16 recruiting, 6 completed, 4 unknown, 3 not yet recruiting. 23 Not applicable, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 23 | Recruiting 13, Completed 3, Unknown 3, Not yet recruiting 2, Active not recruiting 1, Withdrawn 1 |
| Phase 2 | 3 | Recruiting 2, Completed 1 |
Follow Brain Stem Infarctions: new trials by email Literature Review of Brain Stem Infarctions trials Research Report on Brain Stem Infarctions
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT) INTENT Neural Interface System - Tetraplegia/Tetraparesis, Amyotrophic Lateral Sclerosis (ALS) | Not applicable | Recruiting | Johns Hopkins University | 5 | 2027-01-01 | 2026-10-09 |
| iBCI Optimization for Veterans With Paralysis Mobile neural decoding platform (mobile iBCI) - Spinal Cord Injury, Amyotrophic Lateral Sclerosis | Not applicable | Not yet recruiting | VA Office of Research and Development | 2 | 2026-10-02 | 2026-07-27 |
| Epidiolex Trial for Presymptomatic Treatment of Sturge-Weber Syndrome Epidiolex 100 mg/mL Oral Solution - Sturge - Weber Syndrome (SWS) | Phase 2 | Recruiting | Johns Hopkins University | 10 | 2026-09-17 | 2026-10-02 |
| Large Language Models Versus Anesthesiologists for ASA Physical Status Classification Anesthesia, Preoperative Risk Prediction | Not yet recruiting | Marmara University Pendik Training and Research Hospital | 350 | 2026-07-21 | 2026-07-10 | |
| Developing a Tailored Neuropsychological Rehabilitation for Sturge-Weber Syndrome Sturge - Weber Syndrome (SWS) | Recruiting | University of Roma La Sapienza | 40 | 2026-06-10 | 2026-06-17 | |
| MindEx: A Novel, Multifocal, Cognitive Brain-Machine Interface System Mind Extender (MindEx) - Paralysis; Quadriplegic, Quadraplegia | Not applicable | Recruiting | Nader Pouratian | 2 | 2026-02-20 | 2026-10-30 |
| RAINBOW-ICH Trial of AI Guided Minimally Invasive Neurosurgery for ICH AI-assisted robotic-guided endoscopic hematoma evacuation, Conventional craniotomy, AI-assisted robotic-guided puncture and hematoma evacuation - Basal Ganglia Hemorrhage, Intraventricular Hemorrhage | Not applicable | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 1000 | 2025-09-30 | 2026-01-08 |
| GB-PRIME: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices N1 Implant, R1 Robot - Tetraplegia/Tetraparesis, Quadriplegia | Not applicable | Recruiting | Neuralink Corp | 7 | 2025-07-31 | 2025-08-17 |
| UAE-PRIME: A Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices N1 Implant, R1 Robot - Tetraplegia/Tetraparesis, Quadriplegia | Not applicable | Recruiting | Neuralink Corp | 10 | 2025-05-09 | 2025-06-05 |
| A Study on the Safety and Functionality of the Implantable Wireless Brain-Computer Interfaces for Motor Rehabilitation Implant - Quadriplegia, Amputations | Not applicable | Not yet recruiting | Shanghai StairMed Technology Co., Ltd. | 5 | 2025-04-01 | 2025-04-25 |
| Research on Wireless Brain Implant System for General Control of External Devices WRS - Complete or Incomplete Paraplegia/quadriplegia, Spinal Cord Injury | Not applicable | Recruiting | Shanghai StairMed Technology Co., Ltd. | 4 | 2025-03-01 | 2025-03-13 |
| Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01) BrainGate Neural Interface System - Brainstem Stroke, ALS | Not applicable | Recruiting | Leigh R. Hochberg, MD, PhD. | 6 | 2024-07-22 | 2026-10-26 |
| Virtual Reality Therapy on Dysphagia in Wallenberg Syndrome Virtual Reality Therapy, Conventional dysphagia treatment - Wallenberg Syndrome | Not applicable | Unknown | Copka Sonpashan | 80 | 2024-03-01 | 2024-03-25 |
| Effect of Virtual Reality Therapy on Dysphagia in Wallenberg Syndrome Virtual Reality Therapy, Conventional dysphagia treatment - Wallenberg Syndrome | Not applicable | Unknown | Zeng Changhao | 80 | 2024-02-28 | 2024-03-06 |
| Hemorrhagic Brainstem Cavernous Malformations Treatment With Sirolimus: aSingle Centre, Randomized, Placebo-controlled Pilot Trial Sirolimus, Starch flake - Cavernous Malformations, Intracerebral Hemorrhage | Phase 2 | Recruiting | Huashan Hospital | 75 | 2024-01-05 | 2024-12-20 |
| Investigation on the Cortical Communication System ECoG (electrocorticography) sensing - Locked-in Syndrome, Neuromuscular Diseases | Not applicable | Recruiting | UMC Utrecht | 2 | 2023-12-15 | 2025-10-03 |
| Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia BrainGate Neural Interface System - Anarthria, Dysarthria | Not applicable | Recruiting | Leigh R. Hochberg, MD, PhD. | 3 | 2023-10-18 | 2026-06-02 |
| Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02) BrainGate Neural Interface System - Anarthria, Dysarthria | Not applicable | Recruiting | Leigh R. Hochberg, MD, PhD. | 2 | 2023-10-16 | 2025-12-01 |
| Cortical Function Changes During Swallowing in Patients With Dysphagia in Lateral Medullary Syndrome Functional near-infrared spectroscopy (fNIRS) detection - Deglutition Disorders, Lateral Medullary Syndrome | Unknown | The First Affiliated Hospital of Zhengzhou University | 20 | 2023-05-31 | 2024-01-19 | |
| The Motor Imagery Based on Action Observation Treatment on Dysphagia in Wallenberg Syndrome conventional dysphagia treatment, motor imagery based on action observation treatment - Lateral Medullary Syndrome, Deglutition Disorders | Not applicable | Completed | Le Wang | 30 | 2023-05-30 | 2024-01-25 |
Showing 20 of 31. Sign in to see all of them.
