156 completed, 19 unknown, 12 recruiting, 9 terminated. 58 Phase 1, 52 Phase 3, 37 Not applicable, 35 Phase 2, 21 Phase 4.
Follow Fluconazole: new trials by email Literature Review of Fluconazole trials Research Report on Fluconazole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimizing Care for Cryptococcal Antigenemia: Evaluation of Short Course Fluconazole and ART Timing Among CrAg+ Persons With Low Titers Immediate ART Initiation, Delayed ART Initiation, 10-Week Fluconazole - Cryptococcal Antigenemia, HIV-1-infection | Phase 3 | Not yet recruiting | University of Minnesota | 505 | 2027-01-05 | 2026-09-03 |
| A Single-center, Randomized, Open-label, Parallel-design Clinical Study to Evaluate the Pharmacokinetic Effects of Itraconazole, Fluconazole or Efavirenz on a Single Dose of Clifutinib in Healthy Participants Clifutinib, Itraconazole, fluconazole - Healthy Adult Subject | Phase 1 | Not yet recruiting | Sunshine Lake Pharma Co., Ltd. | 80 | 2026-12-31 | 2026-04-27 |
| Drug-Drug Interactions of JMKX003142 in Healthy Participants JMKX003142 tablets, Fluconazole Capsules, Cocktail Substrates (Midazolam Oral Solution, Rosuvastatin Calcium Tablets, and Digoxin Tablets) - ADPKD (Autosomal Dominant Polycystic Kidney Disease) | Phase 1 | Not yet recruiting | Jemincare | 112 | 2026-05-11 | 2026-05-04 |
| The LISA (Lactoferrin InStead of Antibiotics/Antifungals) Feasibility Study Vaginal lactoferrin, Usual care - Bacterial Vaginosis, Candida Vaginal | Not applicable | Recruiting | Guy's and St Thomas' NHS Foundation Trust | 114 | 2026-04-16 | 2026-05-29 |
| A Study of Olomorasib (LY3537982) in Healthy Participants Olomorasib, Fluconazole - Healthy | Phase 1 | Completed | Eli Lilly and Company | 15 | 2026-03-02 | 2026-05-19 |
| A Study to Learn How Fluconazole, Carbamazepine and Itraconazole Affect How the Body Processes ASP3082 in Healthy Adults Setidegrasib, Fluconazole, Carbamazepine - Healthy Volunteer | Phase 1 | Active not recruiting | Astellas Pharma Global Development, Inc. | 54 | 2026-02-03 | 2026-08-27 |
| Effect of Antifungals on the Intestinal Microbiome - a Randomized, Controlled, Proof-of-concept Trial Fluconazole 200mg tab - Gut Microbiome, Healthy Adult Male | Early Phase 1 | Not yet recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 50 | 2026-01-01 | 2025-12-19 |
| Comparing the Efficacy of Oral Fluconazole Versus Oral Itraconazole in Treating Resistant Tinea Corporis Itraconazole (200 mg), Fluconazole 150 mg - Tinea Corporis, Dermatophytosis | Phase 4 | Recruiting | Urooj Fatima | 126 | 2025-11-01 | 2026-01-15 |
| The Role of EDHFs on Blood Pressure Following a Bout of Prolonged Sitting Placebo, Fluconazole 150 mg - Cardiovascular | Not applicable | Recruiting | Université de Sherbrooke | 40 | 2025-11-01 | 2026-04-13 |
| Rezafungin Prophylaxis in Liver Transplant Rezafungin, Standard of care antifungal prophylaxis - Liver Transplant Infection, Fungal Infection | Phase 3 | Enrolling by invitation | Fernanda P Silveira, MD, MS | 385 | 2025-10-15 | 2026-09-29 |
| A Study to Learn if the Study Medicine Called Fluconazole Changes How the Other Body Processes the Study Medicine PF-07248144 PF-07248144, Fluconazole - Healthy Adults | Phase 1 | Completed | Pfizer | 12 | 2025-08-26 | 2026-06-09 |
| Comparison of Efficacy of Oral Fluconazole Versus Oral Itraconazole in the Treatment of Pityriasis Versicolor Fluconazole, Itraconazole - Pityriasis Versicolor | Phase 4 | Recruiting | Khyber Teaching Hospital | 106 | 2025-03-01 | 2025-04-10 |
