15 completed, 2 unknown, 1 recruiting, 1 suspended. 10 Not applicable, 3 Phase 2, 3 Phase 4, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 6, Unknown 2, Recruiting 1, Suspended 1 |
| Phase 2 | 3 | Completed 3 |
| Phase 4 | 3 | Completed 3 |
| Phase 3 | 2 | Completed 2 |
Follow Arthropathy of Knee Joint: new trials by email Literature Review of Arthropathy of Knee Joint trials Research Report on Arthropathy of Knee Joint
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Naldebain for Pain Management After Knee Arthroplasty Nalbuphine Sebacate (Naldebain), Placebo medication - Arthropathy of Knee Joint | Phase 4 | Completed | Kaohsiung Medical University Chung-Ho Memorial Hospital | 80 | 2022-04-06 | 2023-03-27 |
| Kaolin-based Hemostatic Gauze in Total Knee Arthroplasty Tranexamic acid injection, apply the QCG, apply surgical gauze - Total Blood Loss, Arthropathy of Knee Joint | Phase 4 | Completed | Chang Gung Memorial Hospital | 140 | 2022-03-16 | 2026-07-22 |
| Prospective Functional, Gait, and Outcome Comparison Study of Medial Pivot Versus Single Radius Design for Total Knee Arthroplasty MicroPort Evolution Medial-Pivot Knee System (Cruciate-substituting), Stryker Triathlon Tritanium Knee System (Condylar Stabilizing) - Osteoarthritis, Knee, Knee Osteoarthritis | Not applicable | Recruiting | LifeBridge Health | 100 | 2021-02-01 | 2025-01-22 |
| A Personalized Prehabilitation Intervention In Elective Joint Replacement Surgery personalized prehabilitation - Arthropathy of Knee Joint, Arthropathy of Hip Joint | Not applicable | Suspended | University of Pennsylvania | 28 | 2019-10-01 | 2026-05-29 |
| Opioid-free Accelerated Recovery Total Knee Arthroplasty opioids - Arthropathy of Knee Joint | Completed | St. Elizabeth Medical Center, Utica, NY | 400 | 2018-10-01 | 2020-05-12 | |
| Regional Prophylactic Vancomycin With Restricted Tourniquet Time in Primary Total Knee Replacement Vancomycin - Arthropathy of Knee Joint | Phase 2 / Phase 3 | Completed | Mayo Clinic | 24 | 2018-09-24 | 2020-01-27 |
| The Effect of Exercise Training on Muscle Mass in Patients With Total Knee Arthroplasty Exercise - Knee Osteoarthritis, Arthropathy of Knee Joint | Not applicable | Unknown | Chang Gung Memorial Hospital | 210 | 2017-11-01 | 2020-03-16 |
| Comparison of Computer-Assisted Navigation and Conventional Instrumentation for Bilateral Total Knee Arthroplasty Computer-Assisted Navigation TKA - Arthropathy of Knee Joint | Completed | Chang Gung Memorial Hospital | 56 | 2017-11-01 | 2018-09-13 | |
| Neuromuscular Electrical Stimulation (NMES) for Improving Outcomes Following Total Knee Arthroplasty (TKA) CyMedica Orthopedics QB1 e-vive™ system - Arthropathy of Knee Joint | Not applicable | Completed | The Cleveland Clinic | 66 | 2017-01-01 | 2020-03-05 |
| Outcome After Total Knee Arthroplasty Under General or Spinal Anesthesia Spinal anesthesia with tourniquet, Spinal anesthesia without tourniquet, General anesthesia with tourniquet - Knee Osteoarthritis, Arthropathy of Knee Joint | Not applicable | Completed | Riku Antero Palanne | 402 | 2016-10-03 | 2020-01-13 |
| Postoperative Pain Management in Hospital and Following Discharge From Hospital. Arthropathy of Knee Joint | Completed | Trinity Health Of New England | 200 | 2014-07-01 | 2017-04-27 | |
| Regional Prophylactic Vancomycin in Revision Total Knee Replacement Vancomycin - Arthropathy of Knee Joint | Phase 2 / Phase 3 | Completed | Mayo Clinic | 22 | 2013-12-01 | 2016-11-25 |
| Motion Analysis of EMP Knee Versus Posterior Stabilized Knee Arthroplasty for Osteoarthritis Total Knee Arthroplasty, Motion analysis - Arthropathy of Knee Joint | Not applicable | Completed | Ottawa Hospital Research Institute | 50 | 2012-01-01 | 2015-11-18 |
