56 completed, 18 unknown, 11 terminated, 7 not yet recruiting. 56 Phase 2, 45 Phase 3, 10 Phase 1, 8 Not applicable, 8 Phase 4.
Follow nitazoxanide: new trials by email Literature Review of nitazoxanide trials Research Report on nitazoxanide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nitazoxanide as Adjunct Therapy in Mild-to-Moderate Ulcerative Colitis Nitazoxanide (NTZ) - Ulcerative Colitis (UC) | Phase 2 / Phase 3 | Not yet recruiting | Tanta University | 44 | 2027-01-01 | 2026-09-15 |
| Nitazoxanide for Treatment of Cryptosporidium in Children Nitazoxanide, Placebo - Cryptosporidiosis | Phase 3 | Not yet recruiting | Johns Hopkins Bloomberg School of Public Health | 480 | 2026-12-30 | 2026-09-28 |
| Phase 2 Study of 500 mg BID NTZ on Top of Standard of Care in Patients With Acute Decompensation of Liver Cirrhosis at High Risk of Progression to Acute-on-Chronic Liver Failure or Established Acute-on-Chronic Liver Failure NTZ 500mg BID on top of SOC - Acute Decompensation of Liver Cirrhosis, Established Acute-on-Chronic Liver Failure | Phase 2 | Not yet recruiting | Genfit | 16 | 2026-10-01 | 2026-07-09 |
| Nitazoxanide in Spontaneous Bacterial Peritonitis Nitazoxanide (NTZ), Placebo - SBP - Spontaneous Bacterial Peritonitis | Phase 1 / Phase 2 | Not yet recruiting | Tanta University | 60 | 2026-09-01 | 2026-09-08 |
| A Clinical Trial Evaluating Fecal Microbiota Transplantation (FMT) in Adolescents With ADHD Fecal Microbiota Transplant (FMT), Nitazoxanide 500mg BID, Vancomycin 250mg BID - ADHD, ADHD - Attention Deficit Disorder With Hyperactivity | Phase 2 | Not yet recruiting | University of Calgary | 64 | 2026-08-31 | 2026-09-10 |
| Nitazoxanide in Patients With Ulcerative Colitis Mesalamine, Nitazoxanide - Ulcerative Colitis | Phase 2 | Recruiting | Alexandria University | 70 | 2025-05-30 | 2025-06-27 |
| Efficacy and Safety of Nitazoxanide 600 Mg in the Outpatient Treatment of COVID-19 and Influenza Nitazoxanide 600Mg Oral Tablet / placebo oral tablet - Covid 19, Influenza | Phase 3 | Not yet recruiting | Azidus Brasil | 340 | 2025-02-01 | 2025-02-10 |
| Efficacy of Nitazoxanide Based Therapy vs Standard Triple Therapy in H-pylori in Children Nitazoxanide, Metronidazole, PPI - Helicobacter Pylori Infection | Not applicable | Completed | Muhammad Aamir Latif | 66 | 2025-01-01 | 2025-07-25 |
| Trial to Evaluate Nitazoxanide for Treatment of Mild COVID-19 in Subjects Not at High Risk of Severe Illness Nitazoxanide, Placebo, Vitamin Super-B Complex - COVID-19 | Phase 3 | Withdrawn | Romark Laboratories L.C. | 2024-08-01 | 2024-09-24 | |
| Trial to Evaluate Nitazoxanide for Treatment of Mild or Moderate COVID-19 in Subjects at High Risk of Severe Illness Nitazoxanide, Vitamin Super-B Complex, Placebo - COVID-19 | Phase 3 | Withdrawn | Romark Laboratories L.C. | 2024-08-01 | 2024-09-24 | |
| Nitazoxanide vs Metronidazole for Entamoeba Diarrhea in Children Nitazoxanide, Metronidazole - Entamoeba Histolytica Diarrhea | Phase 2 | Completed | University of Child Health Sciences and Children's Hospital, Lahore | 90 | 2024-04-02 | 2026-08-27 |
| Nitazoxanide as Adjuvant Therapy in Type 2 Diabetes Mellitus Nitazoxanide - Diabetes Mellitus, Type 2 | Phase 2 | Unknown | Tanta University | 70 | 2023-10-01 | 2023-08-25 |
