19 completed, 8 unknown, 1 not yet recruiting, 1 recruiting. 6 Phase 3, 2 Not applicable, 2 Phase 1, 2 Phase 2, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 4, Not yet recruiting 1, Recruiting 1 |
| Not applicable | 2 | Completed 2 |
| Phase 1 | 2 | Completed 2 |
| Phase 2 | 2 | Completed 2 |
| Phase 4 | 2 | Completed 1, Unknown 1 |
Follow Amebiasis: new trials by email Literature Review of Amebiasis trials Research Report on Amebiasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Diloxanide Furoate as Additional Luminal Agent Along With Metronidazole for the Treatment of Amoebic Liver Abscess Diloxanide furoate, Placebo - Liver Abscess, Amoebic Liver Abscess | Phase 3 | Not yet recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 220 | 2026-09-04 | 2026-09-10 |
| Retrospective Chart Review of Patients With Acanthamoeba Keratitis Who Have Received 0.8 mg/mL Polihexanide as Part of the "Medicines in Special Situations" (Medicamentos en Situaciones Especiales) Program in Spain. PHMB 0.08% - Acanthamoeba Keratitis | Completed | SIFI SpA | 23 | 2025-10-30 | 2026-06-22 | |
| Blastocystis and Cryptosporidium Infection in Colorectal Cancer Patients ELISA / PCR - Blastocystis Infection, Cryptosporidium Infection | Unknown | Assiut University | 54 | 2024-11-01 | 2024-04-23 | |
| Retrospective Chart Review of Patients With Acanthamoeba Keratitis Who Have Received 0.8 mg/ml Polihexanide Acanthamoeba Keratitis | Completed | SIFI SpA | 40 | 2024-09-30 | 2025-10-01 | |
| Parasitic Ulcer Treatment Trial Polyhexamethylene biguanide (PHMB), Topical corticosteroid, Topical placebo - Acanthamoeba Keratitis | Phase 3 | Recruiting | Jeremy Keenan, MD, MPH | 232 | 2024-07-01 | 2026-10-01 |
| Acanthamoeba and Artificial Intelligence Acanthamoeba Keratitis, Artificial Intelligence | Unknown | IRCCS Ospedale San Raffaele | 151 | 2024-05-01 | 2024-05-10 | |
| Isolation and Characterization of Blastocystis Hominis as Apotential Human Pathogen culture and PCR - Blastocystis Hominis Infections | Unknown | Assiut University | 72 | 2023-12-01 | 2023-04-18 | |
| Efficacy of Calprotectin as A Marker For the Pathogenicity of Blastocystis Infection Fecal Calprotectin ELISA kit - Blastocystis Infections | Unknown | Sohag University | 150 | 2023-03-01 | 2023-02-13 | |
| Molecular Characterization of Blastocystis Isolates From Human by Restriction Fragment Length Polymorphism (RFLP) Analysis RFLP analysis of SSU rRNA - Blastocystis Infections | Unknown | Sohag University | 100 | 2022-11-01 | 2022-10-14 | |
| Rose Bengal Electromagnetic Activation With Green Light for Infection Reduction Moxifloxacin Ophthalmic, Chlorhexidine Gluconate, Natamycin - Acanthamoeba Keratitis, Fungal Keratitis | Phase 3 | Completed | University of California, San Francisco | 330 | 2022-08-03 | 2026-09-03 |
| Immunochromatography Versus Microscopy for Diagnosis of Entamoeba Histolytica/Dispar Infection. Dysentery Amebic | Unknown | Sohag University | 100 | 2021-03-20 | 2021-10-12 | |
| Parasitic Ulcer Treatment Trial Pilot Chlorhexidine, Povidone-Iodine, Prednisolone Sodium Phosphate - Acanthamoeba Keratitis | Phase 2 | Completed | University of California, San Francisco | 49 | 2018-01-01 | 2026-05-07 |
| Polihexanide (PHMB) Eye Drops in Patients Affected by Acanthamoeba Keratitis PHMB 0.08%, Propamidine 0.1%, placebo - Acanthamoeba Keratitis | Phase 3 | Completed | SIFI SpA | 135 | 2017-08-13 | 2023-08-22 |
| Ultrahigh-resolution Optical Coherence Tomography Imaging of the Anterior Eye Segment Structures Ultrahigh resolution Spectral Domain OCT - Meibomian Gland Dysfunction, Cataract | Not applicable | Completed | Medical University of Vienna | 14 | 2017-07-12 | 2025-05-23 |
