487 completed, 139 unknown, 108 recruiting, 55 terminated. 248 Not applicable, 94 Phase 3, 78 Phase 4, 42 Phase 2, 21 Phase 1.
Follow Embolism: new trials by email Literature Review of Embolism trials Research Report on Embolism
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Augmented Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for PE Ultrasound-facilitated, catheter-directed lower-dose fibrinolysis, Tissue Plasminogen Activator - Pulmonary Embolism, Right Ventricular Dysfunction | Suspended | Brigham and Women's Hospital | 60 | 2027-01-01 | 2026-01-21 | |
| Exclusion of Left Atrial Appendage Thrombus in Emergency Department Patients With Atrial Fibrillation Undergoing CT to Assess for Pulmonary Embolus: A Feasibility Study Delayed Un-gated CT Scan for Left Atrial Appendage Thrombus, Delayed Gated CT Scan for Left Atrial Appendage Thrombus - Atrial Fibrillation (AF), Pulmonary Embolism (PE) | Not applicable | Not yet recruiting | Northwell Health | 60 | 2026-11-01 | 2026-10-26 |
| Edoxaban Versus Apixaban in Cancer-Associated Venous Thromboembolism edoxaban, Apixaban - Venous Thromboembolism, Active Cancer | Phase 4 | Not yet recruiting | Samsung Medical Center | 2300 | 2026-11-01 | 2026-10-01 |
| Reduced-Dose Thrombolysis in Intermediate-Risk Pulmonary Embolism With High-Risk Features Alteplase, Standard Anticoagulation - Pulmonary Embolism | Phase 3 | Not yet recruiting | China National Center for Cardiovascular Diseases | 270 | 2026-11-01 | 2026-11-04 |
| Clinical Management and Outcomes After Lung Scintigraphy for Suspected Pulmonary Embolism in the Emergency Department Pulmonary Perfusion Scintigraphy - Pulmonary Embolism (Diagnosis) | Recruiting | Antalya Health Sciences University | 100 | 2026-10-10 | 2026-10-29 | |
| The ReCAna for Lower ExtremIty Venous OBstructions and In-StEnt Restenosis Registry Recanalization and debulking - Chronic Venous Disease, Chronic Venous Insufficiency, CVI | Not yet recruiting | Intervene, Inc. | 500 | 2026-10-01 | 2026-10-23 | |
| Pilot Study Evaluating Catheter Directed Thrombolysis Device in Acute Intermediate Risk Pulmonary Embolism Thrombolysis Catheter - Pulmonary Embolism (PE), Pulmonary Embolism With Right Ventricle Enlargement | Not applicable | Not yet recruiting | Flow Medical Solutions, Inc. | 20 | 2026-10-01 | 2026-07-02 |
| Vortosiran for VTE Prevention Vortosiran, Placebo - Venous Thromboembolism (VTE), Cancer | Phase 2 | Not yet recruiting | Ribocure Pharmaceuticals AB | 150 | 2026-10-01 | 2026-09-30 |
| CTEPH Differential Diagnosis Assisted by Enhanced Large Language Model Support Locked CTEPH-LLM Diagnostic Decision Support - Chronic Thromboembolic Pulmonary Hypertension (CTEPH), Acute Pulmonary Embolism (PE) | Not applicable | Not yet recruiting | China-Japan Friendship Hospital | 60 | 2026-10-01 | 2026-10-29 |
| Multimodal Physiologic State Intelligence Study OMNIPHYS Multimodal Ultrasound Imaging System - Heart Failure, Cardiomyopathies | Enrolling by invitation | Truway Health, Inc. | 25000 | 2026-09-02 | 2026-09-10 | |
| Risk Factors of Venous Thrombotic Event in Interstitial Lung Disease Interstitial Lung Disease, Venous Thromboembolism | Not yet recruiting | Sohag University | 100 | 2026-09-01 | 2026-09-22 | |
| Decision Aid for Anticoagulation Duration After Unprovoked Venous Thromboembolism DECIDE-VTE Patient Decision Aid - Venous Thromboembolism (VTE), Deep Vein Thrombosis (DVT) | Not applicable | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 850 | 2026-09-01 | 2026-06-24 |
| 18F-S2P PET Imaging in the Evaluation of Large Artery Atherosclerosis 18F-S2P - Large-Artery Atherosclerosis (Embolus/Thrombosis) | Not applicable | Not yet recruiting | First Affiliated Hospital of Zhejiang University | 200 | 2026-09-01 | 2026-09-11 |
| Treatment and Secondary Prevention of Venous Thromboembolism (VTE) in Adult Participants With Solid and Hematologic Cancers REGN7508, Apixaban - Venous Thromboembolism (VTE) | Phase 3 | Recruiting | Regeneron Pharmaceuticals | 1600 | 2026-08-26 | 2026-11-05 |
