152 completed, 30 unknown, 14 withdrawn, 8 recruiting. 54 Not applicable, 46 Phase 3, 45 Phase 2, 21 Phase 4, 17 Phase 1.
Follow Keratitis: new trials by email Literature Review of Keratitis trials Research Report on Keratitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fluorometholone Study Adjunctive Topical Fluorometholone (FML) 0.1%, Standard Topical Antibiotic Therapy - Keratitis Bacterial, Corneal Ulcer (Diagnosis) | Phase 2 | Not yet recruiting | Vishal Jhanji | 174 | 2026-10-31 | 2026-06-10 |
| Clinical Predictors of Visual Outcome in Patients Affected With Ocular Surface Diseases Neurotrophic Keratopathy, Exposure Keratopathy | Not yet recruiting | IRCCS San Raffaele | 1000 | 2026-07-01 | 2026-07-14 | |
| Follow-up Compliance for Corneal Ulcer Patients With SMS Reminder SMS reminder - Corneal Ulcer | Not applicable | Recruiting | Seva Canada Society | 310 | 2026-02-23 | 2026-05-12 |
| Open-label Prospective Clinical Trial Evaluating the Safety and Efficacy of Biosynthetic CLP-PEG-MPC Corneal Implants in Patients Undergoing High-risk Deep Anterior Lamellar Keratoplasty. CLP-PEG-MPC, Human donor cornea penetrating keratoplasty - High-risk Corneal Transplantation, Corneal Blindess | Not applicable | Withdrawn | Centre hospitalier de l'Université de Montréal (CHUM) | 2026-01-01 | 2022-12-28 | |
| Pattern of Microbial Keratitis in Assiut University Hospital corneal scraping including direct smear, culture and sensitivity - Keratitis, Microbial Keratitis | Not yet recruiting | Assiut University | 100 | 2026-01-01 | 2026-01-05 | |
| A Dose Regimen Study of BRM421 Ophthalmic Solution in Patients With Dry Eye Disease BRM421 Ophthalmic Solution, 0.03%, Artificial Tear, BRM421 Ophthalmic Solution, 0.06% - Dry Eye Disease (DED), Keratoconjunctivitis Sicca | Phase 2 | Not yet recruiting | BRIM Biotechnology Inc. | 99 | 2025-12-01 | 2025-10-20 |
| Retrospective Chart Review of Patients With Acanthamoeba Keratitis Who Have Received 0.8 mg/mL Polihexanide as Part of the "Medicines in Special Situations" (Medicamentos en Situaciones Especiales) Program in Spain. PHMB 0.08% - Acanthamoeba Keratitis | Completed | SIFI SpA | 23 | 2025-10-30 | 2026-06-22 | |
| Clinical Study of Intrastromal Anti-VEGF Injection for Corneal Neovascularization. Intrastromal anti-VEGF injection and topical antiviral eye drops, Conventional antiviral topical ocular drops. - Herpes Simplex Keratitis, Corneal Neovascularization | Phase 1 / Phase 2 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 100 | 2025-10-01 | 2026-01-09 |
| Intrastromal Moxifloxacin as an Adjunctive Therapy in Recalcitrant Bacterial Keratitis Intrastromal moxifloxacin injection plus standard topical moxifloxacin therapy, Standard topical moxifloxacin therapy alone - Bacterial Keratitis, Recalcitrant Infectious Keratitis | Not applicable | Recruiting | Minia University | 60 | 2025-10-01 | 2026-09-10 |
| Fungal Ulcer Treatment Augmented With Natamycin and Cyclosporine A Cyclosporine A, Placebo Comparator: Placebo - Fungal Keratitis, Corneal Ulcer | Phase 3 | Recruiting | University of California, San Francisco | 150 | 2025-09-01 | 2026-06-05 |
| Tolerability and Efficacy Study of Reinnerva/Lubristil+G vs Vismed Reinnerva/Lubristil +G sterile eye drops (artificial tears), Vismed sterile eye drops (artificial tears) - Keratoconjunctivitis Sicca | Not applicable | Completed | Medivis SRL | 40 | 2025-06-09 | 2026-02-19 |
| Corneal Topography in Vernal Keratoconjunctivitis pentacam - Keratoconjunctivitis | Not yet recruiting | Assiut University | 44 | 2025-06-01 | 2024-12-24 | |
| Diagnosing Corneal Infection Corneal impression membrane (Millicell Cell Culture Insert, 12mm, hydrophilic PTFE 0.4µm (PICM01250)) - Corneal Ulcer (Diagnosis) | Withdrawn | University of Edinburgh | 2025-02-01 | 2026-02-27 | ||
