19 unknown, 18 not yet recruiting, 14 recruiting, 7 completed. 12 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Recruiting 4, Completed 3, Not yet recruiting 3, Unknown 2 |
| Phase 2 | 1 | Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Right Heart and Lung Blood Flow During Exercise (RIGHT-NET 2.0) Right Ventricular Dysfunction, Cardiopulmonary Diseases | Not yet recruiting | IRCCS SYNLAB SDN | 2000 | 2027-01-01 | 2026-10-01 | |
| Epigenetic Changes in Long COVID Patients Long COVID-19 Syndrome, Long COVID Symptoms | Not yet recruiting | Istituti Clinici Scientifici Maugeri SpA | 1000 | 2026-09-01 | 2026-08-11 | |
| Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables Active Aging Individuals Aged 65 and Over, Aging | Not yet recruiting | Neuromed IRCCS | 265 | 2026-09-01 | 2026-06-11 | |
| PANORAMA: Neuromuscular Organoids for Refractory AChR+ Myasthenia Gravis Myasthenia Gravis Generalized | Recruiting | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 40 | 2026-06-04 | 2026-07-21 | |
| A Study of Barrett's Esophagus Patients: Optimization of a Risk Model to Better Predict the Development of Cancer Recurrence and the Effect of Risk Profile Disclosure on Patient Quality of Life and Fear of Cancer Risk profile disclosure - Barrett Esophagus, Barrett Esophagus Adenocarcinoma | Not applicable | Not yet recruiting | University Hospital, Antwerp | 266 | 2026-06-01 | 2026-03-06 |
| Observational, Retrospective, Single-center Study Aimed at Evaluating Long-term Outcomes Following Transvenous Lead Extraction of Infected Cardiac Implantable Electronic Devices. Cardiac Implantable Electronic Device (CIED) | Not yet recruiting | IRCCS Ospedale San Raffaele | 300 | 2026-05-01 | 2026-04-15 | |
| Ultrasound Measurement of Thyroid Volume in Term Newborns Thyroid ultrasound - Thyroid Volume, Thyroid Ultrasound | Not yet recruiting | IRCCS Ospedale San Raffaele | 400 | 2026-05-01 | 2026-05-12 | |
| Quality of Life, Psychological Impact, and Care-related Challenges in Patients Affected by Von Hippel-Lindau Syndrome. VHL - Von Hippel-Lindau Syndrome | Active not recruiting | IRCCS Ospedale San Raffaele | 200 | 2026-05-01 | 2026-05-11 | |
| Comparative Outcomes of Radiofrequency Ablation of Concealed and Manifest Accessory Pathways: a Single Center, Retrospective Observational Study Atrioventricular Reentrant Tachycardias, Wolff-Parkinson-White (WPW) Syndrome | Not yet recruiting | IRCCS Ospedale San Raffaele | 220 | 2026-04-01 | 2026-02-27 | |
| APT-weighted and Diffusion MRI for Characterizing Tumor Infiltration in High-Grade Gliomas Standard-of-care MRI data, including APT and diffusion imaging, will be analyzed to generate quantitative maps of tumor infiltration within the peri-tumoral region. - High-Grade Glioma, Glioblastoma | Not yet recruiting | IRCCS Ospedale San Raffaele | 20 | 2026-04-01 | 2026-04-15 | |
| CAT-VHL Exploring the Role of Carbonic Anhydrase IX as Diagnostic and Theranostic Target in Von-Hippel Lindau Disease investigating the role of CAIX as target in VHL disease and in VHL-/- tumors. - VHL - Von Hippel-Lindau Syndrome | Phase 2 | Recruiting | IRCCS Ospedale San Raffaele | 38 | 2026-02-25 | 2026-03-09 |
| Autoimmune Hyperthyroidism in Prepubertal Children restrospective observational study - Autoimmune Hyperthyroidism, Children | Enrolling by invitation | IRCCS Ospedale San Raffaele | 100 | 2026-01-01 | 2026-04-22 | |
| Hepatitis B and C Within the Chinese Community in Milan HBV (Hepatitis B Virus), HCV Infection | Not yet recruiting | IRCCS Ospedale San Raffaele | 1000 | 2025-12-01 | 2025-11-21 | |
