939 completed, 115 unknown, 89 terminated, 58 recruiting. 1306 Phase 3, 150 Phase 2.
Follow Arthritis: new trials by email Literature Review of Arthritis trials Research Report on Arthritis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of GNSC-001 Intra-articular Injection for Knee Osteoarthritis Gene Therapy GNSC-001, Placebo - Knee Arthritis Osteoarthritis, Knee Arthritis, Osteoarthritis | Phase 2 / Phase 3 | Not yet recruiting | Genascence Corporation | 240 | 2027-07-01 | 2026-09-21 |
| A Study of Zasocitinib in Adults With Psoriatic Arthritis (LATITUDE PsA NeXt) Placebo, Zasocitinib - Psoriatic Arthritis | Phase 3 | Not yet recruiting | Takeda | 644 | 2027-01-11 | 2026-10-27 |
| HTO and Tranexamic Acid Study Tranexamic Acid, Routine medial opening wedge high tibial osteotomy - Osteoarthritis, Knee | Phase 3 | Not yet recruiting | Western University, Canada | 200 | 2027-01-01 | 2026-09-17 |
| Continued Access to Deucravacitinib for Adult SLE/SjD and Pediatric PsO/PsA Study Completers Deucravacitinib - Systemic Lupus Erythematosus, Sjögren's Disease | Phase 3 | Not yet recruiting | Bristol-Myers Squibb | 2300 | 2026-12-31 | 2026-09-03 |
| ACT4RHD is an Open-label, Randomised, Adaptive Platform Trial to Evaluate Novel and Repurposed Clinical Interventions for Patients With Acute Rheumatic Fever and Carditis. ACT4RHD Seeks to Determine Whether These Interventions Reduce RHD Severity at 6 Months. Hydroxychloroquine (HCQ), No Hydroxychloroquine (HCQ), Prednisone or Prednisolone - Rheumatic Fever, Rheumatic Heart Disease in Children | Phase 3 | Not yet recruiting | Starship Child Health, Te Toka Tumai Auckland | 600 | 2026-12-01 | 2026-10-07 |
| A Study to Learn About Berobenatide Given Once Weekly in Adults With Knee Osteoarthritis and Overweight or Obesity With or Without Type 2 Diabetes (VESPER-OA 2) Berobenatide, Placebo - Obesity, Overweight and/or Obesity | Phase 3 | Recruiting | Pfizer | 756 | 2026-10-26 | 2026-11-04 |
| A Study to Learn About Study Medicine Called Berobenatide in Adults With Knee Pain and Overweight or Obesity (VESPER-OA 1) Berobenatide, Placebo - Obesity, Overweight | Phase 3 | Recruiting | Pfizer | 656 | 2026-10-26 | 2026-11-05 |
| the Effect of Ginkgo Biloba on Rheumatoid Arthritis Patients Ginkgo Biloba Extract (120 mg ) manufuctured by EMA PHARM - Rheumatoid Arthritis (RA), Manegmentof Rheumatoid Arthritis | Phase 2 / Phase 3 | Not yet recruiting | Ain Shams University | 50 | 2026-10-15 | 2026-10-06 |
| A Study to Evaluate Efficacy and Safety of a Single Intra-Articular Injection of HL-01 in the Treatment of Pain in Symptomatic Knee Osteoarthritis Sodium hyaluronate solution - 3.36%, Sterile buffered solution - Osteo Arthritis of the Knee | Phase 3 | Not yet recruiting | IBSA Institut Biochimique SA | 704 | 2026-09-30 | 2026-10-07 |
| Intra Articular Injection of Peripheral Blood Mononuclear Cells for Knee Osteoarthritis High-dose PCP-PBMCs injection, Solu-Medrol, Low-dose PCP-PBMCs injection - Knee Osteoarthritis | Phase 2 / Phase 3 | Not yet recruiting | DuoGenic StemCells Corporation (DGSC) | 240 | 2026-09-30 | 2026-07-20 |
| The Effect of Nicorandil on Rheumatoid Arthritis Patients Nicorandil Oral Tablet, Placebo, conventional synthetic antirheumatic drugs (cDMARDs) - Rheumatoid Arthritis (RA) | Phase 2 / Phase 3 | Recruiting | Ain Shams University | 70 | 2026-09-06 | 2026-09-16 |
| Use of Corticosteroid in Intraopertive Injections in Total Knee Replacement Surgery. PAI, PAI + steroid, PAI + zilretta - Knee Osteoarthritis, Musculoskeletal Disease | Phase 2 / Phase 3 | Recruiting | Walter Reed National Military Medical Center | 240 | 2026-09-01 | 2026-08-19 |
| Nicorandil in Atherosclerosis Risk in Patients With Rheumatoid Arthritis Nicorandil 10 MG Oral scored Tablet, DMARD maintenance - Rheumatoid Arthritis (RA, Atherosclerosis | Phase 3 | Not yet recruiting | Tanta University | 46 | 2026-09-01 | 2026-09-11 |
