249 completed, 19 unknown, 11 not yet recruiting, 9 recruiting. 137 Phase 3, 57 Phase 4, 45 Phase 2, 26 Phase 1, 20 Not applicable.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PHASE 1 TRIAL OF Lm-LLO-TT AND GEMCITABINE IN UNRESECTABLE PANCREATIC DUCTAL ADENOCARCINOMA Lm-LLO-TT - Pancreas Cancer, Duct Cell Adenocarcinoma, Pancreatic Cancer | Phase 1 | Not yet recruiting | Loki Therapeutics, Inc. | 18 | 2026-10-15 | 2026-09-18 |
| Observation of Immune Persistence in a Clinical Trial of an Adsorbed Tetanus Vaccine Previously vaccinated with TTVA, Previously vaccinated with TT - Tetanus | Not yet recruiting | CanSino Biologics Inc. | 240 | 2026-10-15 | 2026-09-08 | |
| A Clinical Study on Immunogenicity Persistence of Adsorbed 5-component Acellular Pertussis, Diphtheria and Tetanus Combined Vaccine Previously received the Tdcp vaccine at age 18 and older, Previously received the Tdcp vaccine at age 12-17, Previously received the Tdcp vaccine at age 6-11 - Diphtheria, Tetanus | Not yet recruiting | CanSino Biologics Inc. | 160 | 2026-10-15 | 2026-08-04 | |
| A Phase I/II Clinical Trial of the Diphtheria, Tetanus, Acellular Component Pertussis and Sabin Inactivated Poliomyelitis Vaccine Adsorbed Diphtheria, Tetanus, Acellular Component Pertussis and Sabin Inactivated Poliomyelitis Vaccine Adsorbed, Diphtheria, Tetanus and Acellular Component Pertussis Combined Vaccine, Diphtheria, Tetanus and Acellular Component Pertussis Combined Vaccine+Inactivated Poliomyelitis Vaccine Made From Sabin Strains - Diphtheria, Pertussis | Phase 1 / Phase 2 | Recruiting | Institute of Medical Biology, Chinese Academy of Medical Sciences | 380 | 2026-10-11 | 2026-10-23 |
| Study of BK1803 in Healthy Infants BK1803, GOBIK Aqueous Suspension Syringes, Bimmugen® Injection - Pertussis, Diphtheria | Phase 3 | Not yet recruiting | Tanabe Pharma Corporation | 344 | 2026-10-01 | 2026-08-28 |
| A Phase II Clinical Trial of Absorbed Acellular Pertussis (Two-Component) Diphtheria-Tetanus Combined Vaccine (For Adults and Adolescents) Tdap vaccine, Placebo - Pertussis (Whooping Cough), Diphtheria | Phase 2 | Recruiting | Changchun BCHT Biotechnology Co. | 420 | 2026-08-12 | 2026-10-26 |
| A First in Human Study Investigating the Safety of an Unloaded and Loaded (With a Tetanus-containing Vaccine Booster) Microneedle Patch in Healthy Adults Microneedle Patch, Tetanus-containing vaccine - Vaccine Delivery, Tetanus | Phase 4 | Not yet recruiting | Microneedle Solutions Ltd | 30 | 2026-08-01 | 2026-06-03 |
| A Study on the Immune Response and Safety of a Combined Vaccine Against Diphtheria, Tetanus and Acellular Pertussis (dTpa) in Japanese Healthy Pregnant Women dTpa - Diphtheria-Tetanus-acellular Pertussis Vaccines | Phase 3 | Active not recruiting | GlaxoSmithKline | 102 | 2026-06-29 | 2026-09-08 |
| A Phase Ⅲ Clinical Study of SNA02-48 Injection SNA02-48, Human tetanus immunoglobulin (HTIG) - Tetanus | Phase 3 | Not yet recruiting | Sinovac Life Sciences Co., Ltd. | 600 | 2026-06-28 | 2026-06-08 |
| Maternal Immunization With Tetanus Toxoid, Reduced Diphtheria Toxoid, Reduced-dose (2 µg) Recombinant Pertussis Vaccine (TdaP2gen) and Its Effect on the Immune Response in Thai Infants up to 15-18 Months Old Maternal TdaP2gen vaccine, Infant Acellular Pertussis-containing Vaccine, Infant Whole-cell Pertussis-containing Vaccine - Pertussis, Diphtheria | Phase 4 | Not yet recruiting | Chiang Mai University | 320 | 2026-05-26 | 2026-06-02 |
