63 completed, 10 unknown, 8 terminated, 3 not yet recruiting. 24 Phase 3, 10 Phase 2, 10 Phase 4, 8 Not applicable, 6 Phase 1.
Follow Fungemia: new trials by email Literature Review of Fungemia trials Research Report on Fungemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Diagnostic Accuracy and Clinical Performance of the UllCORE Bloodstream Infection (BSI) Test UllCORE BSI Test - Blood Stream Infection, Blood Stream Infections | Recruiting | Deepull Diagnostics S.L. | 1500 | 2026-09-21 | 2026-10-08 | |
| Shortening Treatment Duration in Uncomplicated Candidemia: the CanTEN Trial Caspofungin only within the study, Caspofungin for 3 days within the study, Placebo only within the study - Candidemia, Invasive Candidiasis | Phase 4 | Not yet recruiting | Oliver Cornely, MD | 420 | 2026-09-01 | 2026-09-01 |
| Clinical Efectiveness of a Multiplex PCR-Based Rapid Diagnostic Method in Bloodstream Infections Multiplex PCR-Based Rapid Diagnostic Test, Standard Microbiological Diagnostic Methods - Bloodstream Infections, Bacteremia and Sepsis | Recruiting | Istanbul Medipol University Hospital | 300 | 2026-01-01 | 2026-02-13 | |
| A Randomized Study of a Short Duration Therapy for Candidemia Standard of Care (SOC), Shortened duration of antifungal therapy - CANDIDEMIA | Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 362 | 2025-07-01 | 2025-03-05 |
| A Study Comparing Short-course Antifungal Therapy (SCAT) 7 Day vs Standard 14 Day Antifungal Therapy for Uncomplicated Candidemia Antifungal treatment - Candidemia | Not yet recruiting | Augusta University | 150 | 2025-05-01 | 2025-04-04 | |
| Performance Evaluation of the Fujifilm Wako Beta-D-glucan Technique in the Diagnosis of Major Invasive Fungal Infections (IFI) Beta-1,3/1,6-D-Glucan - Candidemia, Aspergillosis Invasive | Completed | Central Hospital, Nancy, France | 280 | 2024-12-17 | 2025-12-09 | |
| A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis. Fosmanogepix, Caspofungin, Fluconazole - Candidemia, Candidiasis, Invasive | Phase 3 | Recruiting | Basilea Pharmaceutica | 450 | 2024-12-11 | 2026-10-19 |
| Metagenomic Sequencing for the Identification of Pathogens in Febrile Neutropenic Patients Metagenomic diagnosis (mNGS, DISQVER) - Immunodepressed Patients (Hemato-oncology) | Not applicable | Terminated | Poitiers University Hospital | 184 | 2024-01-12 | 2026-08-25 |
| A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole SCY-078, Fluconazole, Echinocandin - Candidiasis, Invasive, Candidemia | Phase 3 | Terminated | Scynexis, Inc. | 68 | 2022-08-03 | 2026-08-10 |
| Candida PCR Diagnosis Strategy in Patients From Intensive Care Units Diagnosis strategy based on C. glabrata / krusei PCR - Candida | Not applicable | Completed | University Hospital, Toulouse | 48 | 2022-05-19 | 2026-08-11 |
| Safety and Efficacy of Interferon-Gamma 1b in Patients With Candidemia Interferon Gamma-1B - Candidemia | Phase 2 | Completed | Radboud University Medical Center | 65 | 2022-03-31 | 2026-06-22 |
| Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation Rezafungin for Injection, Posaconazole, Fluconazole - Candidemia, Mycoses | Phase 3 | Completed | Mundipharma Research Limited | 602 | 2020-05-11 | 2026-04-13 |
| An Open-label Study of APX001 for Treatment of Patients With Candidemia/Invasive Candidiasis Caused by Candida Auris APX001 - Candidemia, Invasive Candidiases | Phase 2 | Completed | Basilea Pharmaceutica | 9 | 2019-12-13 | 2025-09-16 |
| Assessment of Assay for Rapid Identification of Bloodstream Infections From Whole Blood RaPID/BSI Test - Bacteremia, Candidemia | Unknown | HelixBind, Inc. | 225 | 2019-10-01 | 2019-11-01 | |
| Clinical and Medico-economic Evaluation of a Rapid Test (ePlex-BCID®, GenMark) for the Diagnosis of Bacteremia and Fungemia. Multiplex PCR, Current strategy alone - Bacteremia Sepsis, Fungemia | Not applicable | Completed | University Hospital, Grenoble | 312 | 2019-06-20 | 2021-11-03 |
