Evaluation of Optimal Dose of Local Anesthetics for Patient Controlled Continuous Femoral Nerve Block

NCT01198340 — Not applicable, Unknown, 60 participants, Okayama University

ClinicalTrials Daily · Areas · Conditions · Drugs · Sponsors ·

Evaluation of Optimal Dose of Local Anesthetics for Patient Controlled Continuous Femoral Nerve Block With Sciatic Nerve Block After Total Knee Arthroplasty

Registry	NCT01198340
Status	Unknown
Phase	Not applicable
Study type	Interventional; randomized, parallel, masking: single, treatment
Enrollment	60 (Estimated)
Sponsor	Okayama University (Other)
Conditions	Arthropathy of Knee Joint
Interventions	PC-FNB with basal administration of local anesthetics, PC-FNB without basal local anesthetics (Procedure)
Dates	start 2010-09-01, primary completion 2012-03-01 (estimated), completion 2012-06-01 (estimated), first posted 2010-09-10, last updated 2011-07-22
Locations	1 site in Japan

-Summary

To evaluate an analgesic effect without basal administration of local anesthetics for patient-controlled femoral nerve block (with sciatic nerve block) after total knee arthroplasty.

Expand all sections · Collapse all

+Arms and interventions

Arm	Type	Interventions	Description
With basal local anesthetics	Active comparator	Procedure: PC-FNB with basal administration of local anesthetics
Without basal local anesthetics	Experimental	Procedure: PC-FNB without basal local anesthetics

PC-FNB with basal administration of local anesthetics (Procedure), also known as PC-FNB with basal ropivacaine administration: Administration of 0.2% ropivacaine for femoral nerve block with 3 ml/h of basal dose, 5ml bolus by the patient, 60 minutes of lock out time.
PC-FNB without basal local anesthetics (Procedure), also known as PC-FAB without basal ropivacaine administration: Administration of 0.2% ropivacaine for femoral nerve block without basal dose, with 8 ml bolus by the patient, 60 minutes of lockout time.

+Outcome measures

Primary outcomes

pain scores by use of numerous rating scale (NRS) [4 days after the surgery]

Secondary outcomes

dose of local anesthetics [4 days after the surgery]

+Eligibility

Sex: All, ages: 20 Years to any

Inclusion Criteria:

* patients older than 20 yrs old scheduled for total knee arthroplasty

Exclusion Criteria:

* none

+Locations (1)

Facility	City	Country	Status
Anesthesiology and Resuscitology, Okayama University Hospital	Okayama, Okayama-ken	Japan	Recruiting

+Investigators

Hideki Taninishi, MD, PhD, Principal investigator, Okayama University