| Phase I Clinical Trial of Adsorbed Tetanus Vaccine Tetanus Vaccine, Adsorbed - Tetanus | Phase 1 | Active not recruiting | Aimei Vacin BioPharm (Zhejiang) Co., Ltd. | 80 | 2026-05-21 | 2026-09-22 |
| A Phase I Clinical Trial of Absorbed Acellular Pertussis (Two-Component) Diphtheria-Tetanus Combined Vaccine (For Adults and Adolescents) Tdap vaccine - Pertussis (Whooping Cough), Diphtheria | Phase 1 | Not yet recruiting | Changchun BCHT Biotechnology Co. | 96 | 2026-04-20 | 2026-03-25 |
| Tetanus Severity Score for Prediction of Mortality in Manifest Tetanus Tetanus Severity Score (TSS), Philips Score, Dakar Score - Tetanus, Manifest | Recruiting | Ain Shams University | 115 | 2026-04-15 | 2026-09-29 | |
| Phase I/II Clinical Trial of Diphtheria-Tetanus-Pertussis (Reduced Dose) Vaccine low-dose Tetanus, Diphtheria and Acellular Component Pertussis Vaccine Adsorbed (Reduced Antigens Content), high-dose Tetanus, Diphtheria and Acellular Component Pertussis Vaccine Adsorbed (Reduced Antigens Content), Tetanus, Diphtheria and Acellular Pertussis Vaccine - Tetanus, Diphtheria and Acellular Pertussis Vaccination, Tetanus | Phase 1 / Phase 2 | Not yet recruiting | Institute of Medical Biology, Chinese Academy of Medical Sciences | 660 | 2026-03-12 | 2026-02-18 |
| TETANUS Antibody Detection in Saliva Study Point of care, saliva-based lateral flow test, Blood based immunoassay - Tetanus | Not applicable | Not yet recruiting | University of Birmingham | 390 | 2026-02-01 | 2026-03-03 |
| A Phase 4 Study to Evaluate the Effectiveness and Safety of Siltartoxatug Injection for Tetanus Prophylaxis Following Injury Siltartoxatug Injection, HTIG/TAT/F(ab')₂ - Tetanus | Recruiting | Zhuhai Trinomab Pharmaceutical Co., Ltd. | 6000 | 2026-01-14 | 2026-07-27 | |
| Enhancing Maternal Vaccine Knowledge and Uptake: The InTroDuce-Programme Trial Influenza and Tdap Vaccination Educational and Learning Module - Vaccination Uptake, Knowledge | Not applicable | Recruiting | Universiti Putra Malaysia | 351 | 2026-01-13 | 2026-05-01 |
| Clinical Trial of the Adsorbed Acellular Pertussis (Tricomponent) DTaP-Haemophilus Influenzae Type b (Conjugate)-ACYW135 Group Meningococcal (Conjugate) Combined Vaccine Adsorbed Acellular Pertussis (3-Component) Diphtheria-Tetanus-Pertussis-Haemophilus influenzae type b (Conjugate)-Meningococcal Group ACYW135 (Conjugate) Combined Vaccine (DTcP-Hib-MCV4), DTcP-Hib-MCV4, Adsorbed Acellular Pertussis (3-Component) Diphtheria-Tetanus-Pertussis (DTcP) - Diphtheria, Tetanus and Acellular Pertussis, Epidemic Meningitis | Phase 1 | Recruiting | CanSino Biologics Inc. | 260 | 2025-12-19 | 2025-12-31 |
| Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective Dengue, Chikungunya | Recruiting | Institut Pasteur du Cambodge | 10000 | 2025-12-18 | 2026-01-22 | |
| Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Recombinant Human Anti-Tetanus Toxin Monoclonal Antibody Injection Recombinant Human Anti-Tetanus Toxin Monoclonal Antibody Injection, Human Tetanus Immunoglobulin, Placebo - Tetanus | Phase 1 | Enrolling by invitation | Lanzhou Institute of Biological Products Co., Ltd | 68 | 2025-08-18 | 2026-01-28 |