| Vibrato Aspiration System - Simple, Intuitive Approach to Clot Removal in Acute Pulmonary Embolism - a Safety & Feasibility Study Mechanical Thrombectomy - Pulmonary Embolism Acute | Not applicable | Recruiting | Vicora, Inc. | 10 | 2026-08-21 | 2026-08-25 |
| Smart Technology Facilitated Patient-centered Care for Patients With Pulmonary Thromboembolism mobile venous thromboembolism application (mVTEA) - Venous Thromboembolism, Pulmonary Thromboembolisms | Not applicable | Recruiting | Navy General Hospital, Beijing | 2972 | 2026-08-20 | 2026-09-09 |
| Predictors of Pulmonary Embolism in Interstitial Lung Disease With Worsening Symptoms Pulmonary Embolism, Interstitial Lung Disease | Not yet recruiting | Assiut University | 70 | 2026-08-01 | 2026-07-27 | |
| Extended Prophylactic Anticoagulation Following Spinal Surgery for Metastatic Disease Apixaban - Venous Thromboembolism (VTE), Deep Vein Thrombosis (DVT) | Phase 4 | Not yet recruiting | James Bayley | 50 | 2026-08-01 | 2026-07-20 |
| Prospective Cohort of Acute Cardiology Referrals in an Ambulatory Day-Hospital Setting Acute Coronary Syndromes, Heart Failure | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 25000 | 2026-08-01 | 2026-06-30 | |
| Pulmonary Embolism in Patients With Acute Heart Failure (PEHF Study) Systematic screening for pulmonary embolism in all patients using a guideline-recommended diagnostic algorithm - Acute Heart Failure (AHF), Pulmonary Embolism (Diagnosis) | Not applicable | Recruiting | University Hospital, Angers | 740 | 2026-07-15 | 2026-07-17 |
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Pulmonary Embolism (783) · Venous Thrombosis (302) · Venous Thromboembolism (190) · Thrombosis (96) · Atrial Fibrillation (64) · Stroke (45) · Thromboembolism (41) · Neoplasms (31) · Disease (29) · COVID-19 (27) · Hemorrhage (25) · Cardiovascular Diseases (24) · Hypertension, Pulmonary (21) · Acute Coronary Syndrome (18)
Vascular Diseases (869) · Embolism and Thrombosis (861) · Cardiovascular Diseases (855) · Respiratory Tract Diseases (780) · Lung Diseases (768) · Thrombosis (263) · Pathological Conditions, Signs and Symptoms (226) · Pathologic Processes (198) · Thromboembolism (177) · Heart Diseases (137) · Nervous System Diseases (90) · Central Nervous System Diseases (71) · Brain Diseases (70) · Cerebrovascular Disorders (63)
Rivaroxaban (48) · Enoxaparin (44) · Warfarin (35) · apixaban (30) · Heparin, Low-Molecular-Weight (25) · Heparin (24) · Dalteparin (22) · Tissue Plasminogen Activator (20) · Fondaparinux (14) · Aspirin (13) · edoxaban (13) · Tinzaparin (11) · Blood Specimen Collection (10) · Dabigatran (10) · Standard of Care (10)
Brigham and Women's Hospital (26) · Bayer (24) · Assistance Publique - Hôpitaux de Paris (20) · University Hospital, Brest (19) · Assiut University (14) · Centre Hospitalier Universitaire de Saint Etienne (10) · McMaster University (10) · University Hospital, Angers (10) · Bristol-Myers Squibb (9) · Ottawa Hospital Research Institute (9) · University of Utah (9) · Wake Forest University Health Sciences (9) · China-Japan Friendship Hospital (8) · Inari Medical (8) · Boston Scientific Corporation (7)
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Samuel Z. Goldhaber, MD (6) · Gregory Piazza, MD, MS (4) · Gualtiero Palareti, MD (4) · Samuel Z Goldhaber, MD (4) · Shirley Wang, PhD, ScM (4) · Cecilia Becattini, MD (3) · Christopher Puccini, MD (3)
PMID 33779986, PMID 29976287, PMID 33086312, PMID 33337539, PMID 34127618, PMID 35570249, PMID 38941511, PMID 40163217, PMID 19920268, PMID 20696966, PMID 22863355, PMID 23279103, PMID 23306310, PMID 24876082, PMID 27959702, PMID 28617144, PMID 28762617, PMID 29452956, PMID 29649055, PMID 30633959, PMID 33502773, PMID 33857326, PMID 34622445, PMID 35244208, PMID 35876829, PMID 36413425, PMID 37591523, PMID 39454884, PMID 40391253, PMID 40925065, PMID 10826469, PMID 11982463, PMID 12131409, PMID 14715365, PMID 15262836, PMID 15319720, PMID 16009794, PMID 16307934, PMID 16432055, PMID 16456434, PMID 16531616, PMID 16598645, PMID 16775259, PMID 16926353, PMID 16960155, PMID 17065639, PMID 17113889, PMID 17215729, PMID 17289685, PMID 17332445
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