| Total Knee Arthroplasty - Accelerated Recovery Without Tourniquet Total Knee Arthroplasty - Arthropathy of Knee Joint | Not applicable | Completed | Northern Orthopaedic Division, Denmark | 70 | 2011-03-01 | 2015-01-30 |
| Improving Function After Knee Arthroplasty With Weight-Bearing Biofeedback Weight-bearing biofeedback exercise, Standard of care exercise - Arthropathy of Knee Joint | Not applicable | Completed | University of Colorado, Denver | 26 | 2011-01-01 | 2019-04-23 |
| Evaluation of Optimal Dose of Local Anesthetics for Patient Controlled Continuous Femoral Nerve Block PC-FNB with basal administration of local anesthetics, PC-FNB without basal local anesthetics - Arthropathy of Knee Joint | Not applicable | Unknown | Okayama University | 60 | 2010-09-01 | 2011-07-22 |
| Local Infiltration With Bupivacaine to Increase Quality of Post-operative Pain Control in Total Knee Replacement 0.25% Bupivacaine, 0.9% normal saline - Pain, Postoperative, Arthropathy of Knee Joint | Phase 4 | Completed | Mahidol University | 60 | 2010-03-01 | 2011-06-02 |
| The Utilization of Nintendo Wii™ in Outpatient Rehabilitation Following Total Knee Replacement Wii Fit, Lower Extremity Exercise - Arthropathy of Knee Joint | Phase 2 | Completed | Manuel Gomez, MD, MSc. | 50 | 2009-05-01 | 2014-02-27 |
| Comparison of Cruciate Retaining and Posterior Stabilized Total Knee Arthroplasty Total knee replacement with cruciate retaining femoral component, Total knee replacement with cruciate substituting femoral component - Osteoarthritis, Knee, Arthropathy of Knee Joint | Not applicable | Completed | Ewha Womans University | 300 | 2004-01-01 | 2023-11-09 |
Osteoarthritis, Knee (4) · Arthritis, Rheumatoid (1) · Exsanguination (1) · Osteoarthritis (1) · Pain (1) · Pain, Postoperative (1) · Postoperative Hemorrhage (1) · Postoperative Nausea and Vomiting (1)
Arthritis (5) · Joint Diseases (5) · Musculoskeletal Diseases (5) · Rheumatic Diseases (5) · Osteoarthritis (4) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Postoperative Complications (3) · Neurologic Manifestations (2) · Signs and Symptoms (2) · Autoimmune Diseases (1) · Connective Tissue Diseases (1) · Hemorrhage (1) · Immune System Diseases (1) · Nausea (1)
Arthroplasty, Replacement, Knee (3) · Vancomycin (2) · Analgesics, Opioid (1) · Anesthesia, General (1) · Anesthesia, Spinal (1) · Bupivacaine (1) · Exercise (1) · Saline Solution (1) · Sodium Chloride (1) · Tourniquets (1) · Tranexamic Acid (1) · Tranylcypromine (1)
Chang Gung Memorial Hospital (3) · Mayo Clinic (2) · Ewha Womans University (1) · Kaohsiung Medical University Chung-Ho Memorial Hospital (1) · LifeBridge Health (1) · Mahidol University (1) · Manuel Gomez, MD, MSc. (1) · Northern Orthopaedic Division, Denmark (1) · Okayama University (1) · Ottawa Hospital Research Institute (1) · Riku Antero Palanne (1) · St. Elizabeth Medical Center, Utica, NY (1) · The Cleveland Clinic (1) · Trinity Health Of New England (1) · University of Colorado, Denver (1)
United States (8) · Taiwan (4) · Canada (2) · Denmark (1) · Finland (1) · Japan (1) · Thailand (1)
Andrew B Wickline, MD (1) · Carsten Skarke, MD (1) · Cory L Christiansen, PT, PhD (1) · Geoffrey Dervin, MD,MSc,FRCSC (1) · Hideki Taninishi, MD, PhD (1) · Hsuan-Ti Huang, M.D. (1) · James Nace, MD (1) · Jun-Wen Wang, MD (1) · Keerati Chareancholvanich, MD (1) · Mark J Spangehl (1) · Mark Spangehl, MD (1) · Michael Mont (1) · Sanjay Sinha, MD (1) · Vera Fung, BSc, MSc.PT. (1)
PMID 22898573, PMID 26207975, PMID 30580277, PMID 35091036
K23AG029978 (1), R01HD065900 (1), T32AG000279 (1)