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Diphtheria (244) · Whooping Cough (167) · Poliomyelitis (114) · Haemophilus Infections (106) · Hepatitis B (105) · Measles (9) · Influenza, Human (8) · Meningococcal Infections (8) · Meningitis (7) · Virus Diseases (7) · Pneumococcal Infections (6) · Meningitis, Meningococcal (5) · Bacterial Infections (4) · HIV Infections (4)
Bacterial Infections and Mycoses (304) · Clostridium Infections (304) · Gram-Positive Bacterial Infections (304) · Infections (303) · Bacterial Infections (300) · Actinomycetales Infections (245) · Corynebacterium Infections (244) · Gram-Negative Bacterial Infections (207) · Respiratory Tract Diseases (173) · Respiratory Tract Infections (172) · Bordetella Infections (167) · Virus Diseases (163) · RNA Virus Infections (131) · Nervous System Diseases (127) · Neuroinflammatory Diseases (123)
Tetanus Toxoid (61) · diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae b conjugate-hepatitis B vaccine (29) · Boostrix (25) · Diphtheria-Tetanus-acellular Pertussis Vaccines (24) · adacel (24) · Hiberix (12) · Pentavac (12) · Vaccines, Combined (11) · pentacel (10) · 13-valent pneumococcal vaccine (9) · Poliovirus Vaccine, Inactivated (9) · DTaP-IPV-HB-PRP-T vaccine (7) · Diphtheria-Tetanus Vaccine (7) · Heptavalent Pneumococcal Conjugate Vaccine (7) · Haemophilus influenza type b polysaccharide vaccine-tetanus toxin conjugate (6)
GlaxoSmithKline (102) · Sanofi Pasteur, a Sanofi Company (56) · Sanofi (18) · CanSino Biologics Inc. (10) · National Institute of Allergy and Infectious Diseases (NIAID) (9) · LG Chem (7) · Merck Sharp & Dohme LLC (7) · Zhuhai Trinomab Pharmaceutical Co., Ltd. (5) · Institute of Medical Biology, Chinese Academy of Medical Sciences (4) · Crucell Holland BV (3) · Novartis Vaccines (3) · Oxford University Clinical Research Unit, Vietnam (3) · Shantha Biotechnics Limited (3) · Sinovac Life Sciences Co., Ltd. (3) · Tanabe Pharma Corporation (3)
United States (61) · China (45) · Philippines (18) · South Korea (17) · Germany (15) · Canada (13) · France (11) · Thailand (11) · Finland (9) · India (9) · Italy (8) · Japan (8) · Vietnam (8) · Spain (7) · Russia (6)
Raman Rao, MD (3) · Chuanlin Wang, MD (2) · Eva Netterlid (2) · Maria RZ Capeding, MD (2) · Shiguang Lei (2) · Yanxia Wang (2) · Abdul M Kazi, MBBS,MPH (1) · Adam Thaler, DO (1) · Aitana Juan Giner, MSc (1)
PMID 17716936, PMID 20657177, PMID 25882172, PMID 28340322, PMID 14670310, PMID 15882526, PMID 16511379, PMID 16760795, PMID 16816555, PMID 17090650, PMID 18431498, PMID 18752430, PMID 19095033, PMID 19117896, PMID 19952980, PMID 20189491, PMID 20439595, PMID 20448468, PMID 20616762, PMID 20950456, PMID 20955461, PMID 21134450, PMID 21219984, PMID 21372751, PMID 21441781, PMID 21807056, PMID 21817954, PMID 21945698, PMID 22001281, PMID 22115634, PMID 22157567, PMID 22197012, PMID 22273029, PMID 22349525, PMID 22475857, PMID 22531237, PMID 22691430, PMID 23032160, PMID 23077849, PMID 23241989, PMID 23783081, PMID 23966556, PMID 24176498, PMID 24341659, PMID 24346596, PMID 24794369, PMID 24835247, PMID 25008903, PMID 25230939, PMID 25269669
2014 (3), 2015 (2), 2008 (1), 2009 (1), 2016 (1), 2018 (1), 2019 (1), R21AI141822 (1)