534 completed, 99 unknown, 80 recruiting, 48 terminated. 847 Phase 1, 219 Phase 2.
Follow Arthritis: new trials by email Literature Review of Arthritis trials Research Report on Arthritis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cannabichromene Safety in Rheumatoid Arthritis Cannabichromene - Arthritis, Rheumatoid | Phase 1 / Phase 2 | Withdrawn | Crystal Lederhos Smith | 2028-07-15 | 2026-09-23 | |
| Pilot and Feasibility Study of Anti-CD14 for the Treatment of Knee Osteoarthritis Atibuclimab, saline placebo - Knee Osteoarthritis (Knee OA) | Phase 1 | Not yet recruiting | VA Office of Research and Development | 40 | 2027-01-01 | 2026-07-15 |
| Evaluation of Superiority of Valsartan+Celecoxib+Metformin Over Metformin Alone in Type 2 Diabetes Patients Metformin, Val, Cel and Met XR Low, Val, Cel and Met XR High - Type 2 Diabetes, High Blood Pressure | Phase 1 / Phase 2 | Withdrawn | ARKAY Therapeutics | 2026-12-10 | 2026-07-16 | |
| Study Investigating the Safety of Anti-CD19 CAR-T Cells Therapy Produced at Gustave Roussy for Adults With Severe and Refractory Systemic Autoimmune Rheumatic Diseases anti-CD19 CAR-T cells - Rheumatoid Arthritis (RA), Systemic Lupus Erythematosus (SLE) | Phase 1 | Not yet recruiting | Gustave Roussy, Cancer Campus, Grand Paris | 6 | 2026-12-01 | 2026-09-02 |
| Safety and Tolerability of a Single Intravenous Infusion of BX-U001 in Refractory Rheumatoid Arthritis hUC-MSC suspension, Placebo - Rheumatoid Arthritis | Phase 1 | Not yet recruiting | Baylx Inc. | 16 | 2026-12-01 | 2025-12-23 |
| Phase Ia Study of MST-931 in Healthy Adult Subjects MST-931, MST-931 Placebo - Ankylosing Spondylitis (AS) | Phase 1 | Not yet recruiting | Mabsoft Therapeutics (Shanghai) Co., Ltd. | 32 | 2026-11-30 | 2026-10-29 |
| A Study to Learn About a Medicine Called PF-08154225 in Participants With Autoimmune Diseases PF-08154225 - Systemic Lupus Erythematosus, Rheumatoid Arthritis | Phase 1 / Phase 2 | Not yet recruiting | Pfizer | 54 | 2026-11-19 | 2026-10-01 |
| A Study Evaluating the Safety, Tolerability, and Activity of ICM-203 in Subjects With Knee Osteoarthritis. ICM-203 - Osteoarthritis, Knee | Phase 1 / Phase 2 | Withdrawn | ICM Co. Ltd. | 2026-11-15 | 2026-09-08 | |
| Safety and Efficacy of Universal CAR-T Cells (UWD-CD19) Combined With Immunosuppressants in the Treatment of Refractory Autoimmune Diseases anti-CD19 CAR-T cells - Systemic Lupus Erthematosus, Systemic Sclerosis (SSc) | Phase 1 / Phase 2 | Not yet recruiting | Peking University Third Hospital | 9 | 2026-11-01 | 2026-09-23 |
| R-2487 in Patients With Sjogren's Syndrome (SS) R-2487 - Sjogren's Syndrome, Sjögren | Phase 1 | Not yet recruiting | Rise Therapeutics LLC | 36 | 2026-11-01 | 2026-09-28 |
| A Study of BMS-986553 in Participants With Refractory Autoimmune Diseases BMS-986553 - Systemic Lupus Erythematosus, Sjögren's Disease | Phase 1 | Not yet recruiting | Bristol-Myers Squibb | 60 | 2026-10-30 | 2026-10-14 |
| Efficacy and Safety of Dapagliflozin as an Adjunct to Conventional Disease-Modifying Antirheumatic Drugs in Patients With Rheumatoid Arthritis Placebo, Dapagliflozin (10mg Tab) - Rheumatoid Arthritis (RA | Phase 1 / Phase 2 | Not yet recruiting | Tanta University | 100 | 2026-10-30 | 2026-10-28 |
| A Study of BMS-986528 in Participants With Refractory Rheumatoid Arthritis BMS-986528 - Arthritis, Rheumatoid | Phase 1 / Phase 2 | Recruiting | Bristol-Myers Squibb | 84 | 2026-10-06 | 2026-10-23 |