| Research Title: Long Term Functional Outcome of a Single Hyaluronic Acid Injection in Improving Symptoms and Function in Patients With Knee Osteoarthritis - A Single-Arm Open-Label Study (DIART ONE). Hyaluronic Acid (HA) - Osteo Arthritis of the Knee | Phase 3 | Not yet recruiting | Universiti Sains Malaysia | 62 | 2026-08-30 | 2026-07-30 |
| Phase II/III Randomized Trial of UC-MSC Secretome vs Sodium Hyaluronate in Knee Osteoarthritis UC-MSC-Derived Secretome, Sodium Hyaluronate (Hyalein) - Knee Osteoarthritis (Knee OA) | Phase 2 / Phase 3 | Not yet recruiting | Universitas Sriwijaya | 50 | 2026-08-30 | 2026-05-12 |
| Bone Marrow Aspirate Concentrate Versus Triamcinolone Injection For Hip Osteoarthritis Aspire Needle + Emcyte PureBMC, Triamcinolone - Hip Osteoarthritis | Phase 3 | Recruiting | The Cleveland Clinic | 100 | 2026-08-28 | 2026-09-09 |
| A Study of Econoglutide Injection in Obese Participants With Knee Osteoarthritis (KOA) Ecnoglutide Injection, placebo with matching volume - Knee Osteoarthritis, Obesity | Phase 3 | Recruiting | Hangzhou Sciwind Biosciences Co., Ltd. | 360 | 2026-08-03 | 2026-08-31 |
| Two Arm, Double-blind, Phase III Study Assessing Efficacy and Safety of Ianalumab Versus Placebo, in Participants With Sjögren's Disease With High Symptom Burden VAY736, Placebo - Sjögren´s Disease | Phase 3 | Recruiting | Novartis Pharmaceuticals | 570 | 2026-07-16 | 2026-11-09 |
| A Trial of Ribupatide Injection in Participants With Obesity and Knee Osteoarthritis Ribupatide Injection, Placebo - Participants With Obesity and Knee Osteoarthritis | Phase 3 | Not yet recruiting | Fujian Shengdi Pharmaceutical Co., Ltd. | 382 | 2026-07-01 | 2026-07-17 |
| Tru-Vu Wrist Positioning Aid Multi-Center Implementation Within NLHS Tru Vu tool and training - Trauma (Including Fractures), Arthritis | Phase 3 | Not yet recruiting | Western University | 1800 | 2026-06-14 | 2026-05-18 |
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Arthritis, Rheumatoid (451) · Osteoarthritis (321) · Osteoarthritis, Knee (259) · Arthritis, Psoriatic (105) · Spondylitis, Ankylosing (82) · Arthritis, Juvenile (79) · Pain (69) · Gout (46) · Osteoarthritis, Hip (45) · Joint Diseases (32) · Axial Spondyloarthritis (26) · Musculoskeletal Diseases (26) · Sjogren's Syndrome (26) · Chronic Pain (24)
Musculoskeletal Diseases (1280) · Joint Diseases (1274) · Rheumatic Diseases (1065) · Skin and Connective Tissue Diseases (674) · Connective Tissue Diseases (567) · Immune System Diseases (557) · Autoimmune Diseases (547) · Bone Diseases (213) · Spinal Diseases (204) · Spondylitis (202) · Spondylarthropathies (193) · Spondylarthritis (191) · Pathological Conditions, Signs and Symptoms (178) · Osteoarthritis (175)
Methotrexate (119) · tocilizumab (90) · Adalimumab (77) · Etanercept (47) · Abatacept (37) · Certolizumab Pegol (36) · Infliximab (35) · secukinumab (34) · Celecoxib (31) · Rituximab (31) · golimumab (30) · Sodium Chloride (29) · tofacitinib (28) · Hyaluronic Acid (21) · Naproxen (20)
Hoffmann-La Roche (76) · Pfizer (53) · Novartis Pharmaceuticals (51) · Amgen (36) · Eli Lilly and Company (32) · Bristol-Myers Squibb (30) · Abbott (28) · Janssen Research & Development, LLC (26) · AbbVie (17) · Centocor, Inc. (16) · Novartis (16) · UCB Pharma (14) · UCB Biopharma SRL (12) · Assistance Publique - Hôpitaux de Paris (11) · Boehringer Ingelheim (11)
United States (526) · Germany (287) · Poland (256) · Canada (249) · Spain (239) · United Kingdom (211) · France (199) · Russia (186) · Czechia (180) · Australia (174) · Hungary (170) · Italy (170) · Mexico (162) · Belgium (158) · South Korea (147)
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