33 completed, 8 recruiting, 6 not yet recruiting, 4 unknown. 19 Not applicable, 4 Phase 2, 3 Phase 3, 1 Phase 1.
Follow Barotrauma: new trials by email Literature Review of Barotrauma trials Research Report on Barotrauma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Blast-related Regional Anaesthesia and Peripheral nerVe Injury Evaluation Standardized Multimodal Analgesia, Ultrasound-Guided Regional Anaesthesia - Nerve Block, Nerve Blocks | Not applicable | Not yet recruiting | Ukrainian Society of Regional Anesthesia and Pain Therapy | 150 | 2026-12-23 | 2026-10-19 |
| Health, Fitness, and Safety Knowledge as Determinants of Adverse Events in Recreational Divers in Poland Anonymous online questionnaire - Decompression Sickness, Barotrauma | Not yet recruiting | Medical University of Bialystok | 384 | 2026-10-01 | 2026-10-02 | |
| NASA Exercise Prebreathe Study Oxygen Prebreathe and Hypobaric Exposure - Decompression Sickness | Not applicable | Recruiting | Duke University | 30 | 2026-08-13 | 2026-10-05 |
| Biomarkers of Brain Health in Blast Overpressure Exposure Blast overpressure exposure during explosive breaching training - Blast Overpressure Exposure, Blast Injuries | Completed | Neurable, Inc | 12 | 2026-08-10 | 2026-09-10 | |
| Post-Amputation Stump Infection as a Predictor of Persistent Residual Limb Pain: A Prospective Cohort Study Residual Limb Pain, Stump Pain | Not yet recruiting | Ukrainian Society of Regional Anesthesia and Pain Therapy | 150 | 2026-06-23 | 2026-06-03 | |
| Ultrasound Predictors of Persistent Burn Scar Pain After Blast and Drone-Related Injuries: A Prospective Cohort Study Burn Scar Pain, Neuropathic Pain | Not yet recruiting | Ukrainian Society of Regional Anesthesia and Pain Therapy | 150 | 2026-03-24 | 2026-02-27 | |
| Chronic Pain After Combat-Related Traumatic Brain Injury (cTBI-Pain Study) A Prospective Cohort Study of Pain Chronification After Combat-Related Traumatic Brain Injury Pain, Chronic Pain | Not yet recruiting | Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans) | 100 | 2026-02-15 | 2026-02-24 | |
| Precision Biomarkers to Detect Brain Injury in Active-Duty United States Special Operations Forces With Repeated Blast Exposure PBR28 TSPO PET - Blast Injury | Phase 2 | Recruiting | Massachusetts General Hospital | 100 | 2025-10-14 | 2025-10-31 |
| Rhu-pGSN to Mitigate Proinflammatory Responses to Decompression in Healthy SCUBA Divers Sodium Chloride 0.9% Inj pre-exposure, Sodium Chloride 0.9% Inj post-exposure, Recombinant human plasma gelsolin pre-exposure - Decompression Sickness | Phase 2 | Completed | BioAegis Therapeutics Inc. | 36 | 2025-08-15 | 2026-10-02 |
| NASA Prebreathe Study Altitude, 100% Oxygen - Decompression Sickness | Phase 1 | Completed | Duke University | 19 | 2025-05-05 | 2026-06-01 |
| Epidemiological Assessment of Technical Diving Accidents in Mainland France and Factors Predictive of Severity (TEKCare) Decompression Sickness, Pulmonary Edema - Acute | Unknown | University Hospital, Brest | 100 | 2025-01-01 | 2024-10-04 | |
| Prediction & Mechanisms of Recovery Following IEDS Decompression Sickness | Not yet recruiting | University of Plymouth | 41 | 2024-06-01 | 2024-05-13 | |
| Comparing Hearing Aid Fitting Methods in Blast-exposed Veterans Phonak Lumina P90 - Auditory Diseases, Central | Not applicable | Recruiting | VA Office of Research and Development | 80 | 2024-04-01 | 2026-04-14 |
| Fireworks Eye Injuries During Festivals in Upper Egypt fireworks eye injury - Ocular Injury, Blast Injuries | Completed | Assiut University | 59 | 2024-04-01 | 2026-05-18 | |
| Laboratory Biomarkers and Pulmonary Interstitial Emphysema in ARDS (PIE-ARDS) Blood and bronchoalveolar fluid collection and analysis, Chest CT scan - Acute Respiratory Distress Syndrome, Barotrauma | Recruiting | Università Vita-Salute San Raffaele | 110 | 2023-11-27 | 2025-08-12 | |
| Imaging Biomarkers to Stratify the Risk of Barotrauma in ARDS Chest Computed Tomography Scan per normal clinical practice - Acute Respiratory Distress Syndrome, Barotrauma | Recruiting | Università Vita-Salute San Raffaele | 100 | 2023-08-30 | 2025-08-06 | |
| Effectiveness of Sequential Eustachian Tube Maneuvers in Hyperbaric Oxygen Conditions Maneuver group - Barotrauma;Ear, Tympanum; Perforation | Not applicable | Recruiting | Hospital Felicio Rocho | 100 | 2023-05-01 | 2026-02-09 |
| Diagnostic Precision and Accuracy Using the Teed Scoring System Versus the O'Neill Grading System Otic Barotrauma Grading System - Otic Barotrauma, Pressure Injury | Enrolling by invitation | Northwell Health | 30 | 2023-02-01 | 2026-06-10 | |
| Barotrauma in Hyperbaric Oxygen Therapy Pseudoephedrine Pill, Placebo - Barotrauma | Not applicable | Recruiting | John Muir Health | 90 | 2023-01-31 | 2025-08-27 |
| Impact of Hyperoxia and Involvement of the Immune System in Diving Accident Hyperbaric oxygen therapy, Diving simulation - Decompression Sickness | Not applicable | Recruiting | Direction Centrale du Service de Santé des Armées | 265 | 2022-03-30 | 2023-04-28 |
Showing 20 of 55. Sign in to see all of them.