| A Drug-Drug Interaction Study to Evaluate the Effects of Itraconazole, Carbamazepine, Quinidine and Fluconazole on the Pharmacokinetics and Safety of EDP-323. EDP-323, Itraconazole, carbamazepine - RSV Infection, Drug Drug Interaction (DDI) | Phase 1 | Completed | Enanta Pharmaceuticals, Inc | 48 | 2025-01-27 | 2025-07-01 |
| A Study of the Efficacy and Safety of WXSH0102 in Treating VCC Patients WXSH0102/placebo, fluconazole capsules/placebo - Vaginitis | Phase 2 | Recruiting | Cisen Pharmaceutical CO., LTD. | 108 | 2025-01-13 | 2025-02-13 |
| Clinical Trial Testing Whether Targeted Antibiotic Prophylaxis Can Reduce Infections After Cystectomy Compared to Empiric Prophylaxis Pivmecillinam, Amoxicillin clavulanic acid, Amoxicillin - Cystectomy, Bladder Cancer Requiring Cystectomy | Phase 4 | Recruiting | Copenhagen University Hospital, Rigshospitalet | 248 | 2025-01-07 | 2025-01-09 |
| A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis. Fosmanogepix, Caspofungin, Fluconazole - Candidemia, Candidiasis, Invasive | Phase 3 | Recruiting | Basilea Pharmaceutica | 450 | 2024-12-11 | 2026-10-19 |
| Testing the Role of Anti-fungal Therapy in Improving the Response to Therapies for Crohn's Disease Fluconazole, Placebo, IL-23 Therapy - Crohn's Disease, Inflammatory Bowel Diseases | Phase 3 | Recruiting | Weill Medical College of Cornell University | 120 | 2024-10-04 | 2026-08-20 |
| Safety and Efficacy of Intralesional 0.5% Triamcinolone Acetonide in 0.2% Fluconazole Solution vs 0.1% Topical Mometasone Furoate With 2% Miconazole Nitrate Cream in the Treatment of Chronic Paronychia: An Intraindividual Randomized Controlled Trial. Intralesional triamcinolone acetonide and fluconazole, Topical mometasone furoate and miconazole nitrate, Elica-M® - Chronic Paronychia | Phase 3 | Active not recruiting | Cairo University | 21 | 2024-08-17 | 2025-12-31 |
| Introduction of Mycotic Prophylaxis At Cystectomy Trial. Fluconazole, Isotonic saline solution - Cystectomy | Phase 4 | Recruiting | Copenhagen University Hospital, Rigshospitalet | 420 | 2024-06-24 | 2026-08-12 |
| A Study to Assess LY4100511 (DC-853) in Healthy Adult Participants LY4100511 (DC-853), Itraconazole, Fluconazole - Healthy | Phase 1 | Completed | DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company | 50 | 2024-04-03 | 2025-04-27 |
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HIV Infections (39) · Acquired Immunodeficiency Syndrome (33) · Meningitis, Cryptococcal (27) · Mycoses (26) · Candidiasis (23) · AIDS-Related Opportunistic Infections (22) · Candidiasis, Vulvovaginal (21) · Cryptococcosis (18) · Meningitis (18) · Candidemia (13) · Candidiasis, Invasive (12) · Candidiasis, Oral (8) · AIDS-Related Complex (6) · Fungemia (6) · Invasive Fungal Infections (6)
Pfizer (33) · National Institute of Allergy and Infectious Diseases (NIAID) (15) · Scynexis, Inc. (5) · University of Minnesota (5) · Boehringer Ingelheim (4) · Jiangsu HengRui Medicine Co., Ltd. (4) · Astellas Pharma Inc (3) · Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (3) · Eli Lilly and Company (3) · Enanta Pharmaceuticals, Inc (3) · ANRS, Emerging Infectious Diseases (2) · Alexion Pharmaceuticals, Inc. (2) · Bristol-Myers Squibb (2) · Cairo University (2) · Children's Oncology Group (2)
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