7 completed, 2 not yet recruiting, 1 terminated, 1 unknown. 12 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 12 | Completed 7, Not yet recruiting 2, Terminated 1, Unknown 1, Withdrawn 1 |
Follow Aged: new trials by email Literature Review of Aged trials Research Report on Aged
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Remimazolam vs Midazolam to Reduce Delirium in Adults ≥65 Undergoing CPB Valve Surgery Midazolam, Remimazolam - Delirium, Critical Illness | Phase 4 | Not yet recruiting | Yonsei University | 300 | 2025-12-01 | 2025-12-04 |
| Preoperative Use of Peripheral Nerve Blocks in Elderly Patients With Hip Fractures PENG and LFCN peripheral nerve blocks with spinal anesthesia, FN and LFCN peripheral nerve blocks with spinal anesthesia, FIC peripheral nerve block with spinal anesthesia - Fractures, Hip, Femoral Neck Fractures | Phase 4 | Not yet recruiting | University Hospital of Split | 256 | 2025-08-30 | 2025-08-19 |
| Impact of Maxigesic on Delirium After Minimally Invasive Lung Surgery in Elderly Patients Acetaminophen and Ibuprofen, Normal saline - Delirium, Aged | Phase 4 | Terminated | Korea University Guro Hospital | 25 | 2023-06-15 | 2025-09-05 |
| Bivalirudin in Elderly Patients With Acute ST-segment Elevation Myocardial Infarction Bivalirudin, Heparin - STEMI, Percutaneous Coronary Intervention | Phase 4 | Unknown | The First Affiliated Hospital of Dalian Medical University | 240 | 2019-01-16 | 2019-03-20 |
| Impacts of Low-Dose Dexmedetomidine on Sleep Quality in Mechanically Ventilated ICU Patients Dexmedetomidine, Placebo (normal saline) - Aged, Postoperative Period | Phase 4 | Completed | Peking University First Hospital | 80 | 2017-11-17 | 2019-12-11 |
| The Effect of Age on the Median Effective Dose (ED50) of Intranasal Dexmedetomidine for Rescue Sedation Following Failed Sedation With Oral Chloral Hydrate During Magnetic Resonance Imaging intranasal dexmedetomidine - Aged, Drug | Phase 4 | Completed | Guangzhou Women and Children's Medical Center | 120 | 2014-10-01 | 2016-03-29 |
| Dexmedetomidine and Long-term Outcome in Elderly Patients After Surgery dexmedetomidine, placebo - Aged, Surgical Procedures, Operative | Phase 4 | Completed | Peking University First Hospital | 700 | 2011-05-01 | 2017-06-16 |
| Fall Prevention by Alfacalcidol and Training Alfacalcidol, Balance, gait and strength training, Patient education - Accidental Falls, Chronic Renal Insufficiency | Phase 4 | Withdrawn | Ruhr University of Bochum | 484 | 2007-06-01 | 2011-07-21 |
| Duloxetine Treatment of Major Depression and Chronic Low Back Pain For Older Adults Duloxetine - Major Depressive Disorder, Back Pain | Phase 4 | Completed | University of Pittsburgh | 30 | 2007-05-01 | 2017-02-01 |
| Study of Evaluation Indexes for Antibody Production in Sera After Immunization pneumococcal polysaccharide vaccine - Aged | Phase 4 | Completed | Ewha Womans University | 70 | 2005-04-01 | 2009-08-25 |
| Valsartan in Elderly Isolated Systolic Hypertension Study target blood pressure - Aged, Systolic Hypertension | Phase 4 | Completed | VALISH study | 3079 | 2003-10-01 | 2015-06-04 |
| Study Evaluating Two Different Sirolimus-based Immunosuppressive Regimens in Elderly Kidney Transplant Recipients Sirolimus - Kidney Failure, Graft Rejection | Phase 4 | Completed | Wyeth is now a wholly owned subsidiary of Pfizer | 66 | 2002-10-01 | 2012-01-31 |
Delirium (3) · Back Pain (1) · Cardiovascular Diseases (1) · Critical Illness (1) · Depressive Disorder, Major (1) · Emergence Delirium (1) · Femoral Neck Fractures (1) · Hip Fractures (1) · Isolated Systolic Hypertension (1) · Lung Neoplasms (1) · Renal Insufficiency (1) · Renal Insufficiency, Chronic (1) · ST Elevation Myocardial Infarction (1) · Sleep Initiation and Maintenance Disorders (1) · Sleep Wake Disorders (1)
Pathological Conditions, Signs and Symptoms (7) · Mental Disorders (5) · Neurologic Manifestations (5) · Signs and Symptoms (5) · Nervous System Diseases (4) · Pathologic Processes (4) · Confusion (3) · Neurobehavioral Manifestations (3) · Neurocognitive Disorders (3) · Disease Attributes (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Kidney Diseases (2) · Male Urogenital Diseases (2) · Urogenital Diseases (2)
Saline Solution (3) · Dexmedetomidine (2) · 23-valent pneumococcal capsular polysaccharide vaccine (1) · Acetaminophen (1) · Anesthesia, Spinal (1) · Control Groups (1) · Duloxetine Hydrochloride (1) · Fentanyl (1) · Gait (1) · Heparin (1) · Ibuprofen (1) · Midazolam (1) · Patient Education as Topic (1) · Pneumococcal Vaccines (1) · Resistance Training (1)
Peking University First Hospital (2) · Ewha Womans University (1) · Guangzhou Women and Children's Medical Center (1) · Korea University Guro Hospital (1) · Ruhr University of Bochum (1) · The First Affiliated Hospital of Dalian Medical University (1) · University Hospital of Split (1) · University of Pittsburgh (1) · VALISH study (1) · Wyeth is now a wholly owned subsidiary of Pfizer (1) · Yonsei University (1)
China (4) · South Korea (3) · Croatia (1) · Germany (1) · Japan (1) · United States (1)
Ana Bego, MD (1) · Ana Maria Mitar, MD (1) · Ana Saric Jadrijev, MD (1) · Boris Luksic, MD, PhD (1) · Dong-Xin Wang, MD, PhD (1) · Dong-Xin Wang, MD,PhD (1) · Heezoo Kim, MD, PhD (1) · Jordan F Karp, MD (1) · Josipa Modric, MD (1) · Kyung-Hyo Kim, Doctor (1) · Marija Kljucevic, MD (1) · Meri Mirceta, MD (1) · Nikola Delic, MD, PhD (1) · Nikola Kljucevic, MD, PhD (1)
PMID 19750557, PMID 20219110, PMID 20530299, PMID 27627818, PMID 28049699, PMID 36117973