841 completed, 178 unknown, 107 recruiting, 71 terminated. 241 Not applicable, 240 Phase 3, 232 Phase 2, 132 Phase 1, 129 Phase 4.
Follow Mycoses: new trials by email Literature Review of Mycoses trials Research Report on Mycoses
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Echinocandin Added to Standard Treatment for Severe Pneumocystis Pneumonia Echinocandins, Placebo (0.9% Sodium chloride) infusion - Pneumocystis Jirovecii Pneumonia | Phase 3 | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 416 | 2027-04-01 | 2026-10-28 |
| Optimizing Care for Cryptococcal Antigenemia: Evaluation of Short Course Fluconazole and ART Timing Among CrAg+ Persons With Low Titers Immediate ART Initiation, Delayed ART Initiation, 10-Week Fluconazole - Cryptococcal Antigenemia, HIV-1-infection | Phase 3 | Not yet recruiting | University of Minnesota | 505 | 2027-01-05 | 2026-09-03 |
| Safety and Immunogenicity of VPM1002 Vaccination or BCG Revaccination Against TB in Pre-Adolescents Living With and Without HIV in South Africa VPM1002 Vaccine, BCG Vaccine, Placebo - Tuberculosis, HIV Infections | Phase 1 / Phase 2 | Withdrawn | International Maternal Pediatric Adolescent AIDS Clinical Trials Group | 2026-12-31 | 2026-08-17 | |
| Platform Trial for Salvage Consolidation Therapy in Dimorphic Fungi Oteseconazole - Coccidioidomycosis, Blastomycosis | Phase 2 | Not yet recruiting | University of Minnesota | 30 | 2026-12-01 | 2026-09-04 |
| A Phase II Randomized Study to Evaluate Measures for Endpoint Derivation in Patients With Progressive or Refractory Disseminated Coccidioidomycosis Treated With Olorofim Plus Baseline Standard of Care or Placebo Plus Baseline Standard of Care Olorofim, Placebo - Coccidioidomycosis, Disseminated Fungal Infection | Phase 2 | Not yet recruiting | F2G Ltd | 50 | 2026-12-01 | 2026-09-22 |
| Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis | Phase 4 | Not yet recruiting | Jay C. Buckey Jr. | 100 | 2026-11-01 | 2026-09-09 |
| Histoplasmosis Induction and Consolidation Therapy Factorial Randomized Clinical Trial (Histo-FACT) LAmB B, Posaconazole, World Health Organization (WHO)-recommended SOC - Histoplasmosis | Phase 3 | Not yet recruiting | University of Minnesota | 664 | 2026-11-01 | 2026-10-02 |
| A Study of Itraconazole and Posaconazole for Chronic Pulmonary Aspergillosis Posaconazole Delayed Release Oral Tablet, Itraconazole (ITZ) - Chronic Pulmonary Aspergillosis | Phase 3 | Not yet recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 220 | 2026-11-01 | 2026-10-01 |
| Real-World Effectiveness of Depemokimab in Allergic Bronchopulmonary Aspergillosis With Severe Eosinophilic Asthma Depemokimab - Allergic Bronchopulmonary Aspergillosis, ABPA | Not applicable | Not yet recruiting | Qianfoshan Hospital | 10 | 2026-11-01 | 2026-09-24 |
| Systemic Antifungal Plus Q-Switched Nd:YAG Laser for Onychomycosis Terbinafine, Q-switched Nd:YAG laser - Onychomycosis | Not applicable | Not yet recruiting | Assiut University | 97 | 2026-10-10 | 2026-10-09 |
| In Vitro Susceptibility of Dermatophytes to Terbinafine and Itraconazole: MIC Distributions and Elevated-MIC Isolates in Faisalabad, Pakistan In vitro antifungal susceptibility testing - Dermatophytosis, Tinea Corporis | Recruiting | Dr. Amara Safdar | 120 | 2026-10-02 | 2026-10-27 | |
| Comparison of Itraconazole With Itraconazole and Isotretinoin in the Treatment Duration, Safety a n d Cure Rate in Adult Patients of Tinea Corporis/ Cruris-A Randomised Controlled Trail Itraconazole (200 mg), ISOtretinoin 20 MG - Tinea Corporis | Phase 4 | Not yet recruiting | Pak Emirates Military Hospital | 60 | 2026-10-01 | 2026-06-30 |
| Clinical, Dermoscopic, and Mycological Evaluations of Resistant Dermatophytosis Direct microscopic KOH examination, Culture:, Antifungal susceptibility testing: - Fungal Skin Infection, Tinea Corporis | Not yet recruiting | Sohag University | 100 | 2026-10-01 | 2026-09-01 | |
| Assessment of the Risk of Zoonotic Infections in Prisons in French Guiana Q Fever, Leptospirosis | Not yet recruiting | Centre Hospitalier de Cayenne | 450 | 2026-10-01 | 2026-10-19 | |
| Cryptococcosis Associated With Bruton Tyrosine Kinase Inhibitors Cryptococcosis | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 30 | 2026-10-01 | 2026-10-19 | |
