19 completed, 4 unknown, 3 withdrawn, 2 enrolling by invitation. 19 Not applicable, 5 Phase 1, 3 Phase 2, 3 Phase 3, 1 Early Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Peppermint Oil Aromatherapy on Pain, Functional Capacity and Cost in Fibromyalgia Patients Peppermint Oil, sweet almond oil, Duloxetine - Fibromyalgia, Aromatherapy | Not applicable | Enrolling by invitation | Bilecik Seyh Edebali Universitesi | 175 | 2026-03-01 | 2026-09-17 |
| Effect of Cardamom and Peppermint Oils on Chemotherapy-Related Nausea-Vomiting and Food Intake Peppermint Oil, cardomom oil, sweet almond oil - Cancer | Not applicable | Not yet recruiting | Semanur Bilgiç | 39 | 2026-01-01 | 2026-01-06 |
| Endourage Complete Spectrum Oral Mucosal Drops (OMD) in Adults Desiring a Reduction in Ethanol Use Endourage 1200 mg OMD ™ Oral Mucosal Drops, Isolate, Placebo - Alcohol Drinking, Alcohol Use, Unspecified | Not applicable | Withdrawn | Endourage, LLC | 2025-09-01 | 2025-08-07 | |
| Effects of Peppermint Oil in Pre-metabolic Syndrome Peppermint Oil, Placebo - Pre-metabolic Syndrome | Not applicable | Completed | University of Central Lancashire | 40 | 2025-01-01 | 2026-10-16 |
| Enteric-Coated Peppermint Oil Versus Standard Antispasmodic in SLC6A4 (5-HTTLPR) Carriers With Irritable Bowel Syndrome. Peppermint Oil, A standard antispasmodic - Irritable Bowel Syndrome (IBS) | Not applicable | Completed | S.LAB (SOLOWAYS) | 224 | 2024-02-04 | 2025-04-23 |
| Effects of Peppermint Oil in Mild-moderate Hypertension. Peppermint oil, Placebo - Hypertension | Not applicable | Completed | University of Central Lancashire | 40 | 2024-01-01 | 2026-01-15 |
| Menoupausal Symptoms and Aromatherapy Lemon oil, peppermint oil, Almond oil - Aromatherapy | Not applicable | Completed | KTO Karatay University | 90 | 2022-12-27 | 2023-03-01 |
| Peppermint Oil as a Treatment for Children With Bladder and Bowel Dysfunction Peppermint Oil - Bladder and Bowel Dysfunction | Not applicable | Enrolling by invitation | Children's Hospital of Orange County | 30 | 2022-11-01 | 2026-04-08 |
| Use of Aromatherapy in Conjunction With Physical/Occupational Therapy in an Acute Care Setting Lavender Oil, Mandarin Oil, Peppermint oil - Suffering, Physical, Nausea | Phase 1 | Completed | The University of Texas Health Science Center at San Antonio | 165 | 2022-05-16 | 2026-06-16 |
| Peppermint Oil for the Treatment of Irritable Bowel Syndrome or Functional Abdominal Pain in Children: the MINT Study Small intestinal release peppermint oil, Peppermint sweets, Placebo - Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome | Phase 3 | Completed | St. Antonius Hospital | 228 | 2022-05-12 | 2025-05-30 |
| Effects of Massage With Peppermint Oil on Labor Pain massage with peppermint oil - Labor Pain | Not applicable | Completed | Ankara City Hospital Bilkent | 60 | 2021-11-13 | 2023-07-27 |
| Effects of Peppermint Oil in Cardiometabolic Outcomes Peppermint oil., Placebo - Cardiometabolic Syndrome | Not applicable | Completed | University of Central Lancashire | 36 | 2021-11-01 | 2023-03-31 |
| Peppermint Oil for the Treatment of Interstitial Cystitis / Bladder Pain Syndrome Peppermint oil, Coconut Oil - Interstitial Cystitis | Phase 1 / Phase 2 | Recruiting | University of Louisville | 100 | 2021-09-15 | 2022-08-22 |
