus Medical Center (1) · J. Peter Rubin, MD (1) · Julio Ramirez (1) · KeraNetics, LLC (1) · OHSU Knight Cancer Institute (1) · Rosalind Franklin University of Medicine and Science (1) · Skingenix, Inc. (1) · Synedgen, Inc. (1) · University of Aarhus (1) · University of Cagliari (1) · University of Sorocaba (1)
United States (8) · Brazil (2) · Netherlands (2) · Taiwan (2) · Denmark (1) · Italy (1) · Mexico (1) · Pakistan (1)
Eng Kean Yeong, MD (2) · David G Armstrong, DPM, PhD (1) · David Seligson, MD (1) · J. Peter Rubin, MD (1) · James H Holmes IV, MD (1) · Jonathan Black, MD (1) · Josh Walker, M.D., Ph.D. (1) · Julio Ramirez, MD (1) · Kevin Foster (1) · Luciane C Lopes, PhD (1) · Maria Elisabete A Moraes, MD (1) · Marianne K Nieuwenhuis, PhD (1) · Muhammad N Shahzad, MBBS, MCPS,FCPS,FCPS (1)
PMID 15276398, PMID 15840453, PMID 19588358, PMID 22530208, PMID 22842424, PMID 31900475, PMID 34688520, PMID 42334667, PMID 4902833, PMID 8948280