| Dosage of Plasma 1, 3-β-D-glucan for the Diagnosis of Candidemia. BDG analysis - Infection, Fungal | Unknown | Assistance Publique - Hôpitaux de Paris | 2000 | 2018-12-12 | 2021-01-26 | |
| Echinocandins Versus Azoles for Candidemia Treatment Echinocandin treatment, Triazole treatment - Candidemia | Completed | Hospices Civils de Lyon | 79 | 2018-11-01 | 2020-03-04 | |
| Study of Rezafungin Compared to Caspofungin in Subjects With Candidemia and/or Invasive Candidiasis Rezafungin for Injection, Caspofungin, Fluconazole - Candidemia, Mycoses | Phase 3 | Completed | Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 199 | 2018-10-07 | 2023-01-06 |
| An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemia APX001 - Candidemia | Phase 2 | Completed | Basilea Pharmaceutica | 21 | 2018-10-03 | 2025-09-16 |
| Open-Label Study to Evaluate the Efficacy and Safety of Oral Ibrexafungerp (SCY-078) in Patients With Candidiasis Caused by Candida Auris (CARES) SCY-078 - Candidiasis, Invasive, Candidemia | Phase 3 | Completed | Scynexis, Inc. | 30 | 2017-11-15 | 2024-07-03 |
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Candidemia (68) · Candidiasis, Invasive (28) · Candidiasis (24) · Mycoses (21) · Sepsis (13) · Torulopsis (13) · Bacteremia (11) · Aspergillosis (9) · Invasive Fungal Infections (7) · Neutropenia (3) · Disease Susceptibility (2) · Fever (2) · Pathologic Processes (2) · Pneumonia, Pneumocystis (2)
Bacterial Infections and Mycoses (90) · Pathological Conditions, Signs and Symptoms (90) · Infections (89) · Inflammation (89) · Pathologic Processes (88) · Systemic Inflammatory Response Syndrome (88) · Invasive Fungal Infections (83) · Sepsis (77) · Mycoses (69) · Candidiasis (48) · Candidiasis, Invasive (40) · Bacterial Infections (12) · Disease Attributes (4) · Hematologic Diseases (4)
Fluconazole (15) · Micafungin (15) · Anidulafungin (14) · Caspofungin (9) · Voriconazole (9) · Injections (4) · ibrexafungerp (3) · Rezafungin (2) · liposomal amphotericin B (2) · Amphotericin B (1) · Antimicrobial Stewardship (1) · Echinocandins (1) · Interferon-gamma (1) · Itraconazole (1) · Standard of Care (1)
Pfizer (15) · Astellas Pharma Inc (8) · National Cancer Institute (NCI) (5) · Basilea Pharmaceutica (3) · Scynexis, Inc. (3) · T2 Biosystems (3) · Assistance Publique - Hôpitaux de Paris (2) · Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (2) · Radboud University Medical Center (2) · University of Pittsburgh (2) · AM-Pharma (1) · Accelerate Diagnostics, Inc. (1) · Amsterdam UMC, location VUmc (1) · Astellas Pharma China, Inc. (1) · Astellas Pharma Global Development, Inc. (1)
United States (43) · France (18) · Italy (15) · Germany (14) · Spain (12) · Canada (11) · Belgium (10) · Brazil (8) · China (8) · Greece (8) · Netherlands (7) · South Korea (7) · Taiwan (7) · Bulgaria (6) · Israel (6)
David Angulo, MD (3) · Marc Engelhardt (2) · Peter Pappas, MD (2) · Alexandra Hill, MD (1) · Arunaloke Chakrabarti, MD (1) · Barbara D Alexander, MD (1) · Belen Padilla, MD (1) · Christine B Teng, MSc (1) · Claudia Spies, Prof., MD (1) · Constance Bridges, B.S., MBA (1)
PMID 28459966, PMID 28597967, PMID 33891293, PMID 31280481, PMID 21147825, PMID 23315320, PMID 33438477, PMID 38008099, PMID 38502709, PMID 39468640, PMID 39529079, PMID 41940006, PMID 16127033, PMID 17568028, PMID 17719934, PMID 19804626, PMID 22018278, PMID 22469884, PMID 22879929, PMID 23676114, PMID 23710653, PMID 24559321, PMID 24669841, PMID 25097069, PMID 25376267, PMID 25586686, PMID 25678411, PMID 25902926, PMID 26050015, PMID 26197846, PMID 26976872, PMID 27287231, PMID 27872072, PMID 29367293, PMID 29438475, PMID 29596222, PMID 30289478, PMID 30418357, PMID 31367384, PMID 32032174, PMID 32955088, PMID 34554228, PMID 36442484, PMID 37022196, PMID 37596890, PMID 37773627, PMID 38985561, PMID 39259571, PMID 39843376, PMID 41194465
2008 (2), 2015 (2), 2009 (1), 2017 (1), KL2TR000136 (1), U01CK000692 (1), UM1AI104681 (1)