Bone Loss: Clinical Trials

184 trials for Bone Loss, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

92 completed, 42 unknown, 22 recruiting, 8 terminated. 104 Not applicable, 16 Phase 2, 14 Phase 4, 9 Phase 3, 4 Phase 1.

By phase and status

PhaseTrialsStatus
Not applicable104Completed 56, Unknown 24, Recruiting 10, Not yet recruiting 4, Terminated 4, Active not recruiting 3, Withdrawn 2, Suspended 1
Phase 216Completed 11, Terminated 2, Unknown 2, Not yet recruiting 1
Phase 414Completed 9, Unknown 2, Active not recruiting 1, Not yet recruiting 1, Recruiting 1
Phase 39Completed 5, Enrolling by invitation 1, Recruiting 1, Terminated 1, Withdrawn 1
Phase 14Completed 2, Terminated 1, Unknown 1
Early Phase 12Completed 1, Unknown 1

Follow Bone Loss: new trials by email Literature Review of Bone Loss trials Research Report on Bone Loss

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Melatonin in Posterior Mandible Extraction Socket
Melatonin group, Placebo group - Bone Loss
Phase 2Not yet recruitingCairo University402026-11-152026-11-06
Comparison of Induced Membrane Technique With Vascularized Fibula Flap for Pediatric Limb Reconstruction
limb reconstruction - Bone Loss, Microsurgery
Not yet recruitingCentral Hospital, Nancy, France1402026-09-152026-09-17
Release Kinetics of rhBMP-2 Using E-PRF as an Autologous Carrier: An In Vitro Analysis
E-PRF/rhBMP-2 (similar ratios), E-PRF/ACS/rhBMP-2, rhBMP-2/E-PRF - Bone Loss
WithdrawnUniversity of Alabama at Birmingham2026-09-012026-09-30
Influence of Acetal Resin Versus Nylon Elastic Cap on Crestal Bone Loss in Mandibular Implant-Supported Overdenture
Acetal Resin, nylon - Bone Loss, Pocket, Periodontal
Not applicableNot yet recruitingFuture University in Egypt222026-07-012026-06-24
Evaluation of the Safety, Feasibility, and Early Clinical Outcomes of Patient-Specific Bone Defect Implants Fabricated From Titanium Alloy (Ti-6Al-4V) Using 3D Printing Technology
Patient-specific 3D-printed Ti-6Al-4V bone implant - Bone Loss, Bone Defects
Not applicableNot yet recruitingVinUniversity102026-04-012026-04-20
Comparison of Bone Microarchitecture Analysed by HRpQCT and pQCT in Pathologies With Bone Loss and/or Muscle Loss
HR-pQCT, pQCT, DEXA - Osteoporosis Risk, Bone Loss
Not applicableRecruitingCentre Hospitalier Universitaire de Saint Etienne10002026-02-022026-03-03
Crestal Bone Response to Narrow vs. Regular Tie-Base in Subcrestal Implants
Intervention Name (Arm 1): Narrow tie-base abutment Intervention Name (Arm 2): Regular tie-base abutment - Bone Loss
Not applicableNot yet recruitingMenoufia University402025-09-302025-09-29
Bone Response to Exercise and Energy Restriction in Young Adults
Energy restriction - Bone Resorption, Bone Loss
Not applicableSuspendedBrock University122025-09-302024-12-31
Prosthetic Modality and MBL
Traditional prosthetic procedure, one abutment-one time - Bone Loss
Not applicableRecruitingStudio Odontoiatrico Associato Dr. P. Cicchese e L. Canullo602025-09-012025-09-04
Prospective Outcomes of Guided Equator Overdentures
Fully guided static computer-assisted implant surgery (CAIS) for mandibular overdentures using Equator® attachments - Bone Loss
RecruitingMenoufia University402025-09-012025-09-29
Osteogenic Action of a Medical Device Based on Beta-tricalcium Phosphate (BTCP)
Medical device: beta-tricalcium phosphate, Bovine Hydroxyapatite - Bone Loss, Regenerative Inflammation
Phase 4Not yet recruitingMario Pérez Sayáns302025-07-012025-04-24
Study on Safety and Performance of AdvanCore Bone Void Filler
AdvanCore bone grafting - Bone Fractures, Bone Defects
Not applicableRecruitingArtur Salgado SA1902025-05-292025-05-31
Evaluation of the Osteoinductivity of Atorvastatin Combined With β-TCP
Cyst enucleation and bone grafting - Infection, Bone Loss
Not applicableUnknownCairo University102024-12-012024-08-13
Radiographic Assessment Of The Accuracy Of 3D Ridge Augmentation In Anterior Mandible Using Computer Guided Autogenous Cortical Shell Technique Versus Free Hand Technique
horizontal and vertical bone augmentation using computer guided cortical shell technique, free hand cortical shell technique in anterior 3d defect - Bone Loss
Not applicableNot yet recruitingCairo University222024-11-212024-11-15
Artificial Intelligence-Enhanced Three-Dimensional Reconstruction of Ridge Deficiencies
AI/guided block graft, AI/guided shell graft - Bone Loss
Not applicableCompletedKafrelsheikh University222024-11-172026-01-12
Impact of Transepithelial Abutment Connection and Disconnection in Dental Implants
abutment placement, Ti-base placement - Bone Loss, Bacterium; Agent
Not applicableCompletedUniversity of Valencia322024-11-012026-07-13
Innovative Technologies for Salvage Procedures of Failed Treatments of Osteoarthritis: Biomimetics Solutions (CustomPN)
custom-made acetabular implant - Bone Loss, Hip Prosthesis Infection
RecruitingIstituto Ortopedico Rizzoli152024-10-012026-02-23
Bone in CKD Alkali Response (BICARb Pilot Trial)
Potassium Citrate Extended Release Oral Tablet, Placebo, Potassium Citrate and Citric Acid Oral Solution - Chronic Kidney Diseases, Bone Loss
Phase 2 / Phase 3TerminatedAlbert Einstein College of Medicine62024-08-152026-07-28
An International, Multicenter, Prospective Registry on Post-traumatic Long Bones Defects
Any treatment that is used for a defect of any long bone - Limb Fracture, Bone Loss
RecruitingAO Innovation Translation Center6002024-07-032025-08-29
Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration
PCL Scaffold, PTFE + Bio-Oss® - Bone Loss, Jaw, Edentulous
Phase 3Enrolling by invitationUniversidad Austral de Chile102024-07-012025-01-15

