5 completed, 2 not yet recruiting, 1 unknown. 4 Phase 3, 1 Not applicable, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4 | Completed 4 |
| Not applicable | 1 | Unknown 1 |
| Phase 2 | 1 | Not yet recruiting 1 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow Natamycin: new trials by email Literature Review of Natamycin trials Research Report on Natamycin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Lid Eradication of Antifungal-Responsive FUNGUS Study NATACYN® - Anterior Blepharitis | Phase 4 | Not yet recruiting | Brent Kramer | 60 | 2026-10-01 | 2026-10-02 |
| Trial to Evaluate the Efficacy And Safety of IVIEW-1201 In the Treatment of Fungal Keratitis IVIEW-1201, NATACYN® - Fungal Keratitis | Phase 2 | Not yet recruiting | IVIEW Therapeutics Inc. | 60 | 2026-08-01 | 2025-10-15 |
| Efficacy and Safety of Natamycin and Lactulose Vaginal Suppositories in Treatment of Vulvovaginal Candidiasis Natamycin + Lactulose 100 mg + 300 mg vaginal suppositories, Lactulose 300 mg vaginal suppositories, Pimafucin® (natamycin) 100 mg vaginal suppositories - Vulvovaginal Candidiasis, Genital | Phase 3 | Completed | Avva Rus, JSC | 218 | 2022-12-29 | 2024-05-13 |
| Rose Bengal Electromagnetic Activation With Green Light for Infection Reduction Moxifloxacin Ophthalmic, Chlorhexidine Gluconate, Natamycin - Acanthamoeba Keratitis, Fungal Keratitis | Phase 3 | Completed | University of California, San Francisco | 330 | 2022-08-03 | 2026-09-03 |
| The Antibiogram and Outcomes of Antimicrobial Regimens in Microbial Keratitis: A Prospective Cohort Study Moxifloxacin Ophthalmic 0.5% Ophthalmic Solution, Ceftazidime 5% + vancomycin 5%, Gentamicin 1.4% + vancomycin 5% - Bacterial Keratitis, Fungal Keratitis | Completed | Alexandria University | 123 | 2021-12-31 | 2024-01-25 | |
| Mycotic Antimicrobial Localized Injection for Treatment of Corneal Ulcers Intrastromal voriconazole, Natamycin - Corneal Ulcer, Fungal Keratitis | Phase 3 | Completed | University of California, San Francisco | 70 | 2016-09-01 | 2025-09-25 |
| Clinical & Visual Outcomes of Collagen Cross Linking for Fungal Keratitis collagen crosslinking group, Topical anti-fungal therapy - Mycotic Corneal Ulcer | Not applicable | Unknown | Aravind Eye Care System | 20 | 2014-02-01 | 2014-12-31 |
| Mycotic Ulcer Treatment Trial I Natamycin, Voriconazole - Corneal Ulcer, Eye Infections, Fungal | Phase 3 | Completed | University of California, San Francisco | 323 | 2010-04-01 | 2018-08-01 |
Corneal Ulcer (2) · Acanthamoeba Keratitis (1) · Candidiasis, Vulvovaginal (1) · Corneal Diseases (1) · Eye Diseases (1) · Eye Infections, Fungal (1) · Hypersensitivity (1) · Keratitis (1) · Mycoses (1) · Pruritus (1) · Ulcer (1)
University of California, San Francisco (3) · Alexandria University (1) · Aravind Eye Care System (1) · Avva Rus, JSC (1) · Brent Kramer (1) · IVIEW Therapeutics Inc. (1)
India (4) · United States (3) · Brazil (1) · Egypt (1) · Russia (1)
Jennifer Rose-Nussbaumer, MD (2) · Tom Lietman, MD (2) · Amira A Nayel, PharmD (1) · Dr. Venkatesh Prajna, DNB,FRCS (1) · NV Prajna, DNB, FRC Ophth (1) · Nelly M Mohamed, PhD (1) · Nicole Varnado, MPH (1) · Nisha Acharya, MD, MS (1) · Noha A Hamdy, PhD (1) · Tamer H Massoud, PhD (1)
PMID 23702779, PMID 25764482, PMID 25841317, PMID 26531051, PMID 27054515, PMID 27787540, PMID 28426856, PMID 28817744, PMID 32557558, PMID 35024776, PMID 39011096, PMID 39192339, PMID 39979898, PMID 41561665, PMID 42348235
U10EY018573 (1), UG1EY028518 (1)