5 completed, 1 enrolling by invitation, 1 recruiting, 1 terminated. 9 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 9 | Completed 5, Enrolling by invitation 1, Recruiting 1, Terminated 1, Withdrawn 1 |
| Phase 2 | 1 | Terminated 1 |
Follow Bone Loss: new trials by email Literature Review of Bone Loss trials Research Report on Bone Loss
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bone in CKD Alkali Response (BICARb Pilot Trial) Potassium Citrate Extended Release Oral Tablet, Placebo, Potassium Citrate and Citric Acid Oral Solution - Chronic Kidney Diseases, Bone Loss | Phase 2 / Phase 3 | Terminated | Albert Einstein College of Medicine | 6 | 2024-08-15 | 2026-07-28 |
| Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration PCL Scaffold, PTFE + Bio-Oss® - Bone Loss, Jaw, Edentulous | Phase 3 | Enrolling by invitation | Universidad Austral de Chile | 10 | 2024-07-01 | 2025-01-15 |
| Socket Preservation Using Dentin Graft Autogenous Dentin Graft With Collagen Sponge on Dental Implant Stability AUTOGENOUS TOOTH GRAFT WITH COLLAGEN SPONGE ON DENTAL IMPLANT STABILITY Demineralized freeze dried allograft with collagen sponge, autogenous dentin graft with collagen sponge - Bone Loss, Bone Remodeling Disorder | Phase 3 | Completed | Faculty of Dental Medicine for Girls | 16 | 2023-09-15 | 2025-03-03 |
| Bisphosphonate Use to Mitigate Bone Loss Secondary to Bariatric Surgery Risedronate, Placebo - Bone Loss | Phase 3 | Recruiting | Wake Forest University Health Sciences | 200 | 2023-03-28 | 2026-02-19 |
| Effects of Romosozumab on Bone Density in Women With Anorexia Nervosa Romosozumab Prefilled Syringe, Placebo, Zoledronic acid 5 mg - Bone Density, Low, Bone Loss | Phase 3 | Completed | Karen Klahr Miller, MD | 30 | 2021-09-20 | 2025-12-16 |
| Simplified vs Conventional Drilling Protocol for Implant Placment Conventional, simplfied - MBL, Bone Loss | Phase 3 | Completed | Universidad Católica San Antonio de Murcia | 46 | 2020-12-01 | 2025-01-17 |
| Effects of Denosumab on Bone Mineral Density in Women With Anorexia Nervosa: A Pilot Study Denosumab 60 MG [Prolia], Placebo Injection, Alendronate 70Mg Tab - Bone Density, Bone Loss | Phase 3 | Completed | Massachusetts General Hospital | 30 | 2017-10-25 | 2025-11-04 |
| Bone Mass Accrual in Adolescent Athletes Estrogen - Amenorrhea, Bone Loss | Phase 3 | Withdrawn | Massachusetts General Hospital | 2008-12-01 | 2021-10-26 | |
| Zoledronic Acid in the Prevention of Cancer Treatment Related Bone Loss in Postmenopausal Women Receiving Letrozole for Breast Cancer. Zoledronic acid, Letrozole - Bone Loss, Breast Cancer | Phase 3 | Completed | Novartis Pharmaceuticals | 1065 | 2003-05-01 | 2012-04-16 |
Bone Diseases, Metabolic (9) · Anorexia Nervosa (2) · Feeding and Eating Disorders (2) · Acidosis (1) · Amenorrhea (1) · Bone Resorption (1) · Breast Neoplasms (1) · Fractures, Bone (1) · Jaw Fractures (1) · Jaw, Edentulous (1) · Mouth, Edentulous (1) · Osteoporosis (1) · Renal Insufficiency, Chronic (1)
Bone Diseases (9) · Metabolic Diseases (9) · Musculoskeletal Diseases (9) · Nutritional and Metabolic Diseases (9) · Pathological Conditions, Signs and Symptoms (4) · Mental Disorders (2) · Pathologic Processes (2) · Signs and Symptoms (2) · Signs and Symptoms, Digestive (2) · Wounds and Injuries (2) · Acid-Base Imbalance (1) · Breast Diseases (1) · Chronic Disease (1) · Craniocerebral Trauma (1) · Disease Attributes (1)
Zoledronic Acid (2) · Alendronate (1) · Citric Acid (1) · Congresses as Topic (1) · Denosumab (1) · Estradiol (1) · Estrogens (1) · Letrozole (1) · Potassium Citrate (1) · Progesterone (1) · Risedronic Acid (1)
Massachusetts General Hospital (2) · Albert Einstein College of Medicine (1) · Faculty of Dental Medicine for Girls (1) · Karen Klahr Miller, MD (1) · Novartis Pharmaceuticals (1) · Universidad Austral de Chile (1) · Universidad Católica San Antonio de Murcia (1) · Wake Forest University Health Sciences (1)
United States (5) · Chile (2) · Egypt (2) · Spain (2) · Argentina (1) · Australia (1) · Belgium (1) · Brazil (1) · China (1) · Colombia (1) · Czechia (1) · Finland (1) · France (1) · Germany (1) · Guatemala (1)
Jamy Ard, MD (1) · Karen K Miller, MD (1) · Kimberly Reidy, MD (1) · Kristen Beavers, PhD, MPH, RD (1) · Madhu Misra, MD, MPH (1)
PMID 23047045, PMID 38979716, PMID 39665575
2023 (1), R01DK131811 (1), U01AR080969 (1)