Spinal Cord Injuries (16) · Amyotrophic Lateral Sclerosis (15) · Quadriplegia (14) · Muscular Dystrophies (9) · Locked-In Syndrome (7) · Paralysis (5) · Lateral Medullary Syndrome (4) · Deglutition Disorders (3) · Muscular Atrophy, Spinal (3) · Stroke (3) · Brain Injuries, Traumatic (2) · Dysarthria (2) · Motor Neuron Disease (2) · Nervous System Diseases (2)
Brain Diseases (31) · Brain Infarction (31) · Brain Ischemia (31) · Cardiovascular Diseases (31) · Central Nervous System Diseases (31) · Cerebrovascular Disorders (31) · Infarction (31) · Ischemia (31) · Necrosis (31) · Pathologic Processes (31) · Pathological Conditions, Signs and Symptoms (31) · Vascular Diseases (31) · Nervous System Diseases (29) · Stroke (28) · Neurologic Manifestations (19)
Brain-Computer Interfaces (4) · Neural Prostheses (2) · Sirolimus (2) · Botulinum Toxins, Type A (1) · Cannabidiol (1) · Electrocorticography (1) · Injections (1) · Microelectrodes (1) · Mutagenesis, Insertional (1) · Solutions (1) · Therapeutics (1)
Leigh R. Hochberg, MD, PhD. (4) · Johns Hopkins University (3) · Neuralink Corp (2) · Shanghai StairMed Technology Co., Ltd. (2) · Synchron Medical, Inc. (2) · The First Affiliated Hospital of Zhengzhou University (2) · University of Pittsburgh (2) · Clinica Universidad de Navarra, Universidad de Navarra (1) · Copka Sonpashan (1) · Huashan Hospital (1) · Le Wang (1) · Marmara University Pendik Training and Research Hospital (1) · Michael Boninger (1) · Nader Pouratian (1) · Oregon Health and Science University (1)
United States (15) · China (7) · Australia (1) · Italy (1) · Netherlands (1) · Spain (1) · Taiwan (1) · United Arab Emirates (1) · United Kingdom (1)
Florian Roser, MD (1) · Jaimie Henderson, MD (1) · Jennifer L Collinger, PhD (1) · John D Simeral, PhD (1) · John S Nelson, M.D,PhD (1) · Katya Hill, PhD (1) · Laura Piccardi, PhD (1) · Leigh R Hochberg, M.D., Ph.D. (1) · Leigh R Hochberg, MD, Ph.D. (1) · Leyre Aguado, MD PhD (1) · Maider Pretel, MD PhD (1) · Melanie Fried-Oken, PhD (1) · Michael L Boninger, MD (1) · Nathan Crone, MD (1)
PMID 21436513, PMID 22596161, PMID 23838067, PMID 25385765, PMID 26413781, PMID 26987662, PMID 27900953, PMID 28220753, PMID 28278476, PMID 28363483, PMID 29160240, PMID 29209023, PMID 29363625, PMID 29553484, PMID 30429772, PMID 32494819, PMID 34847547, PMID 36639237, PMID 37425721, PMID 37841873, PMID 38579696, PMID 38671062, PMID 38925110, PMID 39141853, PMID 39371161, PMID 39433597, PMID 39720868, PMID 39793200, PMID 39808922, PMID 39883960, PMID 40106898, PMID 40280150, PMID 40506548, PMID 40570636, PMID 40832410, PMID 40972658, PMID 41040697, PMID 41256173, PMID 41928799, PMID 42750660
U01DC017844 (2), 1DP2DC021055 (1), I01RX003803 (1), R01DC009899 (1), R01DC014034 (1), U01DC019430 (1), U01NS123101 (1), UH2NS095548 (1), UH3NS114439 (1)