Showing 20 of 184. Sign in to see all of them.

Narrower conditions

Bone Diseases, Metabolic (184)  ·  Osteoporosis (30)  ·  Fractures, Bone (11)  ·  Bone Resorption (9)  ·  Spinal Cord Injuries (8)  ·  Feeding and Eating Disorders (5)  ·  Motor Activity (5)  ·  Muscular Atrophy (5)  ·  Obesity (5)  ·  Weight Loss (5)  ·  Bone Diseases (4)  ·  Musculoskeletal Diseases (4)  ·  Patient Satisfaction (4)  ·  Peri-Implantitis (4)  ·  Spinal Cord Diseases (4)

Broader conditions

Metabolic Diseases (184)  ·  Nutritional and Metabolic Diseases (183)  ·  Bone Diseases (180)  ·  Musculoskeletal Diseases (180)  ·  Pathological Conditions, Signs and Symptoms (34)  ·  Signs and Symptoms (26)  ·  Wounds and Injuries (21)  ·  Stomatognathic Diseases (18)  ·  Mouth Diseases (15)  ·  Nervous System Diseases (15)  ·  Behavior (14)  ·  Body Weight (13)  ·  Periodontal Diseases (13)  ·  Pathologic Processes (11)  ·  Trauma, Nervous System (9)

Interventions

Zoledronic Acid (12)  ·  Dental Implants (5)  ·  Risedronic Acid (5)  ·  Calcium (4)  ·  Exercise (4)  ·  Teriparatide (4)  ·  Vitamin D (4)  ·  Alendronate (3)  ·  Cholecalciferol (3)  ·  Denosumab (3)  ·  Sodium Chloride (3)  ·  Absorptiometry, Photon (2)  ·  Bone Transplantation (2)  ·  Diphosphonates (2)  ·  Durapatite (2)

Sponsors

Cairo University (12)  ·  Menoufia University (8)  ·  Mansoura University (7)  ·  Massachusetts General Hospital (4)  ·  Northwestern University (4)  ·  Wake Forest University Health Sciences (4)  ·  Implantology Institute (3)  ·  Thomas J. Schnitzer (3)  ·  University of Alabama at Birmingham (3)  ·  Ain Shams University (2)  ·  Alexandria University (2)  ·  Assiut University (2)  ·  Brock University (2)  ·  Centre Hospitalier Universitaire de Saint Etienne (2)  ·  Future University in Egypt (2)

Countries

United States (42)  ·  Egypt (34)  ·  Spain (13)  ·  Italy (11)  ·  Canada (9)  ·  France (6)  ·  Brazil (5)  ·  China (5)  ·  Portugal (5)  ·  Turkey (Türkiye) (5)  ·  United Kingdom (5)  ·  Denmark (4)  ·  Germany (4)  ·  Poland (4)  ·  Australia (3)

Top investigators

Thomas J Schnitzer, MD, PhD (6)  ·  Elena Cervino, Msc (3)  ·  Khloud Ezzat, PhD (3)  ·  Mohammed El-Sawy, PhD (3)  ·  Andre Chen, Msc (2)  ·  Helena Francisco, Msc (2)  ·  Mohammed A. El-Sawy, PhD (2)  ·  Rehab F Ghouraba, PHD (2)  ·  Alexey Y. Drobyshev, MD,PhD,Prof. (1)  ·  Amos Yahav, DMD (1)  ·  Andre Chen, Phd (1)

Results publications

PMID 30334093, PMID 38979716, PMID 16195252, PMID 18705811, PMID 19393473, PMID 20950166, PMID 21555774, PMID 22136751, PMID 23047045, PMID 23739654, PMID 23965841, PMID 24166063, PMID 24284444, PMID 24641883, PMID 24923792, PMID 25479571, PMID 25867538, PMID 26828618, PMID 27193748, PMID 28803675, PMID 29262027, PMID 29963602, PMID 30931746, PMID 31480877, PMID 31621838, PMID 32032406, PMID 32066431, PMID 32154945, PMID 32831908, PMID 33017060, PMID 33103032, PMID 33471238, PMID 34278611, PMID 34547072, PMID 34818393, PMID 34887285, PMID 36209245, PMID 36383511, PMID 36997448, PMID 37675989, PMID 37777776, PMID 38688489, PMID 38694811, PMID 39053878, PMID 39112988, PMID 39350107, PMID 39665575, PMID 39909519, PMID 39950686, PMID 40162303

NIH funding

2023 (1), K25AG058804 (1), R01AG028086 (1), R01AG074979 (1), R01CA122658 (1), R01DK131811 (1), U01AR080969 (1)