| Prospective Observational Analysis of Circulating Endocan Levels in Patients Presenting With Acute Diverticulitis Diverticulitis | Not yet recruiting | IRCCS Ospedale San Raffaele | 60 | 2025-09-30 | 2025-06-18 | |
| Metabolic Risk Assessment in Prepubertal Children With Congenital Hypothyroidism prospective observational study (clinical, hormonal and auxological data) - Congenital Hypothyroidism, Metabolic Syndrome | Not yet recruiting | Buzzi Children's Hospital | 170 | 2025-09-01 | 2025-08-17 | |
| A Study of Barrett's Esophagus Patients to Investigate Quality of Life and Fear of Cancer, and Optimize a Risk Model Based on Biomarkers and New Technologies to Better Predict the Development of Cancer Endoscopic brush cytology - Barrett's Esophagus, Esophageal Adenocarcinoma | Not applicable | Recruiting | University Hospital, Antwerp | 50 | 2025-08-13 | 2026-02-24 |
| Non-Invasive Programmed Stimulation (NIPS) to Guide the Subsequent VT Therapeutic Strategies Re-Do ventricular tachycardia ablation, Antiarrhythmic Drug Therapy (amiodarone, sotalol, or mexiletine) - Ventricular Tachycardia (VT) | Not applicable | Recruiting | IRCCS Ospedale San Raffaele | 51 | 2025-06-12 | 2026-03-27 |
| Impact of Exclusion Diet in Addition to Anti-TNF Therapy in Crohn's Disease and Ulcerative Colitis: a Prospective, Randomized, Double-arm, Open-label Study CDED (Crohn's Disease Exclusion Diet) in addition to anti-TNF therapy, Anti-TNF Therapy - Ulcerative Colitis (UC), Crohn Disease (CD) | Not applicable | Recruiting | IRCCS Ospedale San Raffaele | 80 | 2025-05-22 | 2026-01-22 |
| The Italian Alliance for Cardiovascular Rehabilitation and Prevention (ITACARE-P) Registry: An Observational Study on Cardiac Rehabilitation in Patients With Coronary Disease or Heart Failure Cardiac Rehab, Heart Failure | Recruiting | Fondazione Don Carlo Gnocchi ETS | 1600 | 2025-05-01 | 2026-09-29 | |
| Defining the Role of Optical Super-high Magnification Dermoscopy in the Diagnosis of Skin Tumors Skin Cancers | Not yet recruiting | IRCCS Ospedale San Raffaele | 1000 | 2025-04-01 | 2025-04-03 |
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Heart Failure (3) · Heart Valve Diseases (3) · Adenomatous Polyposis Coli (2) · Barrett Esophagus (2) · Colitis, Ulcerative (2) · Congenital Hypothyroidism (2) · Crohn Disease (2) · Prostatic Neoplasms (2) · Stroke (2) · Tachycardia, Ventricular (2) · Tricuspid Valve Insufficiency (2) · von Hippel-Lindau Disease (2) · Acanthamoeba Keratitis (1) · Adenocarcinoma (1) · Adenocarcinoma Of Esophagus (1)
Abiraterone Acetate (1) · Amiodarone (1) · Cardiopulmonary Resuscitation (1) · Diffusion Magnetic Resonance Imaging (1) · Docetaxel (1) · Genetic Linkage (1) · Immunonutrition Diet (1) · Lead (1) · Mandibular Advancement (1) · Mexiletine (1) · Septal Occluder Device (1) · Sotalol (1) · Wearable Electronic Devices (1) · apalutamide (1) · darolutamide (1)
Italy (45) · Belgium (2) · Denmark (2) · France (2) · Ireland (2) · Sweden (2) · Germany (1) · Switzerland (1) · Turkey (Türkiye) (1)
Tommaso Lo Parigi, MD (2) · Alberto Zangrillo, MD (1) · Alessandra Decataldo, PhD (1) · Antonella Castagna, Prof (1) · Claudio Fiorino, Msc (1) · Francesca Guzzo, MD (1) · Francesco Maisano, Head of Cardiac Surgery (1) · Giorgio Gastaldi, MD, DDS (1) · Luana Dr Gilio (1) · Marco Metra, MD (1) · Marco Salvatore, MD,PhD (1) · Marco Vitellaro, M.D. (1) · Marco Vitellaro, MD (1) · Maria E Street, MD, PhD (1) · Michele Tinazzi, PhD (1)
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