27 active not recruiting. 27 Phase 2, 9 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 27 | Active not recruiting 27 |
| Phase 1 | 9 | Active not recruiting 9 |
| Phase 3 | 3 | Active not recruiting 3 |
Follow Arthritis: new trials by email Literature Review of Arthritis trials Research Report on Arthritis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pre-emptive Insulin to Prevent High Glucose After a Knee Steroid Injection in Adults With Type 2 Diabetes Insulin Isophane Human, NPH, Pre-emptive Algorithm, Triamcinolone Acetonide Knee Injection - Diabetes Mellitus, Type 2, Hyperglycemia Due to Type 2 Diabetes Mellitus | Phase 1 / Phase 2 | Active not recruiting | Shifa International Hospital | 125 | 2026-08-10 | 2026-09-15 |
| Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015) Tulisokibart, Placebo - Psoriatic Arthritis | Phase 2 | Active not recruiting | Merck Sharp & Dohme LLC | 140 | 2026-04-20 | 2026-10-20 |
| Single vs Triple Hyaluronic Acid in Knee Osteoarthritis Three intra-articular hyaluronic acid (HA) injections, One intra-articular hyaluronic acid (HA) injection - Osteoarthritis, Knee | Phase 2 / Phase 3 | Active not recruiting | University of Erlangen-Nürnberg Medical School | 46 | 2026-01-15 | 2026-05-14 |
| A Study to Evaluate the Efficacy and Safety of JNJ-88545223 for the Treatment of Participants With Active Psoriatic Arthritis JNJ-88545223, Placebo - Arthritis, Psoriatic | Phase 2 | Active not recruiting | Janssen Research & Development, LLC | 157 | 2026-01-15 | 2026-11-03 |
| Evaluation of Efficacy and Safety of AR882 and XOI Co-administration in Uricase Treatment Failed Patients AR882 75 mg, XOI Low Dose, XOI High Dose - Gout, Gouty Arthritis | Phase 2 | Active not recruiting | Arthrosi Therapeutics | 15 | 2025-12-03 | 2026-05-15 |
| Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR) Somatropin (recombinant human growth hormone), bacteriostatic saline placebo - Knee Osteoarthritis (Knee OA), Knee Osteoarthritis (OA) | Phase 1 / Phase 2 | Active not recruiting | Dr. David Wasserstein | 34 | 2025-10-31 | 2026-07-31 |
| A Clinical Study of Tulisokibart (MK-7240) to Treat Rheumatoid Arthritis (RA) (MK-7240-014) Tulisokibart, Placebo, Methotrexate - Arthritis, Rheumatoid | Phase 2 | Active not recruiting | Merck Sharp & Dohme LLC | 185 | 2025-10-08 | 2026-09-24 |
| ASKC200 for Knee Osteoarthritis Pain 5% ASKC200, 1% Diclofenac Diethylamine Emulgel, Placebo - Osteoarthritis (OA) of the Knee, Pain | Phase 2 | Active not recruiting | Jiangsu Aosaikang Pharmaceutical Co., Ltd. | 175 | 2025-09-12 | 2026-08-03 |
| A Study of SPY072 in Rheumatic Disease SPY002-072, Placebo - Rheumatoid Arthritis, Psoriatic Arthritis | Phase 2 | Active not recruiting | Spyre Therapeutics, Inc. | 285 | 2025-08-21 | 2026-06-05 |
| A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's Disease Rapcabtagene autoleucel - Rheumatoid Arthritis (RA) and Sjögren's Disease (SjD) | Phase 1 / Phase 2 | Active not recruiting | Novartis Pharmaceuticals | 27 | 2025-06-20 | 2026-09-04 |
| 53-Week Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 With Mild to Severe Tibio-Femoral Osteoarthritis of the Knee TPX-100 200mg, Once weekly for 4 weeks, PBS - Osteoarthritis (OA) of the Knee | Phase 2 | Active not recruiting | OrthoTrophix, Inc | 270 | 2025-05-09 | 2026-02-17 |
| A Study to Evaluate the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Participants With Active, Difficult to Treat Rheumatoid Arthritis IMVT-1402, Placebo - Rheumatoid Arthritis | Phase 2 | Active not recruiting | Immunovant Sciences GmbH | 120 | 2025-01-10 | 2026-04-22 |
| Comparison of B-cell Depletion by Rituximab and Anti-CD 19 CAR-T Therapy in Patients With Rheumatoid Arthritis KYV101, Rituximab (active comparator) - Rheumatoid Arthritis | Phase 1 / Phase 2 | Active not recruiting | Charite University, Berlin, Germany | 13 | 2024-12-04 | 2026-03-05 |
