8 completed, 4 not yet recruiting, 3 recruiting, 2 enrolling by invitation. 12 Not applicable, 5 Phase 2, 2 Phase 1, 1 Phase 3.
Follow Alcohol Abstinence: new trials by email Literature Review of Alcohol Abstinence trials Research Report on Alcohol Abstinence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and Craving Cannabidiol (CBD), Placebo - Alcohol Use Disorder (AUD), Withdrawal From Addictive Substance; Detoxification | Phase 2 / Phase 3 | Recruiting | Johns Hopkins University | 105 | 2026-11-01 | 2026-10-02 |
| Intravenous Acetate as an Adjunctive Treatment for Alcohol Withdrawal in Hospitalized Patients Sodium Acetate, Placebo - Alcohol Withdrawal, Alcohol Abstinence | Phase 1 / Phase 2 | Not yet recruiting | University of Colorado, Denver | 75 | 2026-09-01 | 2026-09-09 |
| Financial Rewards for Reducing Alcohol Use in Patients With Liver Disease PEth Based Contingency Management, PEth Monitoring with Fixed Incentives - Alcohol Use Disorder, Alcohol-associated Liver Disease | Not applicable | Not yet recruiting | Massachusetts General Hospital | 90 | 2026-08-01 | 2026-03-12 |
| The Use of Telephone-based ACT for Quitting Alcohol in the Young Population With Hazardous or Harmful Alcohol Use. Telephone-based ACT, Telephone-based social support - Alcohol Abstinence | Not applicable | Not yet recruiting | The Hong Kong Polytechnic University | 288 | 2026-08-01 | 2026-03-04 |
| SER-ABS-AUD: Neuropsychosocial-Spiritual Correlates of Serene Abstinence in Adults With AUD Alcohol Use Disorder (AUD), Alcohol Abstinence | Enrolling by invitation | Grigore T. Popa University of Medicine and Pharmacy | 70 | 2026-04-20 | 2026-10-06 | |
| Alcohol as a Modifiable Risk Factor for Atrial Fibrillation alcohol abstinence - Atrial Fibrillation (AF) | Not applicable | Not yet recruiting | Copenhagen University Hospital, Rigshospitalet | 414 | 2026-04-20 | 2026-04-14 |
| Endourage Complete Spectrum Oral Mucosal Drops (OMD) in Adults Desiring a Reduction in Ethanol Use Endourage 1200 mg OMD ™ Oral Mucosal Drops, Isolate, Placebo - Alcohol Drinking, Alcohol Use, Unspecified | Not applicable | Withdrawn | Endourage, LLC | 2025-09-01 | 2025-08-07 | |
| Virtual Incentive Treatment for Alcohol Contingency Management, Computer Based Training for Cognitive Behavioral Therapy for AUD (CBT4CBT) - Alcohol Use Disorder, Alcohol Drinking | Not applicable | Recruiting | Washington State University | 200 | 2024-06-18 | 2025-05-30 |
| Feasibility of Telephone-based Acceptance and Commitment Therapy in Hong Kong Chinese Young Adults With Alcohol Use Disorder: A Pilot Study ACT, Social support - Alcohol Use Disorder, Alcohol Abstinence | Not applicable | Active not recruiting | The Hong Kong Polytechnic University | 60 | 2023-04-01 | 2026-03-30 |
| Safety & Efficacy of Baclofen for Alcohol Withdrawal in Chronic Liver Disease With Active Alcohol Consumption Baclofen - Alcoholic Cirrhosis, Alcohol Abstinence | Enrolling by invitation | Corporacion Parc Tauli | 120 | 2022-12-22 | 2025-02-21 | |
| Reducing Blood Pressure in Mid-life Adult Binge Drinkers Exercise Training, Alcohol Abstinence Intervention - Alcohol Drinking, Binge Drinking | Not applicable | Recruiting | The University of Texas at Arlington | 55 | 2022-11-21 | 2026-06-01 |
| Evaluation of Sodium Excretion and Dietary Intake Via a New Sodium Food Frequency Questionnaire Dietary Assessment (BTS-Salt), Urinary Analysis (Gold Standard vs. Practical), Nutritional Monitoring - Healthy Adult, Alcohol Abstinence | Not applicable | Completed | Toros University | 100 | 2022-01-01 | 2026-07-22 |
| Alkontrol-herbal Effects on Alcohol Drinking kudzu extract, puerarin, Placebo control - Alcohol Drinking, Alcohol Use Disorder | Phase 2 | Completed | Mclean Hospital | 28 | 2018-01-01 | 2020-07-29 |
