5 completed, 2 not yet recruiting, 1 recruiting, 1 terminated. 6 Phase 2, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 2, Not yet recruiting 2, Recruiting 1, Withdrawn 1 |
| Phase 3 | 3 | Completed 2, Terminated 1 |
Follow Bunionectomy: new trials by email Literature Review of Bunionectomy trials Research Report on Bunionectomy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Postsurgical Analgesia After Unilateral Bunionectomy AMT-143, Saline (NaCl 0,9 %) (placebo) - Bunionectomy, Bunion | Phase 2 | Not yet recruiting | AmacaThera Inc. | 60 | 2026-12-01 | 2026-10-22 |
| A Clinical Trial of GRT7040 in Adults With Acute Pain Following Bunionectomy GRT7040, Hydrocodone bitartrate/ acetaminophen (HB/APAP), Placebo (matched to HB/APAP) - Acute Pain, Bunionectomy | Phase 2 | Not yet recruiting | Grünenthal GmbH | 400 | 2026-09-01 | 2026-09-15 |
| Sciatic Nerve Block With ALX006 in Subjects Undergoing Bunionectomy ALX006 (bupivacaine extended-release injection), Bupivacaine Hcl 0.25% Inj, Sciatic Nerve Block - Hallux Valgus, Bunionectomy | Phase 2 | Recruiting | Rebel Medicine Inc | 60 | 2026-03-10 | 2026-05-07 |
| Phase 3, Sciatic Nerve Block With EXPAREL for Subjects Undergoing Bunionectomy Bupivacaine liposome injectable suspension 266 mg, Bupivacaine HCl, Bupivacaine liposome injectable suspension 133 mg - Bunionectomy, Hallux Valgus | Phase 3 | Completed | Pacira Pharmaceuticals, Inc | 185 | 2022-02-15 | 2025-06-26 |
| Novel Non-opioid Post-surgical Pain Treatment in Females Carbidopa-Levodopa (100mg/25mg):, Naproxen - Acute Pain, Bunionectomy | Phase 2 | Withdrawn | Northwestern University | 2021-11-01 | 2024-03-18 | |
| Evaluate the Efficacy and Safety of ACP-044 for the Treatment of Acute Postoperative Pain Following Bunionectomy ACP-044 Dose A, ACP-044 Dose B, Placebo - Acute Postoperative Pain, Bunionectomy | Phase 2 | Completed | ACADIA Pharmaceuticals Inc. | 239 | 2021-03-29 | 2023-05-03 |
| Safety and Performance of PEEK Anchors in Extremities Spyromite, Dynomite, Raptomite, Footprint Ultra PK SL - Medial or Lateral Instability Repairs/Reconstructions, Hallux Valgus Repairs | Completed | Smith & Nephew, Inc. | 140 | 2019-03-12 | 2024-10-01 | |
| A Trial to Evaluate CG5503 Efficacy and Safety in Acute Pain After Bunionectomy CG5503 IR, Morphine, Placebo - Bunionectomy, Pain | Phase 3 | Completed | Grünenthal GmbH | 291 | 2007-09-01 | 2011-11-16 |
| Study of Lornoxicam or Ketorolac or Placebo for Post-Operative Pain After Bunionectomy Lornoxicam 8 mg, Lornoxicam 16 mg, Ketorolac 30 mg - Bunionectomy, Orthopedic Surgery | Phase 2 | Completed | POZEN | 100 | 2005-11-01 | 2012-12-03 |
| A Study of AQUAVAN® Injection in the Presence of Pre-Medication in Patients Undergoing Minor Surgical Procedures fospropofol disodium - Arthroscopy, Bunionectomy | Phase 3 | Terminated | Eisai Inc. | 168 | 2004-10-01 | 2015-01-09 |
Acute Pain (3) · Agnosia (2) · Hallux Valgus (2) · Pain, Postoperative (2) · Bunion (1) · Median Neuropathy (1) · Pain (1)
Neurologic Manifestations (6) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Foot Deformities (3) · Musculoskeletal Diseases (3) · Nervous System Diseases (3) · Pain (3) · Neurobehavioral Manifestations (2) · Pathologic Processes (2) · Perceptual Disorders (2) · Postoperative Complications (2) · Foot Deformities, Acquired (1) · Mononeuropathies (1) · Neuromuscular Diseases (1) · Peripheral Nervous System Diseases (1)
Bupivacaine (2) · Acetaminophen (1) · Drug Evaluation (1) · Hydrocodone (1) · Inosine Monophosphate (1) · Ketorolac (1) · Morphine (1) · Naproxen (1) · Sodium Chloride (1) · carbidopa, levodopa drug combination (1) · fospropofol (1) · lornoxicam (1)
Grünenthal GmbH (2) · ACADIA Pharmaceuticals Inc. (1) · AmacaThera Inc. (1) · Eisai Inc. (1) · Northwestern University (1) · POZEN (1) · Pacira Pharmaceuticals, Inc (1) · Rebel Medicine Inc (1) · Smith & Nephew, Inc. (1)
United States (7) · Canada (1)
Gary Nevins (1) · James Jones, MD, PharmD (1) · Jayant Agarwal, MD (1) · Judth Horner (1) · Michael P. DeMicco, MD (1) · Stephen E Daniels, DO (1)