| Androgenetic Alopecia Treatment Using Varin and Cannabidiol Rich Topical Hemp Oil: A Case Series Hemp Oil - Androgenetic Alopecia | Early Phase 1 | Unknown | Gregory L Smith, MD, MPH | 40 | 2021-04-05 | 2021-04-15 |
| The Effect of Ginger and Peppermint on Postoperative Nausea and Vomiting in Patients After Thyroid Surgery Ginger, Peppermint - Postoperative Nausea and Vomiting | Not applicable | Unknown | Sona PASHAEI | 81 | 2021-03-01 | 2021-05-19 |
| Peppermint Oil Pharmacokinetics/Dynamics Peppermint oil - Abdominal Pain | Phase 1 | Withdrawn | Baylor College of Medicine | 2020-07-09 | 2023-12-11 | |
| Food Supplements Based on Nettle and Peppermint to Control Signs and Symptoms Induced by Cancer Therapies Stinging Nettle, Peppermint - Breast Cancer, Gynecologic Cancer | Not applicable | Unknown | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 60 | 2019-06-20 | 2020-07-17 |
| Does Aromatherapy Decrease Postoperative Nausea and Vomiting? Peppermint oil - Nausea, Postoperative | Not applicable | Completed | The University of Texas Medical Branch, Galveston | 50 | 2018-06-15 | 2019-01-09 |
| Reducing Up-set Stomach and Vomiting After Surgery Using Essential Oils Peppermint oil, Ginger oil - Nausea | Not applicable | Completed | University of Rochester | 143 | 2018-03-12 | 2018-09-04 |
| Peppermint Oil Pharmacokinetics/Dynamics and Novel Biological Signatures in Children With Functional Abdominal Pain Peppermint oil - Abdominal Pain | Phase 1 | Completed | Robert Shulman, M.D. | 30 | 2017-10-15 | 2022-04-06 |
Showing 20 of 31. Sign in to see all of them.
Irritable Bowel Syndrome (5) · Nausea (5) · Abdominal Pain (3) · Pain (2) · Postoperative Nausea and Vomiting (2) · Vomiting (2) · Alcohol Abstinence (1) · Alcohol Drinking (1) · Alcohol-Related Disorders (1) · Alopecia (1) · Anemia (1) · Breast Neoplasms (1) · Colonic Diseases (1) · Colonic Neoplasms (1) · Colonic Polyps (1)
University of Central Lancashire (3) · Ankara City Hospital Bilkent (1) · Baylor College of Medicine (1) · Beth Israel Deaconess Medical Center (1) · Bilecik Seyh Edebali Universitesi (1) · Centre for Addiction and Mental Health (1) · Charite University, Berlin, Germany (1) · Children's Hospital of Orange County (1) · Endourage, LLC (1) · Gregory L Smith, MD, MPH (1) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (1) · KTO Karatay University (1) · Maastricht University Medical Center (1) · Mayo Clinic (1) · Medical College of Wisconsin (1)
United States (14) · Turkey (Türkiye) (6) · United Kingdom (3) · Netherlands (2) · Canada (1) · Germany (1) · Italy (1) · Russia (1) · Taiwan (1)
A Masclee, Prof, PhD, MD (1) · Adrian Miranda, MD (1) · Arine Vlieger, MD, PhD (1) · Bernard Le Foll (1) · Bianca Gonzales, OTR, CNT, EdD, MOT (1) · Claudio Zamagni, MD (1) · David O Kennedy, PhD (1) · Gregory L Smith, MD (1) · Heidi A. Stephany, MD (1) · Kevin C Ruff (1) · Maxine Fearrington, MS (1) · Michelle S Karsten, RN, BSN (1) · Ming-Chih Hou, MD (1)
PMID 12648025, PMID 16251991, PMID 16699809, PMID 18422832, PMID 18973181, PMID 26373473, PMID 28545508, PMID 29307505, PMID 30284674, PMID 33605656, PMID 34528282, PMID 35048535, PMID 35729250, PMID 37743153, PMID 40333716, PMID 41610933, PMID 42024666
2014 (1), R01AT008573 (1), R21CA158530 (1)