| Guanfacine to Reduce Relapse Risk in Women With Alcohol Use Disorder (AUD) Guanfacine XR 3mgs/daily, Placebo (for guanfacine) - Alcohol Abstinence | Phase 1 / Phase 2 | Completed | Stony Brook University | 32 | 2017-07-12 | 2024-06-05 |
| Interest of tDCS in Help for Supporting Alcohol Abstinence Active tDCS stimulations, Sham tDCS - Alcoholic Intoxication | Not applicable | Completed | Centre Hospitalier Henri Laborit | 90 | 2017-02-08 | 2026-01-13 |
| A Web Application to Reduce Heavy Drinking in First-time DWI Offenders Right Turns web application, Treatment as usual - Driving While Intoxicated, Driving Under the Influence | Not applicable | Completed | Behavior Therapy Associates, LLP | 58 | 2014-05-01 | 2017-02-01 |
| Family Based Prevention of Alcohol and Risky Sex for Older Teens Smart Choices 4 Teens - Alcohol Drinking, Alcohol Intoxication | Not applicable | Completed | Pacific Institute for Research and Evaluation | 411 | 2013-04-01 | 2023-07-27 |
| Intervention to Motivate Teens to be a Designated Organ Donor on Driver's License Organ Donor, Alcohol Prevention - Tissue and Organ Procurement, Alcohol Abstinence | Not applicable | Completed | University of Hawaii | 429 | 2008-04-01 | 2015-06-25 |
| Maximizing the Efficacy of Cognitive Behavior Therapy and Contingency Management Standard CBT, CBT+CM/adherence, CM/abstinence - Marijuana Dependence | Phase 2 | Completed | Yale University | 205 | 2004-12-01 | 2011-09-27 |
Alcoholism (9) · Alcohol Drinking (6) · Alcohol-Related Disorders (2) · Alcoholic Intoxication (2) · Liver Cirrhosis, Alcoholic (2) · Aneurysm (1) · Anhedonia (1) · Atrial Fibrillation (1) · Behavior (1) · Binge Drinking (1) · Coitus (1) · Driving Under the Influence (1) · Drug-Related Side Effects and Adverse Reactions (1) · Liver Diseases (1)
Drinking Behavior (19) · Behavior (18) · Chemically-Induced Disorders (14) · Substance-Related Disorders (14) · Mental Disorders (13) · Alcohol-Related Disorders (11) · Pathological Conditions, Signs and Symptoms (5) · Pathologic Processes (4) · Alcohol-Induced Disorders (2) · Cardiovascular Diseases (2) · Digestive System Diseases (2) · Fibrosis (2) · Health Behavior (2) · Liver Cirrhosis (2) · Liver Diseases, Alcoholic (2)
Ethanol (4) · Baclofen (1) · Cannabidiol (1) · Cognitive Behavioral Therapy (1) · Exercise (1) · Guanfacine (1) · Nutrition Assessment (1) · Saline Solution (1) · Sodium Acetate (1) · Sugars (1) · Therapeutics (1) · peppermint oil (1) · puerarin (1)
The Hong Kong Polytechnic University (2) · Behavior Therapy Associates, LLP (1) · Centre Hospitalier Henri Laborit (1) · Copenhagen University Hospital, Rigshospitalet (1) · Corporacion Parc Tauli (1) · Endourage, LLC (1) · Grigore T. Popa University of Medicine and Pharmacy (1) · Johns Hopkins University (1) · Massachusetts General Hospital (1) · Mclean Hospital (1) · Pacific Institute for Research and Evaluation (1) · Stony Brook University (1) · The University of Texas at Arlington (1) · Toros University (1) · University of Colorado, Denver (1)
United States (11) · France (1) · Hong Kong (1) · Romania (1) · Spain (1) · Turkey (Türkiye) (1)
Alexandra M Gaina, MD (1) · Andreea S Szalontay, Clinical Professor (1) · Brenda A Miller, Ph.D. (1) · Cheryl Albright, PhD, MPH (1) · Chueh-Lung Hwang, PhD (1) · David Woliinsky, MD (1) · Ellen Burnham, MD (1) · Helen C Fox, PhD (1) · Kathleen Carroll, PhD (1) · Michael McDonell, PhD (1) · Nathalie Hill-Kapturczak, PhD (1) · Nematollah Jaafari, Professor (1) · Reid K Hester, Ph.D. (1) · Sean Murphy, PhD (1)
PMID 12648025, PMID 16251991, PMID 16699809, PMID 18422832, PMID 19560604, PMID 26373473, PMID 29172702, PMID 29307505, PMID 30146330, PMID 30640504, PMID 34128818, PMID 36001426, PMID 39824379
R00AA028537 (1), R01AA031013 (1), R01DK079684 (1), R34AA032300 (1)