92 completed, 39 unknown, 35 recruiting, 17 terminated. 54 Not applicable, 40 Phase 2, 26 Phase 3, 11 Phase 4, 8 Phase 1.
Follow Liver Diseases, Alcoholic: new trials by email Literature Review of Liver Diseases, Alcoholic trials Research Report on Liver Diseases, Alcoholic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pomegranate Dietary Supplements in AUD and ALD Pomegranate Dietary Ssupplement - Alcohol Use Disorder, Alcohol-associated Liver Disease | Not yet recruiting | University of Louisville | 144 | 2027-01-01 | 2026-07-24 | |
| Inflammatory and Neuroimmune Guided Investigation of Underlying Fatigue in Patients With Cirrhosis Cirrhosis Alcoholic, Fatigue Symptom | Not yet recruiting | King's College London | 50 | 2027-01-01 | 2026-10-27 | |
| Elastography-based Brief Alcohol Intervention in Hospitalized Individuals Elastography-based brief alcohol intervention - Alcoholic Liver Disease (ALD), Alcohol Use Disorder | Not applicable | Recruiting | Oslo University Hospital | 500 | 2026-09-14 | 2026-10-22 |
| A Study to Investigate the Safety and Efficacy of Efimosfermin Alfa Compared With Placebo in Adult Participants With Alcohol-related Liver Disease (ALD) Efimosfermin alfa, Placebo - Liver Diseases, Alcoholic | Phase 2 | Recruiting | GlaxoSmithKline | 274 | 2026-08-31 | 2026-09-30 |
| Financial Rewards for Reducing Alcohol Use in Patients With Liver Disease PEth Based Contingency Management, PEth Monitoring with Fixed Incentives - Alcohol Use Disorder, Alcohol-associated Liver Disease | Not applicable | Not yet recruiting | Massachusetts General Hospital | 90 | 2026-08-01 | 2026-03-12 |
| A-TANGO Phase 2 Study Placebo, TAK-242, G-CSF (Filgrastim) - Acute-On-Chronic Liver Failure, Alcoholic Hepatitis | Phase 2 | Recruiting | Yaqrit Ltd | 78 | 2026-06-29 | 2026-09-21 |
| PROlonged Corticosteroid Treatment or N-ACetylcysteine for Severe Alcoholic Hepatitis N-Acetylcysteine (NAC) Treatment, Prednisolone, Placebo of N-acetylcysteine - Alcoholic Hepatitis | Phase 3 | Recruiting | University Hospital, Lille | 477 | 2026-05-22 | 2026-06-01 |
| The Efficacy of Tocotrienol Rich Fraction for Liver Protection in Adult Patients With Alcoholic Fatty Liver Disease (AFLD) Palm Tocotrienol Rich Fraction (TRF), Refined, bleached, and deodorised (RBD) palm olein - Alcoholic Fatty Liver Disease | Phase 2 | Not yet recruiting | Universiti Kebangsaan Malaysia Medical Centre | 26 | 2026-05-02 | 2026-04-29 |
| Personalized Transcranial Magnetic Stimulation (TMS) for Metabolic Dysfunction and Alcohol-Related Liver Disease Individually Targeted rTMS, Conventional rTMS, Transcranial Magnetic Stimulation Sham - Liver Diseases, Alcoholic, Fatty Liver | Not applicable | Not yet recruiting | The Affiliated Hospital of Hangzhou Normal University | 105 | 2026-02-01 | 2026-02-10 |
| Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH) Larsucosterol, Placebo - Hepatitis | Phase 3 | Recruiting | Bausch Health Americas, Inc. | 350 | 2026-01-29 | 2026-10-15 |
| Alcohol Consumption and Plasma cfDNA Methylation in Chronic Hepatitis B Alcohol Consumption - Chronic Hepatitis B, Alcoholic Hepatitis | Completed | Beijing Municipal Administration of Hospitals | 85 | 2025-11-21 | 2026-10-08 | |
| Alcohol Misuse Treatment to Patients Newly Diagnosed With Alcohol-related Liver Disease: a Randomized Controlled Trial Offer of specialized alcohol use disorder treatment in the hepatology clinic - Liver Diseases, Alcoholic, Alcohol Use Disorder | Not applicable | Recruiting | Zealand University Hospital | 221 | 2025-11-15 | 2025-11-18 |
| LiverTREM-1: Hepatic TREM-1 Expression and Prognosis in Severe Alcoholic Hepatitis TREM-1 expression (via immunohistochemistry) between SAH patients and controls - Severe Alcoholic Hepatitis | Not yet recruiting | Central Hospital, Nancy, France | 300 | 2025-10-01 | 2025-09-16 | |
| Health Literacy and Self-efficacy Expectations in Patients With Alcohol-related Liver Cirrhosis Self-Efficacy, Health Literacy | Recruiting | Hannover Medical School | 200 | 2025-08-11 | 2025-09-11 | |
| Gepaktiv vs UDCA and Ademetionine in MAFLD With Hepatomegaly Dietary supplement "Gepaktiv", UDCA (Ursodeoxycholic acid), Ademetionine - Metabolic Dysfunction-associated Fatty Liver Disease (MAFLD), Hepatomegaly | Not applicable | Recruiting | Phenomen Pharma | 90 | 2025-06-19 | 2025-07-23 |