| Combination Therapy Between Doxycycline, Pentoxifylline, and Nitazoxanide in Sexually Active Men Doxycyclin, Pentoxifylline, Nitazoxanide 500Mg Oral Tablet - Sexually Transmitted Diseases | Phase 2 / Phase 3 | Not yet recruiting | Tanta University | 100 | 2023-06-20 | 2023-06-12 |
| Nitazoxanide in Patients With Metastatic Colorectal Cancer Nitazoxanide - Metastatic Colorectal Cancer | Phase 3 | Unknown | Tanta University | 60 | 2023-03-01 | 2023-09-22 |
| Effect of the Nutritional Support System on Neuromotor Alterations in Patients With Cerebral Palsy Probiotics, NSS Nutritional Support System, Deworming - Cerebral Palsy, Spastic | Not applicable | Unknown | Anahuac University | 144 | 2023-01-16 | 2023-02-01 |
| Role of Nitazoxanide and Escitalopram in Patients With Rheumatoid Arthritis Placebo, Nitazoxanide 500Mg Oral Tablet, Escitalopram 10mg - Rheumatoid Arthritis | Phase 3 | Completed | Tanta University | 90 | 2022-12-02 | 2023-04-25 |
| Comparing the Efficacy of Nitazoxanide Versus Rifaximin in Adult Patients With Irritable Bowel Syndrome Without Constipation Nitazoxanide 500Mg Oral Tablet, Rifaximin 550Mg Tab - Irritable Bowel Syndrome With Diarrhea | Phase 1 / Phase 2 | Withdrawn | Sadat City University | 2022-07-01 | 2025-07-14 | |
| Efficacy and Safety of Nitazoxanide 600 mg BID Versus Placebo for the Treatment of Hospitalized Patients With COVID-19 Nitazoxanide, Placebo - covid19 | Phase 3 | Unknown | Azidus Brasil | 380 | 2022-06-22 | 2022-10-31 |
| Nitazoxanide Pharmacokinetic Parameters in Renal Impaired Subjects Nitazoxanide - Renal Impairment, Renal Disease | Phase 1 | Completed | Genfit | 77 | 2022-04-25 | 2022-10-28 |
| Potassium Copetitive Acid Blockers Efficacy in H.Pylori Eradication Vonoprazan - Helicobacter Pylori Eradication | Phase 3 | Completed | Ain Shams University | 232 | 2022-01-01 | 2023-10-26 |
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COVID-19 (26) · Hepatitis C, Chronic (10) · HIV Infections (8) · Coronavirus Infections (7) · Cryptosporidiosis (6) · Influenza, Human (6) · Hepatitis C (4) · AIDS-Related Opportunistic Infections (3) · Colitis, Ulcerative (3) · Diarrhea (3) · Hepatic Encephalopathy (3) · Rotavirus Infections (3) · Severe Acute Respiratory Syndrome (3) · Amebiasis (2) · Diabetes Mellitus, Type 2 (2)
Romark Laboratories L.C. (29) · Tanta University (14) · Azidus Brasil (5) · National Institute of Allergy and Infectious Diseases (NIAID) (5) · Genfit (3) · Ain Shams University (2) · Obafemi Awolowo University (2) · Sherief Abd-Elsalam (2) · Telethon Kids Institute (2) · Universidade Federal do Rio de Janeiro (2) · ANRS, Emerging Infectious Diseases (1) · Alexandria University (1) · American Academy of Family Physicians (1) · Anahuac University (1) · Assiut University (1)
United States (29) · Egypt (25) · Brazil (6) · Mexico (6) · Australia (5) · South Africa (5) · Pakistan (4) · Puerto Rico (4) · Argentina (2) · Canada (2) · Nigeria (2) · Thailand (2) · Bangladesh (1) · Belgium (1) · Bolivia (1)
Yehia El-Gohary, MD (5) · Asem Elfert, MD (4) · Jean-Francois Rossignol, M.D., Ph.D. (4) · Samir M Kabil, MD (3) · Arthur Berman, DO (2) · Carol Addy, MD (2) · David Johnson, MD (2) · Ira Jacobson, MD (2) · Mona Abu-Zekry, MD (2) · Norman Gitlin, MD (2) · Patricia RM Rocco, MD, PhD (2) · Sherief Abd-Elsalam, lecturer (2) · Stephen Harrison, MD (2) · Abeer Salamah, Lecturer (1)
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