| Evaluation of Diagnostic Accuracy and Clinical Performance of the UllCORE Bloodstream Infection (BSI) Test UllCORE BSI Test - Blood Stream Infection, Blood Stream Infections | Recruiting | Deepull Diagnostics S.L. | 1500 | 2026-09-21 | 2026-10-08 | |
| Clinical, Dermoscopic, and Mycological Characteristics of Tinea Capitis in Children Dermoscopic examination: the findings are divided into pathognomic and non-specific signs, Direct Microscopy (KOH) examination, Fungal culture: - Fungal Infection by Site, Tinea Capitis | Not yet recruiting | Sohag University | 100 | 2026-09-20 | 2026-09-03 | |
| Real-World Effectiveness of Tezepelumab in Allergic Bronchopulmonary Aspergillosis Tezepelumab - Allergic Bronchopulmonary Aspergillosis, Severe Asthma | Not applicable | Not yet recruiting | Qianfoshan Hospital | 10 | 2026-09-01 | 2026-08-11 |
| Shortening Treatment Duration in Uncomplicated Candidemia: the CanTEN Trial Caspofungin only within the study, Caspofungin for 3 days within the study, Placebo only within the study - Candidemia, Invasive Candidiasis | Phase 4 | Not yet recruiting | Oliver Cornely, MD | 420 | 2026-09-01 | 2026-09-01 |
| mNGS for IFD in Patients With Hematological Malignancies metagenomic next-generation sequencing - Hematological Malignancies, Invasive Fungal Disease | Not yet recruiting | Nanfang Hospital, Southern Medical University | 50 | 2026-08-10 | 2026-08-13 |
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Invasive Fungal Infections (135) · Onychomycosis (135) · Candidiasis (132) · HIV Infections (128) · Acquired Immunodeficiency Syndrome (116) · Pneumonia, Pneumocystis (108) · Candidiasis, Vulvovaginal (107) · Aspergillosis (95) · Tinea Pedis (70) · Candidemia (69) · AIDS-Related Opportunistic Infections (64) · Candidiasis, Invasive (64) · Meningitis, Cryptococcal (54) · Candidiasis, Oral (48)
Bacterial Infections and Mycoses (1307) · Infections (1288) · Skin and Connective Tissue Diseases (309) · Skin Diseases (302) · Skin Diseases, Infectious (294) · Dermatomycoses (283) · Pathological Conditions, Signs and Symptoms (282) · Urogenital Diseases (272) · Genital Diseases (265) · Respiratory Tract Diseases (249) · Immune System Diseases (234) · Lung Diseases (233) · Candidiasis (214) · Tinea (213)
Fluconazole (108) · Voriconazole (65) · Itraconazole (56) · Caspofungin (52) · Amphotericin B (50) · Micafungin (46) · posaconazole (41) · liposomal amphotericin B (34) · Terbinafine (30) · Anidulafungin (24) · Trimethoprim, Sulfamethoxazole Drug Combination (24) · Pentamidine (22) · Clotrimazole (19) · Flucytosine (13) · Leucovorin (13)
National Institute of Allergy and Infectious Diseases (NIAID) (77) · Pfizer (71) · Merck Sharp & Dohme LLC (43) · Assiut University (19) · Astellas Pharma Inc (19) · Post Graduate Institute of Medical Education and Research, Chandigarh (16) · Scynexis, Inc. (14) · University of Pittsburgh (14) · Assistance Publique - Hôpitaux de Paris (13) · National Cancer Institute (NCI) (13) · Basilea Pharmaceutica (11) · Radboud University Medical Center (11) · Sun Pharmaceutical Industries, Inc. (11) · Merz North America, Inc. (9) · Qianfoshan Hospital (9)
United States (449) · France (128) · China (107) · Germany (67) · Canada (62) · Spain (60) · Italy (59) · Belgium (49) · India (48) · Netherlands (47) · Brazil (45) · United Kingdom (43) · South Korea (33) · Egypt (32) · Australia (26)
Marc Engelhardt (8) · David Angulo, MD (7) · Feinberg J (5) · Anya Loncaric (3) · Dieter Buchheidt, MD (3) · Eduardo Tschen, MD (3)
PMID 28459966, PMID 28597967, PMID 33891293, PMID 31280481, PMID 36396498, PMID 39972326, PMID 19506188, PMID 21147825, PMID 23315320, PMID 23959319, PMID 25007364, PMID 26969258, PMID 30325463, PMID 32843994, PMID 33027187, PMID 33438477, PMID 34988242, PMID 36255448, PMID 36988461, PMID 37185921, PMID 38008099, PMID 38319878, PMID 38502709, PMID 39010708, PMID 39468640, PMID 39529079, PMID 40970688, PMID 41151592, PMID 41940006, PMID 42446237, PMID 10233295, PMID 10394018, PMID 10394019, PMID 10642676, PMID 10747150, PMID 10782340, PMID 10832689, PMID 11285665, PMID 11520759, PMID 11561801, PMID 11687311, PMID 12131029, PMID 12145716, PMID 12386069, PMID 12515932, PMID 12572722, PMID 12729424, PMID 14723731, PMID 15232472, PMID 15355406
2008 (10), 2009 (8), 2017 (6), 2019 (6), 2015 (5), 2018 (4), 2023 (4), U10CA095861 (3), 2014 (2), 2016 (2), 5UL1RR024982-02 (2), P50HL084932 (2), U10EY018573 (2), UG1CA189955 (2), 2025 (1)