| Investigating HepQuant DuO Test as a Biomarker in Alcohol-related Liver Disease HepQuant DuO Test - Alcoholic Hepatitis, Alcohol-related Liver Disease | Recruiting | HepQuant, LLC | 40 | 2025-06-10 | 2026-09-16 | |
| Long-term Follow-up to Determine Outcome in Liver Disease (LOVE Study) Steatotic Liver Disease, MASLD/MASH (Metabolic Dysfunction-Associated Steatotic Liver Disease / Metabolic Dysfunction-Associated Steatohepatitis) | Not yet recruiting | Universität des Saarlandes | 30000 | 2025-04-15 | 2025-04-02 | |
| Short Course Steroids in Alcohol Associated Hepatitis Prednisolone 40 mg - Alcoholic Hepatitis | Phase 3 | Completed | Asian Institute of Gastroenterology, India | 151 | 2025-04-07 | 2026-09-01 |
| Randomized Controlled Trial of Mycophenolate Mofetil Versus Steroid Therapy in Alcoholic Hepatitis Mycophenolate Mofetil, Prednisone - Alcoholic Hepatitis | Not applicable | Not yet recruiting | Institute of Liver and Biliary Sciences, India | 60 | 2025-01-20 | 2025-01-23 |
| Nutritional Interventions in Patients With Alcohol-associated Hepatitis Nutritional supplement - Alcoholic Hepatitis | Not applicable | Unknown | Western University, Canada | 2000 | 2025-01-01 | 2024-05-29 |
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Hepatitis, Alcoholic (108) · Liver Cirrhosis, Alcoholic (44) · Fibrosis (28) · Alcoholism (24) · Liver Cirrhosis (23) · Liver Diseases (17) · Non-alcoholic Fatty Liver Disease (13) · Hepatitis (8) · Carcinoma, Hepatocellular (7) · Fatty Liver (6) · Fatty Liver, Alcoholic (6) · Infections (6) · Liver Failure (5) · Ascites (4)
Chemically-Induced Disorders (207) · Substance-Related Disorders (207) · Digestive System Diseases (206) · Alcohol-Induced Disorders (205) · Alcohol-Related Disorders (204) · Liver Diseases (190) · Hepatitis (108) · Pathological Conditions, Signs and Symptoms (86) · Pathologic Processes (85) · Fibrosis (48) · Liver Cirrhosis (40) · Mental Disorders (26) · Infections (15) · Fatty Liver (13)
Prednisolone (11) · Granulocyte Colony-Stimulating Factor (7) · Pentoxifylline (7) · Acetylcysteine (6) · Ethanol (6) · Blood Specimen Collection (5) · Fecal Microbiota Transplantation (5) · Liver Transplantation (4) · Prednisone (4) · Probiotics (4) · Standard of Care (4) · Adrenal Cortex Hormones (3) · Baclofen (3) · Methylprednisolone (3) · S-Adenosylmethionine (3)
Institute of Liver and Biliary Sciences, India (11) · Erasme University Hospital (7) · University Hospital, Lille (7) · Assistance Publique - Hôpitaux de Paris (6) · The Cleveland Clinic (6) · University of Aarhus (6) · Chuncheon Sacred Heart Hospital (5) · Indiana University (5) · Pharmicell Co., Ltd. (5) · Post Graduate Institute of Medical Education and Research, Chandigarh (5) · Asian Institute of Gastroenterology, India (3) · Copenhagen University Hospital, Hvidovre (3) · University Hospital, Montpellier (3) · University of Alabama at Birmingham (3) · University of Pittsburgh (3)
United States (66) · France (31) · India (23) · United Kingdom (18) · Denmark (17) · South Korea (14) · Belgium (10) · China (7) · Germany (6) · Spain (6) · Canada (4) · Italy (4) · Australia (3) · Mexico (3) · Zambia (3)
Michael J Vinikoor, MD (3) · Arnaud Lemmers, MD (2) · Christophe Moreno, MD, PhD (2) · Craig J McClain, MD (2) · Ki Tae Suk, PhD (2) · Moonyoung Kim (2) · Naga Chalasani, MD (2) · Philippe Mathurin, MD,PhD (2) · Robert S Brown, MD, MPH (2) · Santiago Tome, MD (2) · Soon Koo Baik, M.D.,Ph.D (2) · Srinivasan Dasarathy, MD (2) · . Prasanna Samuel Premkumar, PhD (1) · Abigail Smith (1) · Abigail Smith, PhD (1)
PMID 37011138, PMID 16026887, PMID 19553649, PMID 31811953, PMID 35084335, PMID 38215876, PMID 10782906, PMID 11113085, PMID 11172350, PMID 11605686, PMID 11943418, PMID 14647046, PMID 14653766, PMID 15122768, PMID 1531090, PMID 15349802, PMID 15618643, PMID 15763232, PMID 16009691, PMID 17204261, PMID 17518367, PMID 18068515, PMID 18270828, PMID 1828447, PMID 18721242, PMID 19058754, PMID 19177575, PMID 19340904, PMID 19445945, PMID 19560604, PMID 19821406, PMID 20334708, PMID 20561703, PMID 21085006, PMID 21334404, PMID 2142869, PMID 22044287, PMID 22070475, PMID 22388710, PMID 22633836, PMID 22821948, PMID 23029716, PMID 23101983, PMID 2358784, PMID 23737845, PMID 23782511, PMID 23855300, PMID 23870864, PMID 23939511, PMID 24026598
P50AA027054 (2), U01AA021788 (2), U01AA021840 (2), U01AA021886 (2), U01AA021891 (2), U01AA021893 (2), U24DK130164 (2), 2004 (1), 2014 (1), 2016 (1), 2025 (1), K01TW009998 (1), K23AA018399 (1), P50AA024337 (1), R01AA014562 (1)