4 recruiting, 3 not yet recruiting, 1 completed. 8 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 8 | Recruiting 4, Not yet recruiting 3, Completed 1 |
Follow Acute Heart Failure (AHF): new trials by email Literature Review of Acute Heart Failure (AHF) trials Research Report on Acute Heart Failure (AHF)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intravenous Infusion of Low Dose Ketamine Versus Dexmedetomedine for Delirium Treatment in Acute Heart Failure Low dose ketamine infusion, Dexmedetomidine infusion - Delirium in Intensive Care Unit, Acute Heart Failure (AHF) | Phase 4 | Not yet recruiting | Alexandria University | 150 | 2026-09-01 | 2026-08-24 |
| TACTIC-HF: Sequential Diuretic Strategies in Ambulatory Worsening Heart Failure Intravenous furosemide bolus injections, ACETAZOLAMIDE oral capsule, Hydrochlorothiazide (HCT) - Acute Heart Failure (AHF) | Phase 4 | Not yet recruiting | Lucrecia Maria Burgos | 60 | 2026-06-15 | 2026-05-18 |
| Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure Ketone Monoester (KE) - Acute Heart Failure (AHF), Cardiogenic Shock | Phase 4 | Recruiting | Institute for Clinical and Experimental Medicine | 12 | 2026-04-04 | 2026-04-14 |
| Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure Furosemide intravenous solution - Heart Failure, Heart Failure - NYHA II - IV | Phase 4 | Recruiting | Lakeland Regional Health Systems, Inc. | 600 | 2026-04-01 | 2026-04-09 |
| Digoxin After Acute Heart Failure (DIG-DICA) Usual Care, Digoxin - Acute Heart Failure (AHF) | Phase 4 | Recruiting | Hospital General de Agudos "Dr. Cosme Argerich" | 120 | 2025-12-16 | 2026-06-02 |
| Pre-discharge Influenza Vaccination in Patients Hospitalized for Acute Cardiac Conditions Influenza vaccination - Myocardial Infarction, Decompensated Chronic Heart Failure | Phase 4 | Recruiting | Wroclaw Medical University | 400 | 2025-11-12 | 2026-06-01 |
| Efficacy and Safety of Early Initiation of Vericiguat in Heart Failure After Acute Myocardial Infarction Vericiguat - Heart Failure, Acute Myocardial Infarction (AMI) | Phase 4 | Not yet recruiting | Dongying Zhang | 200 | 2025-04-01 | 2025-02-06 |
| Evaluating the Effects of Nitroglycerin on Heart Function and Urinary Output in Patients With Acute Heart Failure Nitroglycerin (NTG) - Acute Heart Failure (AHF) | Phase 4 | Completed | Copenhagen University Hospital, Hvidovre | 21 | 2025-02-01 | 2026-03-18 |
Heart Failure (4) · Aneurysm (1) · Arrhythmias, Cardiac (1) · Delirium (1) · Heart Failure, Systolic (1) · Influenza, Human (1) · Ketosis (1) · Myocardial Infarction (1) · Shock, Cardiogenic (1)
Cardiovascular Diseases (7) · Heart Diseases (6) · Pathological Conditions, Signs and Symptoms (3) · Vascular Diseases (3) · Infarction (2) · Ischemia (2) · Myocardial Ischemia (2) · Necrosis (2) · Pathologic Processes (2) · Acid-Base Imbalance (1) · Acidosis (1) · Confusion (1) · Heart Failure (1) · Infections (1) · Mental Disorders (1)
Acetazolamide (1) · Digoxin (1) · Furosemide (1) · Hydrochlorothiazide (1) · Influenza Vaccines (1) · Nitroglycerin (1) · vericiguat (1)
Alexandria University (1) · Copenhagen University Hospital, Hvidovre (1) · Dongying Zhang (1) · Hospital General de Agudos "Dr. Cosme Argerich" (1) · Institute for Clinical and Experimental Medicine (1) · Lakeland Regional Health Systems, Inc. (1) · Lucrecia Maria Burgos (1) · Wroclaw Medical University (1)
Argentina (1) · China (1) · Czechia (1) · Denmark (1) · Egypt (1) · Poland (1) · United States (1)
Anas Bizanti, MD (1) · Andrew Lurie, DO (1) · Dongying Zhang, Professor (1) · Guillermo Ernesto Liniado, MD (1) · Jan Biegus, Professor (1)
PMID 14744970, PMID 22357361, PMID 24621874, PMID 29496021, PMID 31535829, PMID 32222134, PMID 34449189