2 completed, 1 active not recruiting, 1 not yet recruiting, 1 no longer available. 3 Phase 1, 2 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 1, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 2 | Completed 1, Not yet recruiting 1 |
| Phase 3 | 2 | Active not recruiting 1, Unknown 1 |
Follow Sodium Acetate: new trials by email Literature Review of Sodium Acetate trials Research Report on Sodium Acetate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intravenous Acetate as an Adjunctive Treatment for Alcohol Withdrawal in Hospitalized Patients Sodium Acetate, Placebo - Alcohol Withdrawal, Alcohol Abstinence | Phase 1 / Phase 2 | Not yet recruiting | University of Colorado, Denver | 75 | 2026-11-01 | 2026-10-30 |
| Prevention of Metabolic Acidosis in Preterm Neonates by Replacing Sodium Chloride With Sodium Acetate in Parenteral Nutrition sodium acetate group will receive sodium acetate in the neonatal PN., sodium chloride group will receive sodium chloride in the neonatal PN. - Metabolic Acidosis, Neonatal Disease | Phase 3 | Unknown | Aga Khan University Hospital, Pakistan | 200 | 2024-07-10 | 2024-08-09 |
| Human Models of Selective Insulin Resistance: Alpelisib, Part I Alpelisib 300 mg, Placebo, [1-13C] sodium acetate - Insulin Resistance, Prediabetic State | Phase 1 | Recruiting | Columbia University | 32 | 2024-04-24 | 2026-08-24 |
| Clinical Study of DTX301 AAV-Mediated Gene Transfer for Ornithine Transcarbamylase (OTC) Deficiency DTX301, Placebo, Oral Corticosteroids - OTC Deficiency | Phase 3 | Active not recruiting | Ultragenyx Pharmaceutical Inc | 37 | 2022-10-18 | 2026-09-09 |
| A Low ChloridE hyperTonic Solution for Brain Edema Sodium chloride /sodium acetate (16.4%), Sodium chloride (23.4%), PlasmaLyte - Subarachnoid Hemorrhage, Acute Kidney Injury | Phase 1 | Completed | Emory University | 59 | 2017-06-28 | 2023-05-01 |
| Fluid Therapy During Brain Tumor Resection in Children balanced crystalloid solution (components: sodium chloride, sodium gluconate, sodium acetate, potassium chloride and magnesium chloride), 0.9% sodium chloride - Brain Neoplasms | Phase 2 | Completed | Federal University of São Paulo | 53 | 2015-08-01 | 2017-11-14 |
| Clinical Management Decisions for Recurrent Prostate Cancer Patients Based on [11C]Acetate PET Scan [11C]Acetate - Prostate Cancer | No longer available | Wendell Yap, MD | 2018-05-16 |
Acid-Base Imbalance (1) · Acidosis (1) · Acute Kidney Injury (1) · Alcohol Abstinence (1) · Alcoholism (1) · Brain Neoplasms (1) · Fatty Liver (1) · Hyperinsulinism (1) · Hyperphagia (1) · Infant, Newborn, Diseases (1) · Insulin Resistance (1) · Non-alcoholic Fatty Liver Disease (1) · Obesity (1) · Ornithine Carbamoyltransferase Deficiency Disease (1) · Overweight (1)
Aga Khan University Hospital, Pakistan (1) · Columbia University (1) · Emory University (1) · Federal University of São Paulo (1) · Ultragenyx Pharmaceutical Inc (1) · University of Colorado, Denver (1) · Wendell Yap, MD (1)
United States (5) · Brazil (2) · Argentina (1) · Canada (1) · France (1) · Germany (1) · Japan (1) · Netherlands (1) · Pakistan (1) · Portugal (1) · Spain (1)
Ellen Burnham, MD (1) · Joshua R Cook, MD, PhD (1) · Owen Samuels, MD (1) · Wendell Yap, MD (1)
PMID 30428930, PMID 32391156, PMID 38171926
K12DK133995 (1), K23DK140614 (1)