6 completed, 3 unknown, 1 recruiting. 5 Not applicable, 4 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 3, Recruiting 1, Unknown 1 |
| Phase 4 | 4 | Completed 2, Unknown 2 |
| Phase 3 | 1 | Completed 1 |
Follow Exsanguination: new trials by email Literature Review of Exsanguination trials Research Report on Exsanguination
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| REVIVE: Reducing Exsanguination Via In-Vivo Expandable Foam ResQFoam - Hemorrhagic Shock, Trauma | Not applicable | Recruiting | Arsenal Medical, Inc. | 40 | 2025-08-07 | 2025-11-10 |
| Kaolin-based Hemostatic Gauze in Total Knee Arthroplasty Tranexamic acid injection, apply the QCG, apply surgical gauze - Total Blood Loss, Arthropathy of Knee Joint | Phase 4 | Completed | Chang Gung Memorial Hospital | 140 | 2022-03-16 | 2026-07-22 |
| Evaluation of Blood Loss and Pain in TKA With and Without Pneumatic Tourniquet, A Randomized Controlled Trial total knee arthroplasty with and without using pneumatic tourniquet - Total Blood Loss | Not applicable | Unknown | Assiut University | 100 | 2021-12-10 | 2021-12-03 |
| Oral Administration of Tranexamic Acid in Anterior Cruciate Ligament Surgery Reduce Postoperative Haemarthrosis Oral tablet, Placebo - Hemorrhage Postoperative, Anterior Cruciate Ligament Rupture | Phase 4 | Unknown | University of Liege | 104 | 2021-07-06 | 2021-07-28 |
| Noninferiority Oral Tranexamic Acid vs Intravenous Administration in Total Hip Arthroplasty Tranexamic Acid Oral Product, Tranexamic acid injection - Hemorrhage Postoperative, Total Blood Loss | Phase 4 | Completed | University of Liege | 230 | 2021-01-01 | 2022-12-15 |
| Reducing Blood Loss Using Tisseel in TKA Tisseel, Tranexamic Acid - Total Blood Loss | Phase 4 | Unknown | Chang Gung Memorial Hospital | 100 | 2017-11-01 | 2017-10-16 |
| A Transparent Elasticized Adhesive Occlusive Compression Bandage for Use as an Arterial Tourniquet Pneumatic Tourniquet, One Windlass Tourniquet, Two Windlass Tourniquets - Hemorrhage, Vascular Injury | Not applicable | Completed | Marcus Migura | 19 | 2015-12-01 | 2017-08-24 |
| Comparison of Topical Versus Intravenous Tranexamic Acid in TKA normal saline, Tranexamic Acid - Total Blood Loss | Phase 3 | Completed | Shanghai Jiao Tong University School of Medicine | 174 | 2014-07-01 | 2018-04-04 |
| Reduced Total Blood Loss and Blood Transfusion in Non-Septic Revision Knee Arthroplasty Using a Bipolar Sealer Bipolar sealer - Total Blood Loss | Not applicable | Completed | Hvidovre University Hospital | 60 | 2013-10-01 | 2015-08-17 |
| Impact of Fluid Restriction Policy in Reducing the Use of Red Cells in Cardiac Surgery Fluid Restriction Policy, Free fluid infusion - Coronary Artery Disease, Coronary Artery Bypass | Not applicable | Completed | Larissa University Hospital | 192 | 2007-11-01 | 2011-06-07 |
Postoperative Hemorrhage (3) · Hemorrhage (2) · Anterior Cruciate Ligament Injuries (1) · Coronary Artery Disease (1) · Shock, Hemorrhagic (1) · Shock, Traumatic (1) · Vascular System Injuries (1) · Wounds and Injuries (1)
Pathologic Processes (10) · Pathological Conditions, Signs and Symptoms (10) · Hemorrhage (8) · Postoperative Complications (3) · Cardiovascular Diseases (2) · Vascular Diseases (2) · Wounds and Injuries (2) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Coronary Disease (1) · Heart Diseases (1) · Knee Injuries (1) · Leg Injuries (1) · Myocardial Ischemia (1) · Shock (1)
Tranexamic Acid (4) · Arthroplasty, Replacement, Knee (1) · Fibrin Tissue Adhesive (1) · Saline Solution (1) · Sodium Chloride (1) · Tablets (1) · Tranylcypromine (1)
Chang Gung Memorial Hospital (2) · University of Liege (2) · Arsenal Medical, Inc. (1) · Assiut University (1) · Hvidovre University Hospital (1) · Larissa University Hospital (1) · Marcus Migura (1) · Shanghai Jiao Tong University School of Medicine (1)
Belgium (2) · United States (2) · China (1) · Denmark (1) · Greece (1) · Taiwan (1)
Jun-Wen Wang, MD (1) · Marcus W Migura (1) · Mohamed Ahmed Mahran, MD (1) · Timothy Pritts, MD (1)