| Auranofin for Giardia Protozoa Auranofin, Placebo - Amoebic Dysentery, Giardiasis | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 93 | 2016-11-06 | 2023-01-26 |
| Primary Cecal Pathologies Presenting as Acute Abdomen Operated - Acute Abdomen, Emergency Surgery | Completed | Jawaharlal Nehru Medical College | 43 | 2016-01-01 | 2017-08-25 | |
| Safety and Tolerability of Preservative-free Polyhexamethylene Biguanide (PHMB) Ophthalmic Solution in Healthy Subjects 0.04% PHMB, 0.06% PHMB, 0.08% PHMB - Acanthamoeba Keratitis | Phase 1 | Completed | SIFI SpA | 90 | 2015-11-01 | 2017-02-09 |
| Ameparomo Capsules 250 mg Drug Use Investigation Intestinal Amebiasis | Completed | Pfizer | 120 | 2015-10-19 | 2020-12-09 | |
| Anaemetro I.V. Infusion 500mg Drug Use Investigation Anaerobic Infection, Infectious Enterocolitis | Completed | Pfizer | 107 | 2015-07-01 | 2018-12-28 | |
| Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders Stool culturing for pathogenic bacteria, Kato-Katz technique, Baermann technique - Soil-transmitted Helminthiasis, Schistosomiasis | Completed | Swiss Tropical & Public Health Institute | 2800 | 2014-07-01 | 2016-10-25 |
Showing 20 of 30. Sign in to see all of them.
Acanthamoeba Keratitis (10) · Blastocystis Infections (5) · Dysentery, Amebic (4) · Giardiasis (3) · Liver Abscess, Amebic (3) · Colorectal Neoplasms (2) · Cryptosporidiosis (2) · Diarrhea (2) · Abdomen, Acute (1) · Abdominal Pain (1) · Aniridia (1) · Brucellosis (1) · Campylobacter Infections (1) · Cataract (1)
Infections (30) · Protozoan Infections (30) · Parasitic Diseases (29) · Digestive System Diseases (15) · Gastrointestinal Diseases (12) · Intestinal Diseases (12) · Corneal Diseases (10) · Eye Diseases (10) · Eye Infections (10) · Eye Infections, Parasitic (10) · Intestinal Diseases, Parasitic (10) · Keratitis (9) · Gastroenteritis (6) · Dysentery (5)
polihexanide (3) · Auranofin (2) · nitazoxanide (2) · Adrenal Cortex Hormones (1) · Chlorhexidine (1) · Corneal Cross-Linking (1) · Hypromellose Derivatives (1) · Mebendazole (1) · Metronidazole (1) · Multiplex Polymerase Chain Reaction (1) · Natamycin (1) · Povidone-Iodine (1) · Rose Bengal (1) · chlorhexidine gluconate (1) · dibrompropamidine (1)
SIFI SpA (4) · National Institute of Allergy and Infectious Diseases (NIAID) (3) · Sohag University (3) · Assiut University (2) · Pfizer (2) · Romark Laboratories L.C. (2) · University of California, San Francisco (2) · IRCCS Ospedale San Raffaele (1) · Janssen-Cilag Ltd. (1) · Jawaharlal Nehru Medical College (1) · Jeremy Keenan, MD, MPH (1) · Medical University of Vienna (1) · National Taiwan University Hospital (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · Swiss Tropical & Public Health Institute (1)
India (4) · Egypt (3) · United States (3) · Bangladesh (2) · Brazil (2) · Italy (2) · Mexico (2) · Nepal (2) · United Kingdom (2) · Austria (1) · Cambodia (1) · Côte d’Ivoire (1) · Democratic Republic of the Congo (1) · Indonesia (1) · Mali (1)
Samir M Kabil, MD (2) · Yehia El-Gohary, MD (2) · Gerami Seitzman, MD (1) · Jennifer Rose-Nussbaumer, MD (1) · Jeremy D Keenan, MD (1) · Jeremy Keenan, MD, MPH (1) · John Dart, MD (1) · Karl Knutsson, MD (1) · Katja Polman, PhD (1) · Kaushal D Singh, MS Surgery (1)
PMID 26282537, PMID 27812090, PMID 27821451, PMID 28327104, PMID 30074085, PMID 33239413, PMID 35491421, PMID 37802392, PMID 39011096, PMID 39192339, PMID 41561665, PMID 41914638, PMID 42141248, PMID 42348235
UG1EY028518 (1), UG1EY033284 (1)