| BAFF CAR-T Cells (LMY-922) for Treatment of Refractory Autoimmune Disease LMY-922 - Rheumatoid Arthritis (RA), Systemic Lupus Erthematosus (SLE) | Phase 1 | Not yet recruiting | Luminary Therapeutics | 94 | 2026-10-01 | 2026-07-28 |
| NANOVAE to Treat Knee Osteoarthritis (KOA) NANOVAE - Acellular Allogenic Human Amniotic Fluid (hAF), 0.9% Sodium Chloride Injection, USP - Knee Osteoarthritis | Phase 1 / Phase 2 | Not yet recruiting | Nova Vita Laboratory | 24 | 2026-10-01 | 2026-04-13 |
| FT839 in Autoimmune Diseases FT839 - ANCA-Associated Vasculitis (AAV), Idiopathic Inflammatory Myositis (IIM) | Phase 1 / Phase 2 | Recruiting | Fate Therapeutics | 446 | 2026-10-01 | 2026-09-02 |
| A Study of ATG-201 in Adult Participants With Autoimmune Diseases ATG-201 - Systemic Lupus Erythematosus, Systemic Sclerosis (SSc) | Phase 1 | Recruiting | Antengene Biologics Limited | 149 | 2026-09-26 | 2026-10-28 |
| A Trial in Healthy Adult Participants and Adults With Autoimmune Disease to Test How HBM7020 is Tolerated and Absorbed in the Body HBM7020 - Rheumatoid Arthritis, Systemic Lupus Erythematosus | Phase 1 | Recruiting | Otsuka Pharmaceutical Development & Commercialization, Inc. | 63 | 2026-09-24 | 2026-10-13 |
| Radiation to Treat Joint Damage Caused by Cancer Immunotherapy Low dose radiation therapy - Arthritis, Arthropathy | Phase 1 | Not yet recruiting | University of Chicago | 20 | 2026-08-26 | 2026-03-23 |
| A Study to Evaluate Pharmacokinetics of DRL_AB in Healthy Male Participants DRL_AB - Healthy Volunteers | Phase 1 | Not yet recruiting | Dr. Reddy's Laboratories Limited | 160 | 2026-08-19 | 2026-08-04 |
Showing 20 of 847. Sign in to see all of them.
Arthritis, Rheumatoid (383) · Osteoarthritis (175) · Osteoarthritis, Knee (171) · Gout (56) · Lupus Erythematosus, Systemic (48) · Sjogren's Syndrome (43) · Arthritis, Psoriatic (30) · Hyperuricemia (28) · Autoimmune Diseases (27) · Scleroderma, Systemic (27) · Arthritis, Juvenile (24) · Myositis (22) · Inflammation (21) · Pain (21)
Musculoskeletal Diseases (836) · Joint Diseases (835) · Rheumatic Diseases (777) · Skin and Connective Tissue Diseases (472) · Connective Tissue Diseases (449) · Immune System Diseases (446) · Autoimmune Diseases (422) · Osteoarthritis (115) · Pathological Conditions, Signs and Symptoms (103) · Skin Diseases (75) · Nutritional and Metabolic Diseases (72) · Metabolic Diseases (67) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (65) · Genetic Diseases, Inborn (65)
Methotrexate (27) · Rituximab (17) · tocilizumab (14) · Naproxen (13) · Abatacept (12) · sarilumab (11) · Hyaluronic Acid (9) · tofacitinib (9) · Saline Solution (8) · Sodium Chloride (8) · Cyclophosphamide (7) · Midazolam (7) · fostamatinib (7) · Etanercept (6) · Ibuprofen (6)
Bristol-Myers Squibb (26) · Pfizer (25) · AstraZeneca (23) · GlaxoSmithKline (18) · Jiangsu HengRui Medicine Co., Ltd. (13) · Sanofi (13) · Eli Lilly and Company (11) · Amgen (10) · Novartis Pharmaceuticals (10) · Ardea Biosciences, Inc. (8) · Hoffmann-La Roche (8) · Novo Nordisk A/S (8) · LG Chem (7) · Mayo Clinic (7) · Regeneron Pharmaceuticals (7)
United States (322) · China (105) · Germany (74) · United Kingdom (53) · Australia (50) · Spain (42) · South Korea (39) · Poland (35) · Canada (33) · Netherlands (33) · France (27) · Belgium (23) · Japan (20) · Russia (20) · Hungary (17)
Alison Heald, MD (4) · Hamid Gourabi, PhD (4)
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