| Two-period Crossover Study to Demonstrate the Comparability of Pharmacokinetics of Subcutaneous Ianalumab Between 2mL Auto-injector/2mL PFS with1mL Pre-filled Syringe in Adult Participants With Autoimmune Disease VAY736 1ml PFS, VAY736 2 ml PFS, VAY736 2ml AI - Sjögrens Disease, Systemic Lupus Erythematosus | Phase 2 | Active not recruiting | Novartis Pharmaceuticals | 155 | 2024-07-02 | 2026-10-14 |
| Intra-articular Allocetra in Osteoarthritis of the 1st Carpo-metacarpal Joint Allocetra - Safety run-in phase, Placebo, Allocetra - Randomization phase - Osteoarthritis Thumb | Phase 1 / Phase 2 | Active not recruiting | Kaplan Medical Center | 46 | 2024-06-10 | 2026-04-13 |
| Platelet Rich Plasma Injections In Young And Old Human Subjects Platelet-Rich Plasma (PRP) Injections, Centrifuge, Control saline injection - Osteoarthritis, Articular Cartilage | Phase 2 | Active not recruiting | University of California, San Francisco | 60 | 2024-06-01 | 2026-09-08 |
| PK and Safety Evaluation Study of SAP-001 in Adult Subjects With Normal and Impaired Renal Function SAP-001 - Gout, Hyperuricemia | Phase 1 / Phase 2 | Active not recruiting | Shanton Pharma Pte. Ltd. | 32 | 2024-04-24 | 2024-12-11 |
| Effectivity of Allogenic Umbilical Cord Mesenchymal Stem Cells Conditioned Media for Osteoarthritis of the Knee Joint Intra-articular secretome injection therapy - Osteoarthritis Knee | Phase 1 / Phase 2 | Active not recruiting | Kementerian Riset dan Teknologi / Badan Riset dan Inovasi Nasional, Indonesia | 11 | 2024-04-03 | 2024-11-15 |
| A Study of Efficacy and Safety of Rosnilimab in Subjects with Moderate to Severe Rheumatoid Arthritis (RENOIR) Rosnilimab, Placebo - Rheumatoid Arthritis | Phase 2 | Active not recruiting | AnaptysBio, Inc. | 420 | 2023-08-31 | 2024-11-25 |
| Evaluation Safety and Explore Efficacy Long-term Follow-up Study on Subjects Receiving SMUP-IA-01 or Active Control SMUP-IA-01(low-dose), SMUP-IA-01(mid-dose), High Hyal Plus - Knee Osteoarthritis | Phase 2 | Active not recruiting | Medipost Co Ltd. | 84 | 2023-03-20 | 2025-02-07 |
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Arthritis, Rheumatoid (8) · Osteoarthritis, Knee (8) · Osteoarthritis (6) · Arthritis, Psoriatic (3) · Gout (3) · Hyperuricemia (3) · Autoimmune Diseases (2) · Axial Spondyloarthritis (2) · Arthritis, Gouty (1) · Collagen Diseases (1) · Diabetes Mellitus, Type 2 (1) · Inflammation (1) · Lupus Erythematosus, Systemic (1) · Musculoskeletal Diseases (1) · Pain (1)
Joint Diseases (27) · Musculoskeletal Diseases (26) · Rheumatic Diseases (23) · Skin and Connective Tissue Diseases (11) · Connective Tissue Diseases (9) · Immune System Diseases (9) · Autoimmune Diseases (7) · Osteoarthritis (6) · Pathological Conditions, Signs and Symptoms (5) · Bone Diseases (4) · Metabolic Diseases (4) · Nutritional and Metabolic Diseases (4) · Pathologic Processes (4) · Spinal Diseases (4)
Injections (2) · Colchicine (1) · Growth Hormone (1) · Human Growth Hormone (1) · Insulin, Isophane (1) · Isophane Insulin, Human (1) · Methotrexate (1) · Pentosan Sulfuric Polyester (1) · Prolactin-Releasing Hormone (1) · Rituximab (1) · Sodium Chloride (1) · ianalumab (1) · tofacitinib (1)
Merck Sharp & Dohme LLC (2) · Novartis Pharmaceuticals (2) · Shanton Pharma Pte. Ltd. (2) · AnaptysBio, Inc. (1) · Arthrosi Therapeutics (1) · Beijing Baylx Biotech Co., Ltd. (1) · Biocad (1) · Bioventus LLC (1) · Charite University, Berlin, Germany (1) · Dr. David Wasserstein (1) · Immunovant Sciences GmbH (1) · Janssen Research & Development, LLC (1) · Jiangsu Aosaikang Pharmaceutical Co., Ltd. (1) · Kaplan Medical Center (1) · Kementerian Riset dan Teknologi / Badan Riset dan Inovasi Nasional, Indonesia (1)
United States (15) · Germany (8) · Spain (8) · Poland (7) · Canada (6) · China (4) · Czechia (4) · Hungary (4) · Georgia (3) · South Korea (3) · Ukraine (3) · United Kingdom (3) · Argentina (2) · Australia (2) · Bulgaria (2)
Anthony Luke, MD, MPH (1) · Bintang S Bintang Soetjahjo, MD, PhD (1) · Blake M Warner, D.D.S. (1) · Carmen Arencibia (1) · David Simon, Professor Dr. med. (1) · Dr. David Wasserstein (1) · Moin Khan, MD (1) · Robert Keenan, MD (1) · Saima Abbass, MD, PhD (1) · Simon von Stengel, PhD (1)
PMID 39704612, PMID 41638751, PMID 42661098
2025 (3), 2023 (1)