| Topical Ganciclovir Versus Systemic Aciclovir in the Treatment of Herpetic Keratitis Acyclovir 400 MG, Ganciclovir (GCV) - Herpetic Keratitis | Not applicable | Completed | Al-Azhar University | 20 | 2024-10-01 | 2025-01-03 |
| Retrospective Chart Review of Patients With Acanthamoeba Keratitis Who Have Received 0.8 mg/ml Polihexanide Acanthamoeba Keratitis | Completed | SIFI SpA | 40 | 2024-09-30 | 2025-10-01 | |
| Parasitic Ulcer Treatment Trial Polyhexamethylene biguanide (PHMB), Topical corticosteroid, Topical placebo - Acanthamoeba Keratitis | Phase 3 | Recruiting | Jeremy Keenan, MD, MPH | 232 | 2024-07-01 | 2026-10-01 |
| Acanthamoeba and Artificial Intelligence Acanthamoeba Keratitis, Artificial Intelligence | Unknown | IRCCS Ospedale San Raffaele | 151 | 2024-05-01 | 2024-05-10 | |
| Open-label Trial to Evaluate Efficacy and Safety of rhNGF on Corneal Thickness Via AS-OCT in Neurotrophic Keratitis OXERVATE® 0.002% - Neurotrophic Keratitis, Neurotrophic Keratopathy | Phase 4 | Withdrawn | Dompé Farmaceutici S.p.A | 2024-04-26 | 2024-12-02 | |
| Study of INV-102 Ophthalmic Solution in Adults With Moderate to Severe Dry Eye Disease INV-102, Vehicle - Dry Eye Disease | Phase 2 | Completed | Invirsa, Inc. | 109 | 2024-03-27 | 2026-09-18 |
| Vizol S DIGI EYE Efficacy and Safety Study in Patients With Dry Eye Vizol S DIGI EYE eye drops, 0,9% saline solution, eye drops - Dry Eye Disease (DED) | Phase 3 | Completed | Jadran Galenski laboratorij d.d. | 86 | 2024-03-20 | 2025-07-03 |
Showing 20 of 218. Sign in to see all of them.
Keratoconjunctivitis Sicca (85) · Dry Eye Syndromes (75) · Corneal Ulcer (55) · Corneal Diseases (19) · Keratoconjunctivitis (17) · Conjunctivitis (14) · Keratitis, Herpetic (13) · Acanthamoeba Keratitis (10) · Sjogren's Syndrome (10) · Eye Diseases (9) · Cataract (6) · Pterygium (6) · Blepharitis (5) · Corneal Dystrophies, Hereditary (5)
Eye Diseases (209) · Corneal Diseases (199) · Conjunctival Diseases (115) · Conjunctivitis (97) · Lacrimal Apparatus Diseases (93) · Infections (90) · Keratoconjunctivitis (84) · Eye Infections (83) · Pathological Conditions, Signs and Symptoms (24) · Dry Eye Syndromes (19) · Virus Diseases (19) · DNA Virus Infections (18) · Herpesviridae Infections (16) · Skin and Connective Tissue Diseases (16)
Lubricant Eye Drops (9) · Cyclosporine (6) · Loteprednol Etabonate (6) · Ophthalmic Solutions (6) · Cyclosporins (5) · Acyclovir (4) · Adrenal Cortex Hormones (4) · Fluorometholone (4) · Moxifloxacin (4) · Riboflavin (4) · rebamipide (4) · Corneal Cross-Linking (3) · Dexamethasone (3) · Ganciclovir (3) · Hyaluronic Acid (3)
University of California, San Francisco (9) · National Eye Institute (NEI) (7) · Allergan (5) · National Taiwan University Hospital (4) · Oculeve, Inc. (4) · SIFI SpA (4) · Sun Pharmaceutical Industries Limited (4) · Assiut University (3) · Centre hospitalier de l'Université de Montréal (CHUM) (3) · Federal University of São Paulo (3) · Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA (3) · Kala Pharmaceuticals, Inc. (3) · Mimetogen Pharmaceuticals USA, Inc. (3) · Minia University (3) · Mitotech, SA (3)
United States (94) · France (14) · China (13) · India (12) · Egypt (10) · Taiwan (9) · Brazil (8) · Spain (8) · United Kingdom (8) · Austria (5) · Italy (5) · Germany (4) · Nepal (4) · Denmark (3) · Israel (3)
Gail Torkildsen, MD (4) · Tom Lietman, MD (3) · Bala Ambati (2) · Garth Cumberlidge, PhD (2) · Gary Foulks, MD (2) · Jennifer Rose-Nussbaumer, MD (2) · Jodi Luchs, MD (2) · Lawrence T Friedhoff, MD, PhD (2) · Michelle Senchyna (2) · NV Prajna, DNB, FRC Ophth (2) · Nisha Acharya, MD, MS (2) · Robert Shalwitz, MD (2) · Yvette Viscuso (2)
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U10EY018573 (2), R01EY031033 (1), R34EY017626 (1), U10EY015114 (1), U10EY022880 (1), UG1EY028518 (1), UG1EY033284 (1)