6 completed, 3 recruiting, 2 active not recruiting, 2 terminated. 5 Phase 2, 4 Not applicable, 4 Phase 3, 1 Phase 4.
Follow this drug Literature Review of Pentosan Sulfuric Polyester trials Research Report on Pentosan Sulfuric Polyester
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of a High-resolution Program for the Prevention of Suicidal Behavior in At-risk Adults: a Quasi-experimental Ambispective Cohort Study PPS; SUICIDE PREVENTION PROGRAM - Prevention of Suicidal Behavior | Not applicable | Recruiting | University of Salamanca | 198 | 2025-05-01 | 2026-06-18 |
| Treatment and Duration Effect of Pentosan Polysulfate Sodium (PPS) in Participants With Knee Osteoarthritis Pain Pentosan Polysulphate Sodium, Placebo (Sodium Chloride Injection, 0.9%) - Osteoarthritis, Knee | Completed | Paradigm Biopharmaceuticals Ltd. | 133 | 2023-06-24 | 2025-07-22 | |
| Inhibitory Effect of a Polyphenol Supplement on Dietary Iron Absorption in Adults with Thalassemia Meal matrix with polyphenol supplement (PPS), Meal matrix with placebo, No meal matrix with PPS - Thalassemia, Iron Overload | Not applicable | Completed | Swiss Federal Institute of Technology | 20 | 2022-06-01 | 2025-03-05 |
| Radiation Cystitis Treated With Pentosan Polysulfate Sodium Trial Pentosan Polysulfate Sodium 100 MG Oral Capsule, Placebo - Radiation Cystitis | Phase 2 / Phase 3 | Recruiting | National Taiwan University Hospital | 72 | 2022-04-29 | 2022-05-04 |
| Treatment Effects of Subcutaneous Injections of Pentosan Polysulfate Sodium vs Placebo in Participants With Knee OA Pain Pentosan Polysulfate Sodium twice weekly, Placebo (Sodium Chloride Injection, 0.9%), Pentosan Polysulfate Sodium Fixed Dose - Osteoarthritis, Knee | Phase 2 / Phase 3 | Active not recruiting | Paradigm Biopharmaceuticals USA (INC) | 602 | 2021-10-19 | 2024-04-08 |
| Evaluate the Efficacy and Safety of U101 Oral Capsules in the Prevention of Uncomplicated rUTIs in Women U101, Placebo - Recurrent Urinary Tract Infections in Women | Phase 3 | Recruiting | TCM Biotech International Corp. | 348 | 2020-10-14 | 2026-10-02 |
| Prevention and Management of Intravesical BCG-related Lower Urinary Tract Symptoms Pentosan Polysulfate Na 100Mg Cap, Placebo oral capsule - Lower Urinary Tract Symptoms, Bladder Carcinoma | Phase 2 | Terminated | Sir Mortimer B. Davis - Jewish General Hospital | 3 | 2019-05-03 | 2022-03-04 |
| Pentosan Polysulfate Treatment's Effectiveness Pentosan Polysulphate - Chronic Interstitial Cystitis | Not applicable | Completed | Hisar Intercontinental Hospital | 37 | 2018-01-01 | 2025-05-22 |
| Pentosan Polysulfate Sodium and Meclofenamic Acid as Treatments in Patients With Psychotic Disorders Meclofenamic acid, Pentosan polysulfate sodium - Psychotic Disorders, Schizophrenia | Phase 2 | Completed | The University of Texas Health Science Center, Houston | 8 | 2015-08-07 | 2019-03-26 |
| A 3-Arm Study on G7 Acetabular Cup With Echo BiMetric Stem in Total Hip Arthroplasty Hip Arthroplasty - Osteoarthrosis, Pain | Not applicable | Active not recruiting | Zimmer Biomet | 360 | 2015-05-04 | 2025-11-25 |
| Effectiveness and Safety Study of Pentosan Polysulfate Sodium for the Treatment of Interstitial Cystitis Pentosan polysulfate sodium 100 mg, Placebo - Interstitial Cystitis | Phase 4 | Terminated | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 369 | 2003-09-01 | 2014-04-21 |
| Pentosan Polysulfate in Treating Patients With Gastrointestinal Disturbance Caused by Radiation Therapy pentosan polysulfate sodium, quality-of-life assessment - Diarrhea, Radiation Enteritis | Phase 3 | Completed | Radiation Therapy Oncology Group | 174 | 1999-06-01 | 2020-10-19 |
| An Effectiveness and Safety Study of ELMIRON (Pentosan Polysulfate Sodium) for the Treatment of Chronic Non-Bacterial Inflammation of the Prostate Gland pentosan polysulfate sodium - Prostatitis | Phase 2 | Completed | McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. | 283 | 2011-07-01 |
Osteoarthritis (3) · Cystitis, Interstitial (2) · Osteoarthritis, Knee (2) · Arthritis (1) · Bipolar Disorder (1) · Diarrhea (1) · Iron Overload (1) · Lower Urinary Tract Symptoms (1) · Mental Disorders (1) · Non-Muscle Invasive Bladder Neoplasms (1) · Pain (1) · Prostatitis (1) · Psychotic Disorders (1) · Schizophrenia (1) · Suicidal Ideation (1)
Hisar Intercontinental Hospital (1) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (1) · McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. (1) · National Taiwan University Hospital (1) · Paradigm Biopharmaceuticals Ltd. (1) · Paradigm Biopharmaceuticals USA (INC) (1) · Radiation Therapy Oncology Group (1) · Sir Mortimer B. Davis - Jewish General Hospital (1) · Swiss Federal Institute of Technology (1) · TCM Biotech International Corp. (1) · The University of Texas Health Science Center, Houston (1) · University of Salamanca (1) · Zimmer Biomet (1)
United States (5) · Canada (3) · Australia (2) · Taiwan (2) · Denmark (1) · Finland (1) · Spain (1) · Sweden (1) · Thailand (1) · Turkey (Türkiye) (1)
Thomas Schnitzer (2) · Anders Troelsen, MD, PhD (1) · Chao-Yuan Huang, MD, PhD (1) · En Meng, MD (1) · Henrik Malchau, MD, PhD (1) · Lysanne Campeau, MD, PhD (1) · Michael B Zimmermann, MD, PhD (1) · Miljenko V. Pilepich, MD (1) · Ville Remes, MD, PhD (1)