Blast Injuries (22) · Decompression Sickness (20) · Brain Injuries, Traumatic (7) · Inflammation (4) · Brain Concussion (3) · COVID-19 (3) · Neuralgia (3) · Stress Disorders, Post-Traumatic (3) · Brain Injuries (2) · Chronic Pain (2) · Foramen Ovale, Patent (2) · Hearing Loss (2) · Motor Activity (2) · Multiple Trauma (2)
Wounds and Injuries (53) · Nervous System Diseases (16) · Pathological Conditions, Signs and Symptoms (12) · Trauma, Nervous System (11) · Brain Diseases (10) · Central Nervous System Diseases (10) · Craniocerebral Trauma (10) · Respiratory Tract Diseases (9) · Lung Diseases (8) · Brain Injuries (7) · Infections (7) · Mental Disorders (7) · Neurologic Manifestations (7) · Signs and Symptoms (7)
Oxygen (2) · Sodium Chloride (2) · 4-Aminopyridine (1) · Air (1) · Altitude (1) · Blood Specimen Collection (1) · Cognitive Training (1) · High-Intensity Interval Training (1) · Hyperbaric Oxygenation (1) · Noninvasive Ventilation (1) · Pressure (1) · Pseudoephedrine (1) · Saline Solution (1) · Transcranial Magnetic Stimulation (1)
Duke University (3) · Karolinska Institutet (3) · Sahlgrenska University Hospital (3) · Ukrainian Society of Regional Anesthesia and Pain Therapy (3) · VA Office of Research and Development (3) · Massachusetts General Hospital (2) · US Department of Veterans Affairs (2) · University Hospital, Brest (2) · University of Split (2) · Università Vita-Salute San Raffaele (2) · Assiut University (1) · BioAegis Therapeutics Inc. (1) · Boston Medical Center (1) · Center for Veterans Research and Education (1) · Centre Hospitalier Universitaire de Nice (1)
United States (24) · Sweden (6) · France (3) · Italy (3) · Canada (2) · Croatia (2) · Ukraine (2) · Austria (1) · Brazil (1) · Czechia (1) · Egypt (1) · Iraq (1) · Jordan (1) · Mexico (1) · Oman (1)
Henrik Zetterberg, PhD (3) · Alicia Howell-Munson, PhD (1) · Amy O. Bowles, MD (1) · Blessen C Eapen, MD (1) · Brian L Edlow, M.D. (1) · Cuneyt M Alper, MD (1) · Daniel Krawcyzk, Ph.D. (1) · David Dayya, DO, PhD, MPH (1) · Doug B Cooper, PhD (1) · Elizabeth M. Hannold, PhD MS BS (1) · Frederick J Gallun, PhD (1) · Giovanni Landoni, Professor (1) · Jacinta Showers, RN (1) · Jakub Honek, MD (1) · John C Elfar, MD (1)
PMID 10898201, PMID 12046489, PMID 17099530, PMID 17414553, PMID 17543685, PMID 18646080, PMID 18808432, PMID 20084702, PMID 20358706, PMID 20955336, PMID 21316515, PMID 21712971, PMID 22767074, PMID 23363480, PMID 23999350, PMID 24630875, PMID 24875691, PMID 25287701, PMID 25860148, PMID 30357467, PMID 30478024, PMID 32087175, PMID 32975632, PMID 34515212, PMID 35144650, PMID 38970237, PMID 39936659, PMID 42233740, PMID 42430328, PMID 9188971, PMID 9356079
2009 (1), I01RX005059 (1), P50DC007667 (1), UL1RR025771 (1)